Klebsiella pneumoniae subsp. pneumoniae KPNIH24: KPNIH24_08320
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Entry
KPNIH24_08320 CDS
T03369
Name
(GenBank) glutamate--cysteine ligase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
kph
Klebsiella pneumoniae subsp. pneumoniae KPNIH24
Pathway
kph00270
Cysteine and methionine metabolism
kph00480
Glutathione metabolism
kph01100
Metabolic pathways
kph01240
Biosynthesis of cofactors
Module
kph_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
kph00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
KPNIH24_08320
09106 Metabolism of other amino acids
00480 Glutathione metabolism
KPNIH24_08320
Enzymes [BR:
kph01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
KPNIH24_08320
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GFIT
Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
AID95232
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Position
1707984..1709540
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALQGIQRGLERETLRVNADGTLATTGHPPALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDVHRYTARQLGDERMWPLSMPCYIAPGQDIELAQYG
TSNVGRLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVEDAESGKEAISAGY
FRSIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEETGNGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYAKIGLQKDGKYLQINSNILQIENELY
APIRPKRVTRRGETPSDALLRGGIEYIEVRSLDINPFSPIGVDAQQVRFLDLFMVWCALA
DAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCESAQFPLAQVGKDLFRDLRRVAQTL
DSIHGGQAYQQVCDELLACFDDPELTFSARILRSMIEEGIGGTGRALADRYRTQLREEPL
EILSEDDFIAERDASVARQKKVEAEDSEPFEALLARHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatccgcaggctctgcag
ggtattcaacgtggtctggagcgggaaacgctgcgcgtgaacgcagacggcacccttgca
acgaccggtcaccctccggcgttaggctcagcgctaacgcataaatggattaccaccgat
tttgccgaagctttacttgagttcattacgccagtagatggcgatattgagcatatgctg
acctttatgcgcgatgtccatcgctataccgcgcgtcagcttggcgacgagcggatgtgg
ccgctgagcatgccatgctatatcgcccccggtcaggatattgagctggcgcagtacggc
acctctaacgtggggcgcctgaaaacgctatatcgcgaggggctgaagaaccgctatggc
gcgctgatgcagactatctccggcgtgcactataacttctccctaccgatggccttctgg
caggcaaaatgtggtgtggaagatgccgagagtggtaaagaggccatttcggcgggctat
ttccgctcaattcgtaactactatcgctttggctgggtgatcccctatctgtttggcgcc
tcgccggcgatttgctcctcattcctgcaaggcaaaccgacaacgctgccctttgaggaa
acgggcaacggcatgtattacctgccgtatgccacctcgctgcgcctcagcgaccttggt
tataccaataagtcgcaaagcaatctcggaattacgtttaacgatctgcacgagtatgtg
gcaggattgaagcgggcgattaaaacgccgtcggaagagtacgccaaaatcgggctgcag
aaagacggcaagtatctgcagatcaacagcaacattctgcagattgaaaatgaactttat
gcgccgatccgcccgaaacgcgtcacccgtcggggcgaaaccccgtccgatgcgctgttg
cgcggtggtattgagtatatcgaagtgcgttcgctggatatcaatccgttctcgccgatc
ggcgttgacgcccagcaggtgcgtttcctcgacctgtttatggtctggtgcgcgctggcc
gacgcgccggagatgagcagcgatgagctgctgtgcacccgcaccaactggaatcgggtt
attctggaagggcgtaagccgggcttaacgctggggattggctgcgaaagcgcgcagttc
ccgctggctcaggtgggcaaagatctgttccgcgatttacgccgcgtggcgcagaccctg
gacagtatccacggtggccaggcatatcagcaggtctgcgacgagctgctggcctgcttt
gacgatccggaattaaccttctcagcccgcattctgcgttctatgattgaagaaggcatt
ggcggtaccggccgtgcgcttgccgatcgttaccggacgcagctgcgcgaagagccgctg
gagatcctgagcgaagacgattttatcgccgagcgcgacgcgtcggtggcgcgacagaag
aaagtggaagctgaagacagcgagccgtttgaggcgctgctggcgcggcacgcgtag
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