Klebsiella michiganensis HKOPL1: J415_27325
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Entry
J415_27325 CDS
T03188
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
koy
Klebsiella michiganensis HKOPL1
Pathway
koy00260
Glycine, serine and threonine metabolism
koy00261
Monobactam biosynthesis
koy00270
Cysteine and methionine metabolism
koy00300
Lysine biosynthesis
koy01100
Metabolic pathways
koy01110
Biosynthesis of secondary metabolites
koy01120
Microbial metabolism in diverse environments
koy01230
Biosynthesis of amino acids
Module
koy_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
koy_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
koy00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
J415_27325 (thrA)
00270 Cysteine and methionine metabolism
J415_27325 (thrA)
00300 Lysine biosynthesis
J415_27325 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
J415_27325 (thrA)
Enzymes [BR:
koy01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
J415_27325 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
J415_27325 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AHW90822
LinkDB
All DBs
Position
complement(5761152..5763614)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LTNIADAERIFAELLQGLADAQPGFPHAQLKMFVEQEFAQIKHVLHGISLLGQCPDSVNA
SLICRGEKLSIAIMAGLLEARGHNVTVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGGSSD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRVMEDEFYLELKEGLLEPLSIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGIGGVGGAL
IEQIKRQQSWLKSKHIDLRVCGVANSRALLTNVHGLNLEHWRDELAEAKEAFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELLRFSGILSGSLSFIFGKLDEGVSFSAATKLA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELSDIIVEPALPAGFDASGDVDSFMA
RLPSLDDEFASRVSKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgttgaagttcggcggtacatcagtggcaaatgcagaacgttttctgcgtgtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgaccgtactgtctgccccg
gcgaagatcactaaccatctggttgcgatgatcgaaaaaaccattggcgggcaggatgcg
ctgaccaatatcgctgatgccgaacgcattttcgccgaacttctgcaaggcctcgccgat
gcccagccgggctttccgcacgctcagttgaaaatgtttgtcgagcaggagtttgcgcaa
atcaaacacgtcctgcacggtattagcctgctcggacagtgcccggatagcgtcaatgcg
tctctgatctgccggggagaaaagctctccatcgctattatggccggcttactggaagcg
cgcggtcataacgtcacggtgattaatccggttgaaaaactgcttgccgttggccattac
ctcgaatccaccgtggatatcgccgagtcgacccgccgcattgccgccagccagatcccg
gctgaccatatggtgctgatggcgggctttaccgccggtaacgaaaagggcgaactggtg
gtgctgggccgtaacggctctgactactccgcagcggtgctggccgcctgcctgcgcgcc
gactgctgtgaaatctggaccgacgttgacggcgtttatacctgcgacccgcgtcaggtg
ccggatgcgcgtttgctgaagtcgatgtcctatcaggaagcgatggagctctcctacttc
ggcgctaaagttttgcacccgcgtactatagcccccatcgcccagttccagatcccctgt
ttaatcaaaaataccggtaatccgcaggcgccgggtacgcttatcggcggcagcagcgat
gaagacgatctgccggtgaaaggtatctctaatctcaacaatatggcgatgttcaacgtc
tccgggccggggatgaaggggatggttggcatggcggcgcgcgtgttcgccactatgtcc
cgcgcgggaatctccgttgttcttatcacccagtcctcttccgaatacagcatcagcttc
tgcgtgccgcagagcgattgcgctcgggcgaagcgggtaatggaagatgaattttatctg
gagctgaaagaggggctgcttgagccgctgtcgatcatggaacgtctggcgattatttcg
gttgtcggcgatggtatgcgcaccctgcgtgggatttccgctaaattcttcgctgcgctg
gcgcgcgccaatatcaacattgtggcgattgcccagggttcttccgagcgctctatctcc
gttgtcgtgagcaacgatgatgctaccaccggcgttcgcgtgacccaccagatgctgttc
aataccgatcaggtgattgaagtgtttgtcattggcatcggcggcgtcggcggcgcgctg
atcgaacagatcaagcgccagcagagctggttgaagagtaaacatatcgacctccgcgtt
tgcggggtggctaactcgcgcgccttgctgaccaacgtacacggcctgaaccttgaacac
tggcgcgatgagctggcggaagccaaagaggcgttcaacctgggacgacttattcgtctg
gtgaaagagtaccatctgctgaacccggtgattgtcgactgtacctccagccaggcggtg
gccgatcagtacgccgatttcctgcgcgaaggtttccacgtggtgacgccgaacaaaaag
gccaatacctcatcgctggattactatcatcagctgcgtcatgccgcgagcagctcacga
cgtaagtttttatacgatactaacgtcggcgcggggctgccggtaatcgaaaacctgcaa
aatttgctgaacgccggtgatgagctgctgcgcttctccggtattctgtccggctcgctg
tcatttatcttcggtaagctggacgaaggcgtaagcttctccgcggcgacgaagctggcg
cgtgaaatgggctataccgaaccggatccgcgcgacgatctttccggcgtggatgtcgcg
cgtaagctgctaatcctcgcgcgtgaaaccgggcgtgaactggagctgtctgacattatc
gtagagccggcgctaccggcgggttttgacgccagcggcgatgtcgacagctttatggca
cgcctgccttctctggatgacgagtttgcctcgcgggtctcaaaagcgcgcgatgaaggt
aaggtcttgcgctatgtcggaaatatcgaagaggatggcacctgccgcgtgaaaatcgcc
gcggttgatggcaacgatccgctgtttaaagtgaaaaacggcgagaatgcgctggcgttc
tacagccactattaccagccgctgccgctggtgctgcgcggttatggtgcgggtaacgat
gtgacggcagctggcgttttcgccgacctgctgcgtaccctgtcatggaagttaggagtt
taa
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