Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_04388
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Entry
KPN_04388 CDS
T00566
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
kpn
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00230
Purine metabolism
kpn00670
One carbon pool by folate
kpn01100
Metabolic pathways
kpn01110
Biosynthesis of secondary metabolites
Module
kpn_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
kpn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
KPN_04388 (purH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
KPN_04388 (purH)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
kpn04147
]
KPN_04388 (purH)
Enzymes [BR:
kpn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
KPN_04388 (purH)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
KPN_04388 (purH)
Exosome [BR:
kpn04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
KPN_04388 (purH)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Motif
Other DBs
NCBI-ProteinID:
ABR79747
UniProt:
A6TGR3
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Position
complement(4798131..4799720)
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AA seq
529 aa
AA seq
DB search
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLADKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDGIMQQHGIAPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIINEMDANEGSLTLVTRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQLQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWDTRVAGLDFKRVNGGLLVQDRDLGMVTAGELRVVSKRQPTEQELRDALFC
WKVAKFVKSNAIVYAKDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGSAMASDAFFP
FRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
NT seq
1590 nt
NT seq
+upstream
nt +downstream
nt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaggccggtatc
gtcgaattcgcgcaggcgctttccgctcgtggtgtcgagctgctgtccaccggcggcacc
gctcgcctgctggcagataaaggcctgccggttaccgaagtctctgactacaccggtttc
ccggaaatgatggatggacgcgtgaagaccctgcatccgaaagtacacggcggcatcctc
ggtcgtcgcggtcaggatgacggtatcatgcagcaacacggtatcgcgcctatcgatatg
gttgtcgtgaacctttacccgttcgcccagaccgtcgctcgtgaagggtgctcgctggaa
gacgcggtggaaaacatcgatatcggcggcccgaccatggtgcgctctgcggcgaagaac
cataaagatgtcgccatcgtggttaagagcagcgactacgacgccattattaatgagatg
gacgccaacgaaggttctctcacgctggtcacccgcttcgacctcgccattaaagccttc
gaacacaccgccgcttacgacagcatgatcgccaactacttcggcagcatggttccggcc
tatcacggcgaaagcaaagaagccgctggccgcttcccgcgtaccctgaatctgaacttc
attaagaagcaggatatgcgctacggcgaaaacagccaccagcaggcggctttctatata
gaagagaatgtaaaagaggcctccgtggcgaccgccactcagctgcagggcaaagcgctc
tcctataacaacattgccgataccgatgcggcgctggagtgtgtaaaagagttcaacgag
ccggcctgcgttatcgttaagcacgccaacccgtgcggcgttgccgtcagcaactcgatt
cttgacgcctacgatcgcgcttacaaaaccgacccaacctccgcgttcggcggcatcatc
gcctttaaccgcgagctggatgctgaaaccgcgcaggcgatcatctctcgccagttcgtc
gaagtgatcatcgcgccgtccgccagcgaagaagcgctgaaaatcaccgccgcgaagcag
aacgtccgcgtactgacctgcggccagtgggatactcgcgttgccggcctcgatttcaaa
cgcgttaacggtggtctgctggttcaggaccgcgatctcggcatggtcaccgcaggtgaa
ctgcgcgtggtcagcaaacgtcagccaaccgagcaggaactgcgcgatgcgctgttctgc
tggaaagtggcgaaattcgtcaaatccaacgccattgtgtatgccaaagataatatgacc
atcggcataggcgccggtcagatgagccgcgtctactcggcgaaaatcgccggaattaaa
gccggtgatgaaggtctggaagtgaaaggttccgccatggcctctgacgctttcttcccg
ttccgcgacggcatcgatgccgcagccgcggtaggcatcacctgcgttattcagccgggc
ggctctatccgtgacgacgaagtgattgccgccgctgacgaacacggcatcgccatgatc
ttcaccgacatgcgccacttccgccattaa
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