Klebsiella oxytoca KONIH1: KONIH1_04640
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Entry
KONIH1_04640 CDS
T03269
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kok
Klebsiella oxytoca KONIH1
Pathway
kok00300
Lysine biosynthesis
kok00550
Peptidoglycan biosynthesis
kok01100
Metabolic pathways
kok01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kok00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KONIH1_04640 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KONIH1_04640 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KONIH1_04640 (murF)
Enzymes [BR:
kok01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KONIH1_04640 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
AID88371
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Position
978810..980168
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AA seq
452 aa
AA seq
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MIRLTLSQLAGITHGELHGRDVAIDDVTSDTRKITAGCLFVALKGERFDAHDFAKQAKAA
GAGALLVSRQLACDLPQVVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPLNGIAIMNADNNDWLNWQSVIGERKTWRFS
PNAAHSDFTATNVHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMAVGATH
EAIKAGLKDLKAVPGRLFPIQLTDSQLLLDDSYNANVGSLTAAVQVLSEMPGYRVLVVGD
MAELGAESQACHRQVGEAAKAAGLDRVLSVGTLSAEISGASGVGEHFSEKAALVTRLREL
TAEHKIMTILVKGSRSAAMEVVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgcttgactctcagccagctcgccggcatcacgcatggcgagctacacggccgc
gatgtggcgattgatgacgtcacctccgatacccgtaaaatcacggcgggctgcctgttc
gtggcgctaaaaggcgagcgctttgatgcgcatgactttgccaaacaggcgaaagctgcc
ggcgcgggcgcactgttggtcagccgtcagctggcctgcgatctaccgcaggtggtggtg
aaggatacgcgtctggcgtttggcgaactggccgcgtgggtgcgtcagcaggtgccggcg
cgcgtggtcgcgctgaccggatcttccggaaaaacctcggttaaagagatgaccgcggcg
attctgagccagtgcggcaatacgctgtataccgcaggtaacctgaacaacgatatcggc
gtgccgatgacgctgctgcgtctcaccaaagaacatgactacgcggtcatcgagttaggc
gctaatcaccagggggaaattgcctggaccgttagcctgacccgtcccgaagccgcgtta
gtgaataacctggccgccgcgcacctggaaggctttggctctctggaaggcgtggcgaaa
gccaagggcgaaatctacaccggtctgccgctcaacggcatcgcgattatgaacgccgac
aataatgactggctgaactggcaaagcgtgattggcgagcgtaaaacctggcgtttttcg
ccgaacgccgcccacagcgatttcacggcaaccaacgttcatgtgacgtcgcacgggact
gaatttactctgcagaccccaacgggcagcgttgatgtactgctaccgctgccggggcgc
cataacatcgccaacgcgctggctgccgcggcgctgtcaatggcggtgggggcgacgcat
gaggcgatcaaagcgggtctgaaagatctgaaagcggtaccggggcggttattcccgatt
cagctgaccgacagccagctgctgctggatgattcctataacgccaacgtcggctcgctg
accgctgcggtacaggtgctgtctgagatgccggggtaccgggtactggtcgttggcgat
atggccgaactcggcgcggaaagccaggcgtgccatcgtcaggtgggcgaagcggcaaaa
gcggccgggctcgatcgcgtactgagcgtcggtacgttgagcgcagagatcagcggcgcc
agcggcgttggcgaacattttagcgagaaggccgcgctggtgacccgcctgcgcgagctc
accgcagaacataaaattatgaccattttagtgaagggttcacgtagtgccgccatggaa
gtggtagtacgcgcattacaggagaacggaacatgttag
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