KEGG   Klebsiella pneumoniae blaNDM-1: FH42_10900
Entry
FH42_10900        CDS       T03440                                 
Name
(GenBank) 2-hydroxyacid dehydrogenase
  KO
K12972  glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81]
Organism
kpb  Klebsiella pneumoniae blaNDM-1
Pathway
kpb00260  Glycine, serine and threonine metabolism
kpb00620  Pyruvate metabolism
kpb00630  Glyoxylate and dicarboxylate metabolism
kpb01100  Metabolic pathways
kpb01110  Biosynthesis of secondary metabolites
kpb01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:kpb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    FH42_10900
   00630 Glyoxylate and dicarboxylate metabolism
    FH42_10900
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    FH42_10900
Enzymes [BR:kpb01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.79  glyoxylate reductase (NADP+)
     FH42_10900
    1.1.1.81  hydroxypyruvate reductase
     FH42_10900
SSDB
Motif
Pfam: 2-Hacid_dh_C NAD_binding_2 ApbA 2-Hacid_dh F420_oxidored ThiF 3HCDH_N NAD_Gly3P_dh_N
Other DBs
NCBI-ProteinID: AIJ41199
UniProt: A0A1L5DW65
LinkDB
Position
2254091..2255023
AA seq 310 aa
MSDITIVVDCNDADFARDICAALQQFPDVTALLPHHQAVRDAQYASCWFPDPQLLTRSPG
LKLIQAASAGVDHLPPALFASEIPLCRVIDEDFRHGMFEYALWSVLWFQRHFDRALAHQR
TQTWKLYPQRAAADFHIGIMGLGEIGGYIADQLARLGYRVSGWSRSEKQLTGVTCYRGEE
ALDHFLGSLDGLINLLPLTAQTRGILAAPLFNRLPAGAVLINCGRGEHMVNDDVLAALES
GQLAGAVLDVFPQEPLPADDPLWRHPQVVITPHMASAAPAEVIARQLLENIQRQRRGLPL
KNLVNKHAGY
NT seq 933 nt   +upstreamnt  +downstreamnt
atgtctgatatcactatcgtggtggattgtaacgacgcggatttcgcccgcgatatctgc
gccgccctgcagcagtttcccgacgtcacggcgcttctgccccatcaccaggcggtgcgc
gacgcccagtacgccagctgctggttcccggacccgcagctgttgacccgttcgccgggg
ctgaagctgatccaggccgcgtccgccggggtcgatcatctgccgcccgcgctgttcgcc
agcgagatcccgctgtgccgggtgatcgatgaagattttcgccacggcatgttcgaatat
gctctgtggagcgtcctgtggtttcagcgccatttcgaccgggcgctggcccaccagcga
acccaaacctggaagctctatccccagcgcgccgccgccgacttccatatcggcattatg
ggtctgggcgaaattggcggctatatcgctgaccagctggcccgcctcggctatcgggtc
tccggctggtcgcgcagtgaaaagcagctgactggtgtcacctgctatcgcggcgaggag
gcgctcgaccactttcttgggtcgcttgacgggctgattaacctcctgccgctcaccgcg
cagacccgaggtatccttgccgcgccgctgttcaaccggctacccgccggagcggtgttg
atcaattgcggccgcggggagcatatggtcaatgacgatgtgctggcggcgctggagagc
ggccagctcgccggggcggtgctcgacgtcttcccgcaggagccattgccggcggacgat
ccgctgtggcgccatccgcaggtggtcatcaccccgcatatggcctctgcggcccctgcc
gaggtgatcgcccgccagttgctggagaacattcagcgccagcgccgcgggctgccgctg
aagaacctggtcaataagcacgccggttactga

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