Klebsiella pneumoniae subsp. pneumoniae KPNIH10: KPNIH10_20375
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Entry
KPNIH10_20375 CDS
T03788
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpc
Klebsiella pneumoniae subsp. pneumoniae KPNIH10
Pathway
kpc00290
Valine, leucine and isoleucine biosynthesis
kpc00620
Pyruvate metabolism
kpc01100
Metabolic pathways
kpc01110
Biosynthesis of secondary metabolites
kpc01210
2-Oxocarboxylic acid metabolism
kpc01230
Biosynthesis of amino acids
Module
kpc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPNIH10_20375
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPNIH10_20375
Enzymes [BR:
kpc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPNIH10_20375
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AIA38220
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Position
4179837..4181513
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AA seq
558 aa
AA seq
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MLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSARKLQFWDL
LLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILRTFEALRGA
RRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQCEQQPETRWQYEYSPETFC
FTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHFSRRSEVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGIDPELR
FEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGDPWQMPYL
PIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQATDSDGKE
MTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQGQGNGLL
SAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGIDNDVARAS
LQALCNALSAADQAGGRK
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgctgagccatcctgctgaaaagtaccgtccctatccgccgatcgccctgcctgaccgc
cgctggccagaccggcaaatcagtcacgccccgcgctggctctcgactgacctgcgcgac
ggcaaccaggcgctggcggagcccatggacagcgcccgcaaactgcagttctgggatctg
ctgctggagtgcggctttaaagagattgaagtcgccttcccttccgcctcacaaaccgat
ttcaactttgtccgccagctgattgacgaacagcgcatcccggaggatgtcaccatccag
gtgctgacccaggcgcgagacccgctgatcctgcgcacctttgaggcgctgcgcggcgcc
cgccgggctaccgtccacctctacaatgccaccgcgccgctgttccgcgagctggttttc
ggcatggacaaggccgaggtgatcgccctcgcgacccgcgccacccggcttatccgtcag
cagtgcgaacagcagccggagacccgctggcaatatgaatattcgcctgaaaccttctgc
ttcaccgagcccgagtttgcgcttgagatttgcgaagcggtggcggatgtctggcagccc
tgcgccgagcgaccgatgatcgtcaatctgccggcgacggtggaagtcaacacccccaac
gtctatgccgatcagatcgagtatttttgccgccacttctcccgccgcagcgaggtctgc
atcagcgtgcacccgcataacgatcgcggcaccggcgtcgccagcgccgagctggcggtg
atggccggcgccgatcgggtagaaggctgcctgtttggcaacggcgaacgcaccggcaac
gtctgtctggtgactttggcgatgaacctctacagccagggcatcgaccctgagcttcgc
ttcgagcagatgaaccgggtggtggaggtggtggaaaactgcaaccagatccccgttcac
ccgcgccacccgtgggcgggaagtctggcttacaccgccttctccggctcccatcaggat
gcgatcaaaaaagggtttgatgcccgtcagcctggcgatccgtggcagatgccctacctg
cccattgacccgcaggatataggctgcagctatgaggcggtgatccgcgtcaacagccag
tcggggaagagcggcagcgcctggcttatcgaacaaaatcatggtctgaaactgccccgc
gggctgcagcaggacttcagccagcacgttcagcaggccaccgatagcgacggcaaagag
atgacccaccatgcgctgtggcagctgttccgcacgcgctacgggctgcaggcgcagccg
gcgctgacgctgctcgattatcagagcgccagccagcaggatggccagctttccctgcag
gcaacgctgcgtcaccacggcgaaacccgacgcctgcagggccagggcaacggcctgctc
tccgccgcagccagcgggctcagcgcgctgtttcggcagccgtttatgatcaaggactat
catgagcatacgctcggcgcgcgcagcgacagccggtcggtggcctatatccgctgcgtt
tttccgcaaggagaaagctactggggcgtgggtatcgataatgacgtggcgcgcgcctcg
ctgcaggcgctgtgcaatgcgctcagcgccgccgatcaggccgggggacgaaaatag
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