KEGG   Kosakonia sp. SMBL-WEM22: HF650_06820
Entry
HF650_06820       CDS       T08549                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
kob  Kosakonia sp. SMBL-WEM22
Pathway
kob00290  Valine, leucine and isoleucine biosynthesis
kob00620  Pyruvate metabolism
kob01100  Metabolic pathways
kob01110  Biosynthesis of secondary metabolites
kob01210  2-Oxocarboxylic acid metabolism
kob01230  Biosynthesis of amino acids
Module
kob_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:kob00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HF650_06820 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HF650_06820 (leuA)
Enzymes [BR:kob01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HF650_06820 (leuA)
SSDB
Motif
Pfam: HMGL-like IPMS_D2 LeuA_dimer
Other DBs
NCBI-ProteinID: QNQ19491
UniProt: A0A7H0MB30
LinkDB
Position
complement(1426131..1427801)
AA seq 556 aa
MLTTPAEKYHPHAPLPLRDRRWPDNTLTHAPRWLSTDLRDGNQALAEPMDAARKLKFWDL
LLECGFKEIEVAFPSASQTDFSFVRQLIEEQRIPEDVTIQVLTQARDDLIRRTFESLQGA
RRATVHLYNATAPVFREQVFRQSKEEIVTLAVNAARQIRTQCEAAPETQWVFQYSPETFC
FTEAEFALAICEAVADVWQPDETRPMIINLPATVEVSMPNVYADQIEHFCRHFSRREQVC
ISVHTHNDRGTGIASAELALLAGAERVEGCLFGNGERTGNADLVTLALNLYTQGIAPGLE
FSQMKKVVEVVEECNQLPVAPRHPYAGELVFTAFSGSHQDAIKKGFAARQNSTADVWQVP
YLPLDPADIGCSYEAVIRVNSQSGKSGAAWLLEQNHGLALPRKLQQAFSGHVQQAADSAG
KEMSQMAIWNLFRQTYGLVDQPPLALIEYVCTNQPGQRTILHAEIRWHNETLKLDGTGNG
FLSAALTALCRSLRVEINIESYHEHTLGKHSDSRSVAYVCCANARGERAWGVSIDSDITR
ASLQAVLNAAQPFITG
NT seq 1671 nt   +upstreamnt  +downstreamnt
atgttaacgacccctgctgaaaaatatcatccccatgccccactgccgctgcgcgatcgc
cgctggccggataacacgctgacccacgcgccgcgctggctgtcgacggatttacgcgac
ggcaaccaggctcttgccgagccgatggatgcggcacgcaaactaaaattctgggatctc
ttgctggagtgcggctttaaggagattgaggtcgccttcccctctgcctcgcaaacggac
tttagctttgtgcgccagttgattgaggagcaacgcattcctgaagatgtcaccattcag
gtgttaacccaggcgcgtgacgatctgattcgccgcacctttgaatccttgcagggcgcg
cgccgcgcgaccgtacatctctacaacgctaccgcgccggtgttccgcgagcaggttttc
cgccagagcaaggaggagatcgtcacgctggcggtcaacgcggcgcggcaaatccgcacg
cagtgcgaagccgcaccagagacgcagtgggtgttccagtattcgccggaaaccttctgc
tttaccgaagcggagttcgcgctggcgatttgcgaagcggtggccgatgtctggcaaccg
gacgaaacccggccaatgatcatcaacctgccggccaccgttgaggtgagcatgcccaat
gtctatgccgaccagattgagcacttctgccgtcacttctcgcgccgcgagcaggtgtgc
atcagcgtacatacccataacgatcgcggcaccggcattgccagcgccgaattggcgctg
ctggcaggcgcagagcgggttgaaggctgcctgtttggcaacggcgagcgcaccggcaat
gccgatctggtgacgctggcgctcaatctctacacccagggcatcgcgccgggccttgag
tttagccagatgaaaaaggtggtagaggtagtcgaagagtgtaaccagttgccggttgcg
ccgcgccacccctacgccggtgaactggtgtttaccgccttttccggctcgcaccaggac
gcgattaagaaaggatttgccgcgcggcaaaacagcacggcggacgtctggcaggtgccc
tatctgccgctcgacccggcggatatcggctgtagctacgaagcggttattcgcgtcaac
agccagtcgggcaagagcggcgcggcctggctgctggagcagaaccacggcctggcgctg
ccgcgtaagcttcagcaggcgttcagcgggcatgtgcagcaggcggcggacagcgcgggc
aaagagatgtcgcaaatggcgatctggaatctgtttcgccagacctacggcctggtggat
cagccgccgctggcgttaattgagtatgtctgcaccaaccagccggggcagcgcaccatc
ctgcacgcggagatccgctggcataacgagacgctgaagctggatgggacgggcaacggt
tttctctcggcggcgttaaccgcgctctgccgcagcctgcgcgttgagatcaatattgag
agctaccacgaacacacgctcggcaaacacagcgacagccgctcggtggcctatgtctgc
tgcgccaacgcgcgcggcgagcgcgcatggggcgtcagtatcgacagcgatatcacccgc
gcctcactgcaggcggtgcttaacgccgcacagccctttatcactgggtaa

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