Klebsiella pneumoniae blaNDM-1: FH42_10515
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Entry
FH42_10515 CDS
T03440
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00230
Purine metabolism
kpb01100
Metabolic pathways
kpb01110
Biosynthesis of secondary metabolites
Module
kpb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
FH42_10515
Enzymes [BR:
kpb01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
FH42_10515
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AIJ41129
UniProt:
A0A086IYH4
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All DBs
Position
complement(2173861..2177748)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAANLPVSAIYAEYIHFADLNAPLSADDRERLARLLQ
YGPSLSSHTPTGKLLLVTPRPGTISPWSSKATDIAHNCGLAQVVRLERGVAYYVEASTLT
EAQWAAVAAELHDRMMESVFDELEAGEKLFAHHQPTPVTSVDLLGEGRQALIDANLRLGL
ALADDEIDYLQDAFTRLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFEKTPDYVLSAYKDNAAVMEGSEVGRYFADHQTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPDRIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVTSHNGEELRGYHKPIMLAGGIGNI
RGEHVQKGEITVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFQLRDILSDEPGMSPL
EIWCNESQERYVLAVAPEQLPLFDELCRRERAPYAVIGEATAEQHLSLSDSHFNDQPIDL
PLDVLLGKTPKMTRDVQTLKAQGSALDRQPITLADAVNRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQIPVANCAVTTASLDSYYGEAMAMGERAPVALLDFAASGRLAVGEAL
TNIAATQIGELNRVKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGSEQREMTSPLSLVISAFARVEDVRHTVTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKPADVRDVAQLKGFWNAMQALVAQRKLLAYHDRSDGGLLVTLAEMAFT
GHCGVEADIAALGDDHLAALFNEELGAVIQVRAADREAVEAILAVNGLADCVHYLGKAVE
GDRFVLTAGGQTVFSESRTTLRMWWAETTWQMQRLRDNPACADQEHEAKANDADPGLNVK
LSFDINDDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLGDFHALVACGGFSYGDVLGAGEGWAKSILFNERVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSDLWPRFVRNQSDRFEARFSLVEVTQSPSLLLEGMVGSRMPIAVSHGEGQ
VEVRDSAHLAQLESKGLVALRFVDNFGKVTETYPANPNGSPNGITAVTSESGRATIMMPH
PERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattttgcgtggttcacctgcactgtcggcattccgtattaataaactgctg
gcacgatttcaggcggccaaccttccggtaagcgccatatatgccgaatatattcatttt
gccgatctgaatgccccgctgagcgctgacgatcgcgagcgcctggcgcgactgcttcag
tatggcccgagcttgagcagccataccccgaccggtaaattactgctcgtgacccctcgc
cctggcaccatctctccctggtcttctaaagctaccgatatcgctcacaactgcggtctg
gcgcaggttgtgcgtcttgagcgcggcgtggcgtattacgttgaagcctcaaccctgacc
gaagcgcagtgggccgcggtggcggcggagctgcacgaccgcatgatggagagcgtcttc
gacgagctggaagcgggcgagaagctgttcgctcaccatcagccgacgccggtcaccagc
gtcgacctgctgggcgaagggcgtcaggcgctgattgacgccaacctccgtctgggtctg
gcgctggccgacgacgaaattgactacctgcaggacgcgtttacccgcctgggacgcaac
ccgaacgatatcgagctgtatatgttcgcccaggcgaactcagagcactgtcgccacaag
attttcaacgccgactggatcatcgacggcgaacagcagccgaagtcgctgttcaaaatg
atcaaaaacacctttgaaaaaacgccggactacgtgctgtcggcctataaagataatgcc
gcggtgatggaagggtctgaagtcgggcgctatttcgccgaccatcagaccgggcgctac
gacttccatcaggagccggcgcacattctgatgaaggtggaaacccataaccacccgacg
gccatctctccatggccgggcgcggcaaccggctccggcggcgaaatccgcgatgaaggc
gccaccggccgcggcgcgaagccgaaagcgggcctggtgggcttctcggtttccaacctg
