Klebsiella pneumoniae subsp. pneumoniae KPNIH10: KPNIH10_00630
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Entry
KPNIH10_00630 CDS
T03788
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
kpc
Klebsiella pneumoniae subsp. pneumoniae KPNIH10
Pathway
kpc00290
Valine, leucine and isoleucine biosynthesis
kpc00770
Pantothenate and CoA biosynthesis
kpc01100
Metabolic pathways
kpc01110
Biosynthesis of secondary metabolites
kpc01210
2-Oxocarboxylic acid metabolism
kpc01230
Biosynthesis of amino acids
Module
kpc_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
kpc_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
kpc00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPNIH10_00630
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
KPNIH10_00630
Enzymes [BR:
kpc01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
KPNIH10_00630
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD
Motif
Other DBs
NCBI-ProteinID:
AIA34485
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Position
132304..134154
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDEQ
SNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKELFLNAGKRIV
ELTKRYYEQDDASALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNREVKNVLGLTLPQT
LEQYDVMVTQDDAVKKMFRAGPAGIRTTQAFSQDCRWDTLDDDRAEGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGNIAL
IEDGDMIAIDIPNRSIQLQLSDAEIAARREAQEARGDQAWTPKNRQRQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccacacatggccgcaatatggcgggcgcccgcgcg
ttgtggcgcgcaaccggaatgaccgatgccgatttcggcaaaccgattatcgccgtcgtt
aactcctttacccagtttgtccccgggcacgtgcacctgcgcgatctcggcaaactggtt
gccgagcagattgaagccgccggtggcgtggccaaagaattcaacaccatcgcagtggat
gatgggatcgctatgggccacgggggtatgctctattcactgccatcccgcgagctgatc
gccgactcggtggagtatatggttaacgcccactgcgctgatgccatggtttgtatctcc
aactgcgacaaaatcaccccggggatgctgatggcctccctgcgtttgaatattccggtg
atctttgtttccggcggcccgatggaagccgggaagaccaagctgtcagataaaatcatc
aagcttgacctggtggatgcgatgattcagggggcggatccgaaagtgtccgacgagcag
agtaatcaggtggaacgctccgcctgcccgacctgcggctcctgttccgggatgttcacg
gcgaactccatgaactgcctgaccgaagcgctgggcctgtcacaaccgggcaacggctct
ctgctggcgacccacgccgatcgtaaggagctgttcctaaacgccgggaaacgtatcgtg
gagctgaccaaacgctattacgagcaggatgacgcttccgcgctgccgcgcaatatcgcc
agcaaggcggcctttgagaacgctatgacgctggatatcgccatgggcggctccaccaat
accgttctgcacctgctggcggcggcgcaggaagctgaaatcgacttcaccatgagcgat
atcgataagctctcccgcaaagtgccgcagctgtgtaaggtggcgccgagcacgcagaaa
taccatatggaagatgtgcatcgcgccggcggcgtgctgggcattctgggcgagctggac
cgcgccgggctgctgaatcgcgaggtcaaaaacgtccttggcctgacgctgccgcagacc
ctggaacagtacgatgtgatggtgacccaggacgacgcggtgaaaaaaatgttccgcgcc
ggcccggcgggcattcgtaccacccaggcgttctcgcaagactgccgctgggataccctg
gatgacgatcgcgccgaaggctgtatccgttctctggaacacgcttacagcaaggacggc
ggcctggcggtgctgtacggcaatttcgcggaaaacggttgtatcgtgaaaaccgccggc
gtggacgacagcatcctgaaatttaccggtccggcgaaagtatatgagagccaggacgat
gcagttgaggctatcctcggcggtaaagtcgtggaaggcgacgtcgtggtgatccgctac
gaagggccgaaaggcgggccggggatgcaggaaatgctttaccccaccagcttcctgaag
tcgatggggctgggcaaagcgtgcgcgctgatcaccgatggccgtttctccggcggcacc
tcagggctctctatcggccacgtctctccggaagcggcgagcggcggcaacattgcgctc
attgaagatggcgacatgatcgcgattgatattccgaaccgcagcatccagctgcagctg
agcgatgcggaaattgcggcgcgtcgtgaagcccaggaagcgcgtggcgaccaggcgtgg
acgccgaagaatcgccagcgtcaggtctcctttgctcttcgcgcctacgccagcctggcg
accagcgccgacaaaggcgcggtacgcgataaatccaagctgggtggctaa
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