Candidatus Kinetoplastidibacterium stringomonadis: CONE_0211
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Entry
CONE_0211 CDS
T02471
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kon
Candidatus Kinetoplastidibacterium stringomonadis
Pathway
kon00290
Valine, leucine and isoleucine biosynthesis
kon00620
Pyruvate metabolism
kon01100
Metabolic pathways
kon01110
Biosynthesis of secondary metabolites
kon01210
2-Oxocarboxylic acid metabolism
kon01230
Biosynthesis of amino acids
Module
kon_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kon00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CONE_0211
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CONE_0211
Enzymes [BR:
kon01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CONE_0211
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AGF48041
UniProt:
M1LVC2
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All DBs
Position
complement(12292..13974)
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AA seq
560 aa
AA seq
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MITKPATKYVPFRPFKEDYSDRTWPSKSITKAPIWLSTDLRDGNQALIEPMNIERKISFF
EQLLKIGFKEIEVGFPSASKTEFDFTRKLIEDDYIPDDVTISVLTQSREDLIRKTIEAVY
GAKRAIVHLYNACAPSFRKIVFNMNRDEIKQIAVNGTNLIKDLFSQYSDKTLWQYEYSIE
VFSSTELEFALDVANTVIDIFQPTVNNKLILNLPATVESSTPNIYADQIEWMKKNINNRD
NVIISVHPHNDRGTAVASAELAIMAGADRVEGCLFGHGERTGNVDLITLALNLYTQGIHP
ELDFSDIDEVRRCVEHCTQMITPPRHPYAGDLVFTAFSGSHQDAIKKGMALQKTDAIWEV
PYLPIDPADLGRNYDAVIRVNSQSGKGGVAYLLEREYGLVLPRKLQIEFSRAVQRFTDKT
GREVTAEAVYNIFKSEYLDQSSPWKLIRHRIDGDPQAAEAKHFAVEAEIECSGEKRILRG
EGNGAISAFISALGLPARIMNYHEHSLGSNTNTRAACYVELRIDHNNSIFGVGIDRDIVT
ASFRAVLSAINRHLKSEKQS
NT seq
1683 nt
NT seq
+upstream
nt +downstream
nt
atgattaccaaaccagctactaaatatgtgccatttcgcccttttaaagaagattactct
gatagaacttggcctagtaaatctataacaaaagctcctatttggctaagtactgatctg
agagatggcaatcaagcacttatcgagccaatgaatatcgaacgcaagataagtttcttt
gagcaattgctgaaaattggatttaaagaaatagaagtcggatttccttctgcatcaaaa
accgagtttgattttacaagaaagctaatagaagatgactatataccagacgatgtaaca
atttcagtattaactcaatcaagggaagacttaataagaaagactatagaagctgtttat
ggagcaaaacgtgcaatagttcatttatacaatgcatgtgcaccttcgtttagaaaaata
gtatttaatatgaatcgagatgaaattaaacaaattgccgtaaacggtactaatcttatt
aaagatctattttcacaatattcagacaaaacactttggcagtatgagtactcaatagaa
gtttttagctcaacagaattagaatttgcattagatgttgctaatactgtgatagatatt
tttcaacctactgtgaataataaactaatattaaatctacctgctacagtagaatcatcc
actccaaatatatatgcagatcaaatagaatggatgaaaaaaaatataaataatagagat
aatgttataataagtgtacatcctcataatgatcgtggtaccgcagtagcatcagctgag
ctagctattatggcaggagctgatagagtagaaggttgtttatttggacatggagagagg
actggtaatgtcgatttaataacattagctttaaacttatatactcaaggcatccatcca
gagttagatttctctgatattgatgaggtaagaaggtgtgtcgaacattgtacgcaaatg
atcacaccaccaaggcatccatatgctggggatcttgtatttacagcgttctcaggatca
catcaggatgctataaagaaaggaatggctttacaaaaaacagatgcaatatgggaagtt
ccttatcttccaatagatccagctgatttgggaagaaattatgatgctgtaatacgtgtt
aatagtcaatcaggtaaaggtggagtagcatatcttctggaaagagaatatggtttagta
ctacctagaaaattacagatagaattcagcagggctgttcaaagatttacagataaaact
ggaagagaagttacagctgaagcggtttacaatatattcaaatcagaatacttagatcaa
agctcaccatggaaactaattcgccatcgtatagatggtgatccacaagctgcagaagct
aagcattttgctgttgaagcagagatagaatgtagcggagaaaaacgcatattgcgtgga
gaaggtaatggagcaatttctgcttttatatcagcactgggattgccagcgaggataatg
aactatcatgagcattctttaggatcaaatactaatacacgtgctgcttgttacgtagaa
ttgcgcattgatcataataattctatatttggagtaggcattgacagggatattgttact
gcatcttttagagcagttcttagcgcaataaatagacatctaaaatcagaaaaacaatct
taa
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