Klebsiella pneumoniae Kp52.145: BN49_1104
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Entry
BN49_1104 CDS
T05281
Symbol
gshA
Name
(GenBank) highly similar to glutamate--cysteine ligase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6TCV4)
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
kpnk
Klebsiella pneumoniae Kp52.145
Pathway
kpnk00270
Cysteine and methionine metabolism
kpnk00480
Glutathione metabolism
kpnk01100
Metabolic pathways
kpnk01240
Biosynthesis of cofactors
Module
kpnk_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
kpnk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
BN49_1104 (gshA)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
BN49_1104 (gshA)
Enzymes [BR:
kpnk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
BN49_1104 (gshA)
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GFIT
Motif
Pfam:
Glu_cys_ligase
Motif
Other DBs
NCBI-ProteinID:
CDO12865
UniProt:
A0A0W8ACA0
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Position
1141740..1143296
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AA seq
518 aa
AA seq
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MIPDVSQALAWLEKHPQALQGIQRGLERETLRVNADGTLATTGHPPALGSALTHKWITTD
FAEALLEFITPVDGDIEHMLTFMRDVHRYTARQLGDERMWPLSMPCYIAPGQDIELAQYG
TSNVGRLKTLYREGLKNRYGALMQTISGVHYNFSLPMAFWQAKCGVEDAESGKEAISAGY
FRSIRNYYRFGWVIPYLFGASPAICSSFLQGKPTTLPFEETGNGMYYLPYATSLRLSDLG
YTNKSQSNLGITFNDLHEYVAGLKRAIKTPSEEYAKIGLQKDGKYLQINSNILQIENELY
APIRPKRVTRRGETPSDALLRGGIEYIEVRSLDINPFSPIGVDAQQVRFLDLFMVWCALA
DAPEMSSDELLCTRTNWNRVILEGRKPGLTLGIGCESAQFPLAQVGKDLFRDLRRVAQTL
DSIHGGQAYQQVCDELLACFDDPELTFSARILRSMIEEGIGGTGRALADRYRTQLREEPL
EILSEDDFIAERDASVARQKKVEAEDSEPFEALLARHA
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
ttgatcccggacgtatcacaggcgctggcctggctggaaaaacatccgcaggctctgcag
ggtattcaacgtggtctggagcgggaaacgctgcgcgtgaacgcagacggcacccttgca
acgaccggtcaccctccggcgttaggctcagcgctgacgcataaatggattaccaccgat
tttgccgaagctttacttgagttcattacgccagtagatggcgatattgagcatatgctg
acctttatgcgcgatgtccatcgctataccgcgcgtcagcttggcgacgagcggatgtgg
ccgctgagtatgccatgctatatcgcccccggtcaggatattgagctggcgcagtacggc
acctctaacgtggggcgcctgaaaacgctatatcgcgaggggctgaagaaccgctatggc
gcgctgatgcagactatctccggcgtgcactataacttctccctaccgatggccttctgg
caggcaaaatgtggtgtggaggatgccgagagtggtaaagaggccatttcggcgggctat
ttccgctcaattcgtaactactatcgctttggctgggtgatcccctatctgtttggcgcc
tcgccggcgatttgctcctcattcctgcaaggcaaaccgacaacgctgccctttgaggaa
acgggcaacggcatgtattacctgccgtatgccacctcgctgcgcctcagcgaccttggt
tataccaataagtcgcaaagcaatctcggaattacgtttaacgatctgcacgagtatgtg
gcaggattgaagcgggcgattaaaacgccgtcggaagagtacgccaaaatcgggctgcag
aaagacggcaagtatctgcagatcaacagcaacattctgcagattgaaaatgaactttat
gcgccgatccgcccgaaacgcgtcacccgtcggggcgaaaccccgtccgatgcgctgttg
cgcggtggtattgagtatatcgaagtgcgttcgctggatatcaatccgttctcgccgatc
ggcgttgacgcccagcaggtgcgtttcctcgacctgtttatggtctggtgcgcgctggcc
gacgcgccggagatgagcagcgatgagctgctgtgcacccgcaccaactggaatcgggtg
attctggaagggcgtaagccgggcttaacgctggggattggctgcgaaagcgcgcagttc
ccgctggctcaggtgggcaaagatctgttccgcgatttacgccgcgtggcgcagaccctg
gacagtatccacggtggccaggcatatcagcaggtctgcgacgagctgctggcctgcttt
gacgatccggaattaaccttctcagcccgcattctgcgttctatgattgaagaaggcatt
ggcggtaccggccgtgcgcttgccgatcgttaccggacgcagctgcgcgaagagccgctg
gagatcctgagcgaagacgattttatcgccgagcgcgacgcgtcggtggcgcgacagaag
aaagtggaagctgaagacagcgagccgtttgaggcgctgctggcgcggcacgcgtag
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