Klebsiella pneumoniae blaNDM-1: FH42_17990
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Entry
FH42_17990 CDS
T03440
Name
(GenBank) 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
KO
K00549
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [EC:
2.1.1.14
]
Organism
kpb
Klebsiella pneumoniae blaNDM-1
Pathway
kpb00270
Cysteine and methionine metabolism
kpb00450
Selenocompound metabolism
kpb01100
Metabolic pathways
kpb01110
Biosynthesis of secondary metabolites
kpb01230
Biosynthesis of amino acids
Module
kpb_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:
kpb00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
FH42_17990
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
FH42_17990
Enzymes [BR:
kpb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.14 5-methyltetrahydropteroyltriglutamate---homocysteine S-methyltransferase
FH42_17990
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GFIT
Motif
Pfam:
Meth_synt_2
Meth_synt_1
Motif
Other DBs
NCBI-ProteinID:
AIJ42550
UniProt:
A0A210UIR8
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Position
3698817..3701081
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AA seq
754 aa
AA seq
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MTIINHTLGFPRVGLRRELKKAQESYWAGNATREELLAVGRELRARHWEQQKQAGVDLLP
VGDFAWYDHVLTTSLLLGNVPARHQNKDGSIDIDTLFRIGRGRAPTGEPAAAAEMTKWFN
TNYHYMVPEFVKGQQFKLSWTQLLDEVDEALALGHKIKPVLLGPVTYLWLGKVKGEPFDR
LTLLNAILPVYQQVLAELAKRGIDWVQIDEPALVLELPPAWLEAFQPAYDALQGQVKLLL
TTYFEGVSDNLATIAALPVQGLHVDLVHGKDDVAELHNRLPADWLLSAGLINGRNVWRAD
LTEKYAQIKDLVGKRELWVASSCSLLHSPIDLSVETRLDAEVKSWFAFALQKCGELALLR
DALNSGDTAAITEWSAPIQARRHSTRVHNAEVEKRLAAITAQDSQRASPYEVRAQAQRQR
FNLPKWPTTTIGSFPQTTEIRGLRLDFKKGNLDASHYRTGIAEHIKQAIVEQERLGLDVL
VHGEAERNDMVEYFGEHLDGFIFTQNGWVQSYGSRCVKPPVVIGDVSRPQAITVDWAKYA
QSLTDKPVKGMLTGPVTILCWSFPREDVSRETIAKQIALALRDEVADLEAAGIGIIQIDE
PALREGLPLKRSDWDAYLQWGVEAFRLNAAVAKDDTQIHTHMCYCEFNDIMDSIAALDAD
VITIETSRSDMELLESFEAFEYPNEIGPGVYDIHSPNVPSVEWIEALLKKAAQRIPVERL
WVNPDCGLKTRGWPETRAALANMVQAARNLRQSA
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atgacaattattaaccacaccctcggttttcctcgcgttggcctgcgccgcgagctgaaa
aaagcgcaagagagctactgggcgggcaacgccactcgcgaggaactgctggcggtaggc
cgtgagctgcgcgcccgtcactgggagcagcagaaacaggcgggcgttgatctgctgccg
gtgggggatttcgcctggtacgaccatgttctgactaccagcctgctgcttggcaacgtg
ccggctcgtcatcagaacaaagacggatccatcgacatcgataccctgttccgcattggc
cgcggccgcgcgccgactggcgaaccggccgctgctgcggaaatgaccaaatggtttaac
accaactatcactatatggtgccggagttcgtgaagggccagcagttcaaactgagctgg
acccaactgctggatgaagtcgacgaagcgctggcgctgggccacaagatcaagcccgtg
ctgctggggccggtaacttatctgtggctgggtaaagtgaaaggtgaaccgtttgaccgc
ctgaccctgctgaatgccatcctgccggtttaccagcaggtgctggccgaactggcgaag
cgcggcatcgattgggtgcagattgatgaaccggcgctggtgctggagctgccgccagcg
tggctggaggcctttcaaccggcttatgacgccctgcagggccaggtgaagctgctgctg
actacctattttgaaggcgttagcgacaatctcgcgaccattgctgcgctaccggtccag
gggctgcacgtcgatctggtgcacggcaaagatgatgttgccgaactgcacaaccgcctg
ccggccgactggctgctgtccgcgggcttgatcaatgggcgtaacgtctggcgcgccgat
ctcaccgaaaagtatgcgcaaattaaagacctcgtcggtaagcgcgagctatgggtcgcg
tcatcctgctctctgctgcatagcccgatcgatctaagcgtggagacgcgccttgatgcg
gaagtgaagagctggtttgccttcgcgctgcagaaatgcggtgagctggcgctgctgcgc
gatgcgctgaacagcggcgatacagcggcgattaccgagtggagcgcgccaatccaggcc
cgtcgccattcgacccgcgtgcacaacgcggaggtggaaaaacggctggcggcgatcact
gctcaggacagccagcgcgccagcccctatgaggttcgcgcgcaggcacagcgccagcgc
tttaacctgccgaaatggccgaccaccaccatcgggtcattcccgcaaacgaccgagatc
cgcggcctgcgcctggacttcaaaaagggtaaccttgacgccagtcattatcggacgggg
attgcggaacatattaagcaggcgatcgtcgagcaggagcggttaggtttagacgtactg
gtgcacggggaggccgagcggaacgacatggtggaatacttcggcgaacatctggacggt
tttatcttcacgcaaaacggctgggtgcagagctatggttcccgctgcgtgaagccgccg
gtggtgatcggcgacgtcagccgtccgcaggcgatcaccgtcgactgggcgaagtacgcg
cagtcgctgaccgacaagccggtgaaagggatgctcactggaccggtgaccattctgtgc
tggtccttcccgcgggaggatgtcagccgtgaaaccatcgcgaaacagattgcgctggcc
ctgcgtgatgaagtggcggatctggaggcggcggggatcggcatcatccagattgatgag
ccggcgctgcgcgaagggttaccgctgaagcgcagcgactgggatgcctatctgcagtgg
ggtgtggaagccttccgccttaatgctgcggtcgccaaagacgacacgcagatccatact
cacatgtgctattgcgagttcaatgacatcatggactccattgccgcgctggacgctgac
gtgatcaccattgaaacctcgcggtccgatatggagctgctggagtcgttcgaagcgttc
gagtaccccaatgagatcgggccgggagtatatgatattcactcgccaaacgtgccgagc
gtggagtggatcgaagcgctgctgaagaaagctgcgcagcgtatcccggtggagcgactg
tgggttaacccggactgcggcctgaaaactcgcggctggccggaaacccgcgccgcgctg
gcgaatatggtgcaagcggcgcgaaatctgcgccagtccgcctaa
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