KEGG   Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_04388
Entry
KPN_04388         CDS       T00566                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
kpn  Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00230  Purine metabolism
kpn00670  One carbon pool by folate
kpn01100  Metabolic pathways
kpn01110  Biosynthesis of secondary metabolites
Module
kpn_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:kpn00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    KPN_04388 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    KPN_04388 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:kpn04147]
    KPN_04388 (purH)
Enzymes [BR:kpn01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     KPN_04388 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     KPN_04388 (purH)
Exosome [BR:kpn04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   KPN_04388 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: ABR79747
UniProt: A6TGR3
LinkDB
Position
complement(4798131..4799720)
AA seq 529 aa
MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLLADKGLPVTEVSDYTGF
PEMMDGRVKTLHPKVHGGILGRRGQDDGIMQQHGIAPIDMVVVNLYPFAQTVAREGCSLE
DAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIINEMDANEGSLTLVTRFDLAIKAF
EHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNLNFIKKQDMRYGENSHQQAAFYI
EENVKEASVATATQLQGKALSYNNIADTDAALECVKEFNEPACVIVKHANPCGVAVSNSI
LDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAIISRQFVEVIIAPSASEEALKITAAKQ
NVRVLTCGQWDTRVAGLDFKRVNGGLLVQDRDLGMVTAGELRVVSKRQPTEQELRDALFC
WKVAKFVKSNAIVYAKDNMTIGIGAGQMSRVYSAKIAGIKAGDEGLEVKGSAMASDAFFP
FRDGIDAAAAVGITCVIQPGGSIRDDEVIAAADEHGIAMIFTDMRHFRH
NT seq 1590 nt   +upstreamnt  +downstreamnt
atgcaacaacgtcgtccagtccgccgcgctctgctcagtgtttctgacaaggccggtatc
gtcgaattcgcgcaggcgctttccgctcgtggtgtcgagctgctgtccaccggcggcacc
gctcgcctgctggcagataaaggcctgccggttaccgaagtctctgactacaccggtttc
ccggaaatgatggatggacgcgtgaagaccctgcatccgaaagtacacggcggcatcctc
ggtcgtcgcggtcaggatgacggtatcatgcagcaacacggtatcgcgcctatcgatatg
gttgtcgtgaacctttacccgttcgcccagaccgtcgctcgtgaagggtgctcgctggaa
gacgcggtggaaaacatcgatatcggcggcccgaccatggtgcgctctgcggcgaagaac
cataaagatgtcgccatcgtggttaagagcagcgactacgacgccattattaatgagatg
gacgccaacgaaggttctctcacgctggtcacccgcttcgacctcgccattaaagccttc
gaacacaccgccgcttacgacagcatgatcgccaactacttcggcagcatggttccggcc
tatcacggcgaaagcaaagaagccgctggccgcttcccgcgtaccctgaatctgaacttc
attaagaagcaggatatgcgctacggcgaaaacagccaccagcaggcggctttctatata
gaagagaatgtaaaagaggcctccgtggcgaccgccactcagctgcagggcaaagcgctc
tcctataacaacattgccgataccgatgcggcgctggagtgtgtaaaagagttcaacgag
ccggcctgcgttatcgttaagcacgccaacccgtgcggcgttgccgtcagcaactcgatt
cttgacgcctacgatcgcgcttacaaaaccgacccaacctccgcgttcggcggcatcatc
gcctttaaccgcgagctggatgctgaaaccgcgcaggcgatcatctctcgccagttcgtc
gaagtgatcatcgcgccgtccgccagcgaagaagcgctgaaaatcaccgccgcgaagcag
aacgtccgcgtactgacctgcggccagtgggatactcgcgttgccggcctcgatttcaaa
cgcgttaacggtggtctgctggttcaggaccgcgatctcggcatggtcaccgcaggtgaa
ctgcgcgtggtcagcaaacgtcagccaaccgagcaggaactgcgcgatgcgctgttctgc
tggaaagtggcgaaattcgtcaaatccaacgccattgtgtatgccaaagataatatgacc
atcggcataggcgccggtcagatgagccgcgtctactcggcgaaaatcgccggaattaaa
gccggtgatgaaggtctggaagtgaaaggttccgccatggcctctgacgctttcttcccg
ttccgcgacggcatcgatgccgcagccgcggtaggcatcacctgcgttattcagccgggc
ggctctatccgtgacgacgaagtgattgccgccgctgacgaacacggcatcgccatgatc
ttcaccgacatgcgccacttccgccattaa

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