Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52): KPN_04787
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Entry
KPN_04787 CDS
T00566
Symbol
hpaE
Name
(GenBank) 4-hydroxyphenylacetate catabolism
KO
K00151
5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase [EC:
1.2.1.60
]
Organism
kpn
Klebsiella pneumoniae subsp. pneumoniae MGH 78578 (serotype K52)
Pathway
kpn00350
Tyrosine metabolism
kpn01100
Metabolic pathways
kpn01120
Microbial metabolism in diverse environments
kpn01220
Degradation of aromatic compounds
Module
kpn_M00533
Homoprotocatechuate degradation, homoprotocatechuate => 2-oxohept-3-enedioate
Brite
KEGG Orthology (KO) [BR:
kpn00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
KPN_04787 (hpaE)
Enzymes [BR:
kpn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.60 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
KPN_04787 (hpaE)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
ABR80133
UniProt:
A6THU9
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Position
complement(5245701..5247167)
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AA seq
488 aa
AA seq
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MKKINHWINGKNVAGADYFHTTNPATGEVLAEVASGGEAEINQAVAAAKEAFPKWANLPM
KERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIPRASHNFEFFAEVCQQMNG
KTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAPCLALGNTAVLKMSELSPLTA
DRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVRAVSFTGGTATGRNIMKNAGLKK
YSMELGGKSPVLIFEDADIERALDAALFTIFSINGERCTAGSRIFIQQSIYPEFVKRFAE
RANRLRVGDPTDPNTQIGALISQQHWEKVSGYIRLGIEEGATLLAGGADKPSDLPAHLKA
GNFLRPTVLADVDNRMRVAQEEIFGPVACLLPFKDEAEGLRLANDVEYGLASYIWTQDVS
KVLRLARGIEAGMVFVNTQNVRDLRQPFGGVKASGTGREGGEYSFEVFAEMKNVCISMGD
HPIPKWGV
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgaaaaagattaaccattggatcaacggtaaaaacgttgccggcgcagactattttcat
accaccaacccggccaccggcgaggtactggcggaagtcgcctccggcggtgaagccgaa
ataaaccaggcggtggcggcggcgaaagaggccttcccgaagtgggctaacctgccgatg
aaagagcgcgcgcgcctgatgcgccgcctgggggatctgatcgatcagaacgtcccggag
atcgcggcgatggaaaccgccgataccggcctgccgatccaccagaccaaaaacgtgttg
atcccgcgcgcctcacacaatttcgaatttttcgccgaagtatgccagcagatgaacggc
aagacctatccggtcgacgacaagatgctgaactacaccctcgtgcagccggttggcgtc
tgcgcgctggtgtcgccgtggaacgtgccgtttatgaccgccacctggaaggtggcgccg
tgcctggcgctggggaataccgcggtgctgaaaatgtccgaactgtcgccgctgaccgcc
gatcgtctgggcgagctggcgctggaagccgggatcccggctggcgtactcaatgtggtg
cagggctacggcgccaccgccggcgacgcgctggtgcgccatcatgatgtgcgcgccgtc
tccttcaccggcggcaccgccaccggccgcaacatcatgaaaaacgccggtctgaaaaag
tactccatggagctgggcggaaaatcgccggtgctgatttttgaagatgccgatatcgag
cgcgcgcttgacgccgcgctgttcaccatcttctcgatcaacggcgaacgctgcaccgcc
ggctcgcgcatctttattcagcagagtatctaccccgagttcgttaaacgcttcgccgag
cgcgccaatcgcctgcgcgtaggcgatccgaccgatccgaacacccagatcggcgcgctg
attagccagcagcactgggagaaagtgtccggctacattcgcctcggcatcgaagagggg
gccaccctgctggctggcggcgcggataaaccgtccgacctgccggcgcatctgaaagcc
ggcaacttcctgcgcccgacggtgctggcggatgtcgacaaccgtatgcgcgtcgcccag
gaagagatttttggcccggtcgcctgcctgctgccgttcaaagacgaagcggaagggctg
cgcctggcgaacgatgtggaatacggcctggcgtcgtatatctggacccaggacgtcagc
aaagtgctgcgtctggcgcgcggtattgaagccgggatggtgttcgtcaacacccagaac
gtgcgcgacctgcgtcagccgttcggcggcgtgaaggcctccggcaccggccgcgaaggc
ggcgagtacagctttgaagtgttcgccgaaatgaaaaacgtctgcatctcgatgggcgac
catccgatcccgaaatggggagtctga
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