Kangiella profundi: CW740_03705
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Entry
CW740_03705 CDS
T05254
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
kpd
Kangiella profundi
Pathway
kpd00230
Purine metabolism
kpd01100
Metabolic pathways
kpd01110
Biosynthesis of secondary metabolites
Module
kpd_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
kpd00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
CW740_03705
Enzymes [BR:
kpd01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
CW740_03705
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Paralog
Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AUD78400
UniProt:
A0A2K9A6N8
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Position
771168..775076
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AA seq
1302 aa
AA seq
DB search
MLILRGNPAFSNFQKAHLLKEASSISSQVIDIYGEYVHYVDTNSELADEELKILERLLEY
GPSRPASEHTGQRLIVVPRPGTISPWSSKATNIAQNCSLDKVERIERAVAVYFKTKDGAE
LDADVVAQLKPLIHDRMTQSVFTEHSQAEVLFEQHQPKPLAHVDILGGGRNALVKANTDI
GLALAEDEIDYLVESFTKLGRNPSDVELMMFAQANSEHCRHKIFNASWTIDGIEKEMSLF
KMIKNTYQVNSEGVLSAYKDNAAVFEGFTAHRFFANAETNEYQYHLEPVHVLCKVETHNH
PTCISPYPGASTGSGGEIRDEGATGIGGKPKVGLTGFTVSNLKLPGYIQPWETDYGKPER
IVTALDIMLEGPIGGASFNNEFGRPAVNGYFRTFEEEFDFEYGKEVRGYHKPIMIAGGMG
NIREQHVEKKEIKPGYKVIVLGGPAMLIGLGGGAASSMASGSSQEDLDFASVQRDNPEME
RRCQEVIDRCWAMGEKNPIEFIHDVGAGGLSNAIPELVHDGERGGKFELRRVPNAEKGMA
PVEIWCNEAQERYVLAVSPDNLSKFEEICGRERCPFAVVGEATEELHLELNDQHFDNKPV
DLPMDILFGKPPKMHREATTLAAPSTALPQVDDINEAVDRILALPAVADKTFLITIGDRT
VGGMVSRDQMVGPWQVPVADCAVTTSTHNSYTGEAMAMGERTPAALLDSAASARMAVGEA
VTNIAAAKIDDIKKIRLSANWMAAAGAPGEDVNLYKAVEAVGMQLCPELGITIPVGKDSM
SMKTVWEDNGEQKSVTAPLSLIITAFAPVTDVRKSLTPQLRTDKDGAPLETELLLLDLGR
GKNRLGATAFTQVYKLLGTEPANVDSSDDLRNFFNAVQALNHNDLVHAYHDRSDGGLLAT
LVEMGFAGNCGVSVDLSELNGTAEEILFNEELGAVLQVPADKRDQVEAILAEYQVNEFAH
FIGEPAETKTFSVTKDGNDVISRDMKDLRAIWSELTYRMQAMRDNPECAQQEYDSKLDLD
NPGIKPVATYNVDENIAKPLISSGARPRVAVLREQGVNSQLEMAAAFTKAGFECIDVHMS
DILSGRVSLQDFTGAVACGGFSYGDVLGAGEGWAKSILFNSRARDEFEAFFNRPDTFSLG
ICNGCQMMSNLKELIPGADHWPHFVRNQSAQFEARFAMVEVAKSPSLFMTGMEGSRLPIA
VSHGEGRAEFKSEELAKQVNESGLITARYINNYGDIADTYPANPNGSPFGITGLTTTDGR
VTIMMPHPERVARTVQNSWRPDEWREDGAWQRMFYNARLSIG
NT seq
3909 nt
NT seq
+upstream
nt +downstream
nt
atgctcatattacgcggtaaccctgccttttctaattttcaaaaagcacatttactcaaa
gaagcgtcatctatcagttcgcaagttattgatatttatggtgaatacgtacactacgtg
gataccaacagcgagttggctgatgaagaattgaagattcttgaacgattattggaatac
ggcccaagccgaccagccagtgagcatactgggcagcgcttgattgtggtaccacgccca
ggaaccatttcgccatggtcttcgaaagcaaccaacatcgcgcaaaactgtagtctggac
aaagttgagcgtatcgagcgtgcagttgcggtctatttcaagactaaagatggcgctgaa
ttggatgctgatgtggttgctcaactaaagccacttattcatgaccgcatgactcagtcg
gtattcactgagcacagtcaggcggaagttttatttgaacagcaccagccgaaacctttg
gctcatgtcgatattttaggtggtggccgtaatgcactggtcaaagccaacactgacatt
ggtctggctctggcggaagacgaaattgattatctggtagagagttttactaaattgggt
cgtaatccatcggacgttgagctgatgatgttcgcccaggcaaactctgagcactgtcgc
cacaagatttttaatgcatcttggactattgatggcattgagaaagagatgtcattgttc
aagatgatcaaaaacacctatcaggttaactctgaaggtgtgctgtcagcttataaagat
aatgctgccgtatttgaaggctttaccgcgcatcgtttcttcgccaacgcggaaaccaat
gaataccaatatcacttagagcctgttcacgtactgtgtaaggtcgaaacccataaccac