cgtatcccgggcttcgaacagccgtgggaagaagatttcggtaaaccggatcgcattgtc
accgccctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcgctgaacggctacttccgcacctatgaagagaaagtcaccagccacaat
ggcgaagagctgcgtggctaccacaaaccgatcatgctggccggcggtatcggcaacatc
cgcggtgagcacgtgcagaagggcgagattaccgtcggcgcgaagctgatcgtgctgggc
ggcccggcgatgaacatcggcctcggcggcggcgcggcgtcttctatggcctccggccag
tccgatgccgatctcgatttcgcctccgtacagcgtgacaacccggaaatggagcgccgc
tgtcaggaagtgatcgaccgctgctggcagttgggcgacgccaacccgatcctctttatc
cacgacgttggcgccggcggtctctccaacgccatgccggagctggtgagcgacggcggc
cgcggcggtaaattccagctgcgcgatattctcagcgatgagccagggatgagtccgctg
gagatctggtgtaacgaatcgcaggagcgttatgttctggcggtcgccccggagcagctg
ccgctgttcgacgaactgtgccgccgcgagcgcgcgccttatgccgttatcggcgaagcc
accgctgagcagcatctgagcctgagcgacagccactttaacgatcagccgatcgacctg
ccgctggacgtcctgctcggcaaaacgccgaaaatgacccgcgacgtgcagactctgaaa
gctcagggtagcgcgctggatcgccaaccgattacccttgccgatgcggttaaccgcgtt
ctgcatctgccgacggtggccgagaaaaccttcctcgtcaccatcggcgaccgcaccgtg
accggtatggtcgcccgcgaccagatggttggcccgtggcagatcccggtggccaactgc
gcggtgaccaccgccagcctcgacagctactatggcgaagcgatggcgatgggcgagcgc
gccccggtcgccctgctggacttcgcggcctctggccgtctggcggtcggtgaagcgctg
accaacatcgccgccacgcagattggcgagctgaaccgcgtgaagctgtcggctaactgg
atggccgccgccggccacccgggtgaagacgctggcctgtatgaggcggtgaaagcggtg
ggcgaagagctgtgcccggcgctgggcctgaccattccggtcggtaaagactcgatgtcg
atgaaaacccgctggcaggaaggcagcgagcagcgcgagatgacctccccgctgtcgctg
gtcatctctgccttcgcccgtgtcgaagatgtccgtcataccgtcacgccgcagctttcg
acggaagataacgccctgctgctgatcgacctcggtaaagggcacaacgcgctgggcgcg
acggcgctggcgcaggtctatcgccagctcggcgacaagccggctgacgtgcgcgatgtc
gcgcaactgaaaggcttctggaatgcgatgcaggccctggtggcgcagcgtaaactgctg
gcctaccacgaccgctccgacggcggtctgctggtcacgctggcggaaatggcctttacc
ggccactgcggcgtggaagcggatatcgccgcgctgggcgacgaccatctggccgcgctg
ttcaacgaagagctgggggcggtgattcaggtccgcgccgcagaccgtgaggcggtggaa
gccattctggcggttaacggcctggcggactgcgtgcattacctcggtaaagcggttgag
ggcgatcgcttcgtgctgaccgccggcggtcagacggtgttcagcgaaagccgcaccacg
ctgcgcatgtggtgggcggaaaccacctggcagatgcagcgtctgcgcgacaacccggcc
tgcgccgatcaggagcatgaggcgaaagccaatgatgccgacccgggcctcaatgtgaag
ctctcgtttgatattaacgacgacgtcgccgccccgtacattgccaccggcgcgcggccg
aaagtggccgtcctgcgcgagcagggggtgaactcccacgttgaaatggcggccgccttc
catcgtgccggctttgacgccatcgacgtgcatatgagcgacctgctggccggccggacc
ggtctgggcgatttccatgccctggtagcctgcggcggcttctcctacggcgacgtgttg
ggcgcgggcgagggctgggcgaagtcgattctgttcaacgagcgcgtgcgcgatgagttc
gcgaccttcttccatcgtccgcagacgctggcgctcggcgtgtgcaacggctgtcagatg
atgtccaacctgcgcgagctgatcccgggcagcgacctgtggccgcgctttgtgcgcaac
cagtctgaccgctttgaagcgcgctttagcctggtggaagtgacgcaaagcccatccctg
ctgctggaaggcatggttggctcacggatgccgattgcggtctcccacggcgaaggtcag
gtggaagtgcgcgacagcgcgcatctggctcagcttgagagcaaaggtctggtggcgctg
cgcttcgtggataacttcggcaaagtgaccgaaacctatccggcgaacccgaacggttcc
ccgaacggtatcaccgcggtgaccagcgaaagcgggcgcgcgaccatcatgatgccgcac
ccggaacgcgtcttccgcaccgtaagcaactcctggcacccggagaactggggcgaggat
agcccgtggatgcgtatcttccgtaacgcgcgtaaacagctgggttaa
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