Kosakonia sp. CCTCC M2018092: EH164_07000
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Entry
EH164_07000 CDS
T05734
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
kot
Kosakonia sp. CCTCC M2018092
Pathway
kot00790
Folate biosynthesis
kot01100
Metabolic pathways
kot01240
Biosynthesis of cofactors
Module
kot_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
kot00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
EH164_07000
Enzymes [BR:
kot01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
EH164_07000
6.3.2.17 tetrahydrofolate synthase
EH164_07000
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
AZI86818
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Position
1480345..1481613
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AA seq
422 aa
AA seq
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MDTLSTPQATSPLAAWLSYLEQLHSKPIDLGLDRVSQVATRLDVLRPAPFVFTVAGTNGK
GTTCRTLESILLAAGYRVGVYSSPHLVRYTERVRVQGGELAESAHTASFAEIEAVRGDIS
LSYFEFGTLSALWLFKQAQLDVVILEVGLGGRLDATNMVDADVAVVTSIALDHTDWLGPD
RESIGREKAGIFRTGKPAVVGEPDMPHTIAEVAQEKGAQLLQRDVAWHYEAGAQSWRFRD
AQGELNDLPLPQVPQPNAATALAALRASNLVVSEQAIRDGIERAILPGRFQIVSESPRLI
LDVAHNPHAASYLAGRLAALPKSGRVLAVVGMLHDKDISGTLACLEPVVDSWYCAPLEGP
RGATAEQLLVHLTSGQAFPDVAQAWQAAMAEADACDTVLVCGSFHTVAHVMEAMEAGRTG
GK
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atggacactctctctactccgcaagccacgtcgcccctggccgcatggctctcttatctg
gaacagctgcacagtaaacctatcgatttagggctcgatcgcgtaagccaggtggcgacg
cggcttgatgtgctgcgtcccgcaccttttgtcttcaccgtcgccggaaccaacggcaaa
ggcaccacctgccgcacgctggagtcgatcctgctggcggccggttatcgcgtgggcgtt
tacagctcgccgcatctggtgcgctacaccgaacgcgtacgtgtgcagggcggggagctg
gcagaaagcgcgcacaccgcttccttcgcggagatcgaagccgtgcgcggcgatatctct
ttaagctattttgaatttggcaccctgtcggcgctgtggctctttaagcaggcacagctg
gacgtggtgatcctcgaagtgggcctcggtggacgtcttgacgccaccaatatggtcgat
gccgatgtcgcggtggtcaccagcattgcgctcgatcataccgactggctcgggccggat
cgtgaaagcatcggtcgtgaaaaagcgggtatcttccgcaccggcaaacccgcggtggtt
ggcgagccggatatgccgcacaccatcgcggaggtggcgcaggagaagggcgcgcagctg
ttacagcgcgatgtggcgtggcactacgaggctggcgcacagagctggcgttttcgcgat
gcgcagggcgagctgaacgatctgccgctgccgcaggtaccgcagccgaacgcggctacc
gcgctggccgcgctgcgtgccagcaacctggtggtaagcgagcaggcgatccgcgacggc
attgagcgggcgattttacccggtcgttttcagattgtgagcgaatcaccacgcctcatc
ctggatgtcgcgcataatcctcatgccgcaagctatcttgccggacgcttggcagcgctg
ccgaaaagcggtcgcgtgctggcggtggttggcatgctgcatgataaagacattagcgga
acgcttgcctgtctggagccggtggtcgatagctggtattgtgcccctctggaggggccg
cgcggcgcgacggcggagcagctgctggtgcacctgacgtcggggcaagcattcccggac
gtggcccaggcctggcaggcggcaatggcggaggccgacgcctgcgataccgtgctggtg
tgtggctcgttccacaccgtggcgcatgtcatggaagcgatggaagcggggagaaccggt
ggcaagtaa
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