ccaacctgtatttcgccatacccaggtgcttctactggctctggcggtgaaattcgtgat
gaaggcgcaaccggtattggtggcaaaccaaaagttggcttgactggctttactgtttca
aaccttaaactacccggttatatccagccttgggaaacggattacggtaagcctgagcgt
atcgttactgcattggatattatgcttgaaggcccgattggtggcgccagcttcaataac
gagtttggtcgtccggcagtgaacggttatttccgtactttcgaagaagaattcgacttt
gagtacggaaaggaagtacgcggttaccacaagccaattatgattgcaggcggtatgggt
aacatccgtgagcagcatgttgagaaaaaagaaattaagccaggttacaaagtgattgta
ctgggtggtccagcgatgttgattggtcttggcggtggtgctgcatcatcgatggcctcc
ggttccagtcaggaagatttagattttgcttcggtacagcgtgacaatcctgaaatggag
cgtcgttgtcaggaagtgatagaccgttgctgggcaatgggtgagaaaaacccaatcgaa
tttattcatgacgttggcgcgggcggcttgtcgaacgcgattccagaattagtacatgat
ggcgagcgcggcggtaagttcgaattacgccgtgtgccaaatgctgaaaaaggcatggcg
cctgttgaaatctggtgtaacgaagcacaggaacgttatgtcttagcggtatctcctgac
aacctttcaaagttcgaagaaatctgtggtcgtgagcgttgcccatttgcagtggttggc
gaagcgacagaagaactacaccttgagctaaacgatcaacactttgataacaaacctgtg
gatttaccaatggatattctattcggtaagccaccaaagatgcatcgtgaagcgactacg
ttggcagcaccgtcaacagcacttcctcaagttgatgacatcaatgaagccgttgaccgt
attctggcgctaccagcggttgcggataaaactttcctgattacgattggcgaccgtacc
gttggtggtatggtgtcgcgcgatcagatggttggcccatggcaggttccagtggctgac
tgtgcggtaactacatcaactcataacagctacactggcgaagccatggcgatgggtgaa
cgtactcctgcagcattgcttgatagtgcggcttctgcgcgtatggcagttggtgaagcg
gttaccaatattgctgctgcaaagattgatgacattaaaaagattcgcctttcggcaaac
tggatggccgctgccggcgctccgggcgaagatgtgaatctttataaagctgttgaagca
gttggcatgcagttatgtccagagcttggtatcactatcccagttggtaaagactcaatg
tctatgaaaaccgtttgggaagacaatggcgaacaaaagagtgttactgcacctctttca
ttgattatcaccgcatttgcaccggtaactgatgtacgtaagagtttgacgcctcagttg
cgcacagataaagacggcgctccattagagactgaactattactgttagatcttggtcgc
ggcaaaaaccgccttggtgcaacagccttcactcaggtctataaattacttggtacagag
ccagccaacgttgactcaagtgatgatcttcgcaacttctttaacgccgttcaggcgctg
aatcacaacgatctagttcatgcctaccacgatcgttcagatggtggtttattagcaacc
ttggttgaaatgggctttgccggaaactgtggtgtaagcgtggatttgtcagagcttaat
ggcacagcagaagagattctgtttaacgaagaactgggcgccgtgttgcaggttcctgct
gataaacgcgatcaggttgaagctattctggcagagtatcaggtcaatgaatttgcacac
ttcattggtgagccagcagaaactaaaacattcagcgtcaccaaagacggtaacgacgtt
atttcgcgtgacatgaaagacttgcgtgccatctggtcagaactgacctaccgcatgcag
gcaatgcgcgataacccagaatgcgcgcaacaggaatacgacagcaagcttgatctggat
aacccaggtatcaaacctgtagcaacttataacgttgatgaaaacatcgctaagcctctt
atctcatctggcgcacgcccacgtgttgcagtgttaagagagcagggtgtaaacagccag
ctagaaatggcggctgcgttcaccaaggcaggattcgagtgtatcgacgttcacatgagc
gacatcctgtcaggacgtgtgagcttacaagatttcaccggcgcagttgcatgtggtggt
ttctcatacggtgacgtactgggtgcaggtgaaggctgggcaaaatcgattctcttcaac
tcacgcgcgcgtgatgaattcgaagccttcttcaatcgtcctgataccttcagcttaggt
atctgtaacggttgtcagatgatgtcaaacctcaaggaattgatccctggcgcagatcat
tggccacacttcgtgcgcaaccagtcagcacaattcgaagcgcgtttcgctatggttgaa
gtggcaaaatcaccatcactattcatgaccggcatggaaggctcgcgcctaccaatcgct
gtctcacatggtgaaggccgtgcagaattcaaatctgaagaactggcaaaacaagtcaac
gagtcaggtttaatcaccgcacgttacatcaacaactacggcgatattgcagacacttat
ccagccaatccaaatggctcaccattcggtatcaccggcctcactacaactgacggtcga
gtcactatcatgatgcctcatccagagcgcgtagcgcgtacggtgcagaattcatggaga
ccggatgagtggagagaggatggggcttggcagaggatgttctataacgcccgtctttca
atcggttaa
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