Kosmotoga olearia: Kole_0512
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Entry
Kole_0512 CDS
T00914
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kol
Kosmotoga olearia
Pathway
kol00300
Lysine biosynthesis
kol00550
Peptidoglycan biosynthesis
kol01100
Metabolic pathways
kol01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kol00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Kole_0512
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Kole_0512
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Kole_0512
Enzymes [BR:
kol01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Kole_0512
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF4651
Motif
Other DBs
NCBI-ProteinID:
ACR79234
UniProt:
C5CEI8
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All DBs
Position
complement(558465..559871)
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AA seq
468 aa
AA seq
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MEPISLSKIIEATGGTLLSGTPDVEIFGISTDTRTIHKGDLFVALEGERFDGHYFIDEAF
KKGAIGAIVSREVESKNIIIKVRDTLKTLGDIAKIYREEFDIPVIAVTGSNGKTTTKEML
GYILTREFKTVKAKGSYNNFVGVPLTLLEMDRHTQLAVLEMETNLLGGIKRLCEIAKPSV
GVVTNIGDTHLQFLKTREGVYQEKSELVESLPEDGVAVLNADDPYVLKMKEISRTKRIVT
FGVENKSEFSASNIRVGDTFLEFTLNNNYRVKLNTISYCNVYNGLAAIAVSHVVFGLSLE
KVIDILKDFKFPSLRMELIEIPLIDRATSNEESVRIINDCYNANPQSMQEALVAVGKMNS
YTNKIAILGEMLELGEKAPEFHYQIGKICADCGFDMLITVGDLAQYMAHGAEDEGMPREN
IFVSVNNVEASDRLLRILRPGDIVLIKGSRGMKMEEIVERLRKRLGVF
NT seq
1407 nt
NT seq
+upstream
nt +downstream
nt
atggaaccgatatctttgtctaaaattattgaagctacaggtgggactttactctcggga
actcctgatgttgagatttttggcatttccaccgacactcgaacaatacacaaaggggat
ttatttgttgcgctggagggggaaagatttgatgggcattattttatagacgaagccttc
aaaaaaggagcgataggcgcaattgtgtcaagagaggttgaaagcaaaaatataattata
aaggtgagagatacacttaaaactcttggagacatagctaagatttatagagaagagttc
gacatccctgttatagcggttactggttctaatggcaaaacaaccacaaaagaaatgcta
gggtatatcttaaccagggagttcaaaactgtaaaggcaaagggaagctacaataacttt
gtgggagtaccattgaccttgttggaaatggacaggcatacgcagctggctgttctagaa
atggaaacaaatttattgggaggtataaaaaggctttgtgagatagctaaaccttcagtt
ggtgtcgttactaatattggtgatactcacctgcagtttttgaaaacaagggaaggggta
tatcaggagaaatcagaacttgtggaatctttgcctgaggatggggtagcggttttgaat
gccgatgatccatacgtattaaaaatgaaggagatatctagaacaaagcggatagttact
tttggagtagaaaataaatccgaattttcagcttctaatataagagttggggatacgttt
ctcgaatttaccctaaacaataattacagagttaaactaaatactatttcctattgtaat
gtttacaatggattagcagcaatcgctgtttcccatgtggtttttggtttgagtttagag
aaagtgatagatattctgaaagactttaaatttccctctctgcgaatggaattaatcgaa
attcctcttatagatagagcgacttcgaatgaagaaagtgtaaggattattaatgattgt
tataacgctaatcctcaatcaatgcaagaagctctggttgctgttggaaagatgaattct
tatactaataagatagcaattctgggtgaaatgctggaattgggggaaaaagctccagaa
ttccattatcagataggtaagatatgtgcggattgtggatttgacatgttgataaccgta
ggagatcttgcgcaatatatggctcatggagctgaagatgaaggtatgcccagggaaaat
atatttgtttctgtcaataatgtggaagcgtcagatcgtcttttgagaatcctgagaccg
ggtgatattgttttgatcaaaggctcgcgtggaatgaagatggaagaaatagtggagaga
ttgagaaaaaggcttggagtcttctag
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