Klebsiella pneumoniae Kp52.145: BN49_1107
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Entry
BN49_1107 CDS
T05281
Symbol
leuA
Name
(GenBank) similar to 2-isopropylmalate synthase from Pseudomonas stutzeri (sp|A4VNV6)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpnk
Klebsiella pneumoniae Kp52.145
Pathway
kpnk00290
Valine, leucine and isoleucine biosynthesis
kpnk00620
Pyruvate metabolism
kpnk01100
Metabolic pathways
kpnk01110
Biosynthesis of secondary metabolites
kpnk01210
2-Oxocarboxylic acid metabolism
kpnk01230
Biosynthesis of amino acids
Module
kpnk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpnk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
BN49_1107 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
BN49_1107 (leuA)
Enzymes [BR:
kpnk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
BN49_1107 (leuA)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
GAF_PdtaS
Motif
Other DBs
NCBI-ProteinID:
CDO12868
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Position
complement(1144767..1146464)
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AA seq
565 aa
AA seq
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MTIKENTMLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSAR
KLQFWDLLLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILRT
FEALRGARRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQSEQQPETRWQYE
YSPETFCFTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHF
SRRGEVCISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQ
GIDPELRFEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGD
PWQMPYLPIAPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQA
TDSDGKEMTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQ
GQGNGLLSAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGID
NDVARASLQALCNALSAADQAGGRK
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
ctgaccattaaggagaacactatgctgagccatcctgctgaaaagtaccgtccctatccg
ccgatcgccctgcctgaccgccgctggccagaccggcaaatcagtcacgccccgcgctgg
ctgtcgactgacctgcgcgacggcaaccaggcgctggcggagcccatggacagcgcccgc
aaactgcagttctgggatctgctgctggagtgcggctttaaagagattgaagtcgccttc
ccttccgcctcacaaaccgatttcaactttgtccgccagctgattgacgaacagcgcatc
ccggaggatgtcaccatccaggtgctgacccaggcgcgagacccgctgatcctgcgcacc
tttgaggcgctgcgcggcgcccgccgggctaccgtccacctctacaatgccaccgcgccg
ctgttccgcgagctggttttcggcatggacaaggccgaggtgatcgccctcgcgacccgc
gccacccggcttatccgtcagcagtccgaacagcagccggagacccgctggcaatatgaa
tattcgcctgaaaccttctgcttcaccgagcccgagtttgcgcttgagatttgcgaagcg
gtggcggatgtctggcagccctgcgccgagcgaccgatgatcgtcaatctgccggcgacg
gtggaagtcaacacccccaacgtctatgccgatcagatcgagtatttttgccgccacttc
tcccgccgcggcgaggtctgcatcagcgtgcacccgcataacgatcgcggcaccggcgtc
gccagcgccgagctggcggtgatggccggcgccgatcgggtagaaggctgcctgtttggc
aacggcgaacgcaccggcaacgtctgtctggtgactttggcgatgaacctctacagccag
ggcatcgaccctgagcttcgcttcgagcagatgaaccgggtggtggaggtggtggaaaac
tgcaaccagatccccgttcacccgcgccacccgtgggcgggaagcctggcttacaccgcc
ttctccggctcccatcaggatgcgatcaaaaaagggtttgatgcccgtcagcctggcgat
ccgtggcagatgccctacctgcccattgccccgcaggatattggctgcagctatgaggcg
gtgatccgcgtcaacagccagtcggggaagagcggcagcgcctggcttatcgaacaaaat
catggtctgaaactgccccgcgggctgcagcaggacttcagccagcacgttcagcaggcc
accgatagcgacggcaaagagatgacccaccatgcgctgtggcagctgttccgcacgcgc
tacgggctgcaggcgcagccggcgctgacgctgctcgattatcagagcgccagccagcag
gatggccagctttccctgcaggcaacgctgcgtcaccacggcgaaacccgacgcctgcag
ggccagggcaacggcctgctctccgccgcagccagcgggctcagcgcgctgtttcggcag
ccgtttatgatcaaggactatcatgagcataccctcggcgcgcgcagcgacagccggtcg
gtggcctatatccgctgcgtttttccgcaaggagaaagctactggggcgtgggtatcgat
aatgacgtggcgcgcgcctcgctgcaggcgctgtgcaatgcgctcagcgccgccgatcag
gccgggggacgaaaatag
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