Kosakonia sp. SMBL-WEM22: HF650_16325
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Entry
HF650_16325 CDS
T08549
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
kob
Kosakonia sp. SMBL-WEM22
Pathway
kob00790
Folate biosynthesis
kob01100
Metabolic pathways
kob01240
Biosynthesis of cofactors
Module
kob_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
kob00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
HF650_16325 (folC)
Enzymes [BR:
kob01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
HF650_16325 (folC)
6.3.2.17 tetrahydrofolate synthase
HF650_16325 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QNQ21194
UniProt:
A0A7H0MFY3
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Position
complement(3401065..3402333)
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AA seq
422 aa
AA seq
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MDTLSTPQATSPLAAWLSYLEQLHSKPIDLGLDRVSQVAARLDVLRPAPFVFTVAGTNGK
GTTCRTLESILLAAGYRVGVYSSPHLVRYTERVRVQGGELAESAHTASFAEIEAVRGDIS
LSYFEFGTLSALWLFKQAQLDVVILEVGLGGRLDATNMVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRIGKPAVVGEPDMPHTIADVAQEKGAQLLQRDVAWHYEVGAQSWRFRD
EQGELSDLPLPQVPQPNAATALAALRASKLNVSEQAIRDGIARAILPGRFQVVSQSPRLI
LDVAHNPHAARYLAGRLVALPNRGRVLAVVGMLHDKDISGTLACLEPVVDSWYCAPLEGP
RGATAEQLLAHLTSGQAFPDVTQAWQAAMAEADACDTVLVCGSFHTVAHVMEAMEAGRTG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggatactctctctactccgcaagccacgtcgcccctggccgcatggctctcatatctg
gaacagctgcacagtaaacctatcgatttagggctcgatcgcgtaagccaggtggcggcg
cggcttgatgtgctgcgtcccgcaccctttgtcttcaccgtcgccggaaccaacggcaaa
ggcaccacctgccgcacgctggagtcgattctgctggcggccggttatcgcgtcggggtt
tacagctcaccgcatctggtgcgctacaccgaacgtgtacgcgtgcagggcggggagctg
gcagaaagcgcacacactgcctccttcgcggagatcgaagccgtgcgcggcgatatctcc
ctaagctattttgaatttggcaccctgtcggcgctgtggctgtttaagcaggcgcagctg
gatgtggtgatcctcgaagtgggtcttggcggtcgccttgacgcgaccaatatggttgac
gccgatgtcgcggtggtcaccagcattgcgctcgatcataccgactggctcggcccggat
cgcgaaagcatcggccgtgaaaaagcgggcatcttccgcatcggtaaacctgcggtggtc
ggcgagccggatatgccgcacaccatcgctgacgtcgcgcaagagaagggcgcgcagctg
ttgcagcgtgatgtggcgtggcactacgaggttggcgcacagagctggcgtttccgtgac
gagcagggcgagctgagcgatttgccgctgccgcaggtgccgcagcctaacgctgctacc
gcgctggccgcgctgcgcgccagtaaactaaatgtgagcgagcaggcaattcgtgacggc
attgcgcgggcgattttaccgggtcgttttcaagtggtgagccaatcaccgcggcttatt
ctcgatgtcgcacataaccctcatgctgcacgctatcttgccggtcggctggtagcgttg
ccgaatcgtggtcgcgtactggcggtggtcggcatgctgcatgataaagacatcagtgga
acgcttgcctgtctggagccggtggtcgatagctggtattgtgcccctctggaggggccg
cgtggcgcgacggcggaacagctgctggcgcatctgacgtcgggacaagcattcccggac
gtgacccaggcctggcaggcggcaatggcggaggccgacgcctgcgataccgtgctggtg
tgtggctcgttccacaccgtggcgcatgtcatggaagcgatggaagcggggagaaccggt
ggcaagtaa
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