KEGG   Klebsiella pneumoniae Kp52.145: BN49_3622
Entry
BN49_3622         CDS       T05281                                 
Symbol
clbH
Name
(GenBank) highly similar to putative non-ribosomal peptide synthase from Escherichia coli F11 (tr|B3HKZ5)
  KO
K26565  colibactin biosynthesis nonribosomal peptide synthase
Organism
kpnk  Klebsiella pneumoniae Kp52.145
Pathway
kpnk01054  Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:kpnk00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01054 Nonribosomal peptide structures
    BN49_3622 (clbH)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:kpnk01008]
    BN49_3622 (clbH)
Polyketide biosynthesis proteins [BR:kpnk01008]
 Polyketide synthase (PKS)
  PKS-NRPS hybrid
   Bacterial type (modular)
    Colibactin synthetase
     BN49_3622 (clbH)
SSDB
Motif
Pfam: AMP-binding Condensation AMP-binding_C PP-binding DUF7080
Other DBs
NCBI-ProteinID: CDO15374
LinkDB
Position
complement(3787561..3792372)
AA seq 1603 aa
MKARVMEQQGIMRQLPTDDQTIVDYLYRIAGEYGEKTAVLMGDAALSYHDLNARSNQLAH
YLRGLGIGEDRVVAIRLPRGMAMLIAIFAIVKAGGAYLPLAYNAPRSRIENILSNSGAVC
LIGTDDGDRWPIPRVEIDSAAVSAMPTTDLRYRPHARQLAYIIYTSGSTGVPKGVATEHA
ALLNRIVWMQNAYPISSQDVLFQKTVYTFDVSVWEMFWWAMYGASVVLLPSGLESDPRTL
ARLIQRHRVSVVHFVPSMLNLFVEYLEMKQDPRLTASLRSVFSSGEKLTVHSVARFYQSV
AQGDLINLYGPTEAAIDVSHHRCLRGYDYDDIPIGQAIDGCRLYVLDDHGNPVADGEEGE
LYLAGIGLARGYLNNVALTDRCFTVHPTLRHLGKPERLYKTGDLVWRDGESQQIHYIGRN
DFQVKIRGLRVELGEIEAHAMRFPGVQQAVVVADQDDPDNQLIYAFVVSSVPLNLAALMD
ALSKNLPAYMLPNRLLAMSELPLSDNGKCCRKTLLDLARAYSASRVDLRETPAVRYLPLS
SAQSSMWFMQQLAPHTALYNNPTALLLEGELDRTRMDGAIRQLMSRHTLLRAMAETHNGQ
PVLAVPQCVSSQALLTIVPLPSVSDDNALQAMINQRAAHPMPLTSGTPLCRFELLTIDDD
RSVLLIHLHHIISDGWSKGVLLRELQAAYNGESLTPEPLLEYADYMEYQEEWRQSDAYQD
AMRYWQNTLAGTLPILDIPTDQPRQKVARYQGAFVAFALSANTCERVLAAARAQRVSLYN
YLLTAFVLLLHRNARQQEYIVGMPIAARLTKEQEHMIAPLVNVLPLRLPLDEAASFSELV
QTIRGILFAAFRHQRLEFTDIVRAVNVDRSAGHFPIYQCMFQLDNMPLASPTLNGVNVTP
LLLDTSASQVDISLSMQHIDGRITGTFEYDAGLYSADRIQHLVAQWRELLDEASSQPTQL
VRDLIRFTPREHAWLARHNATEVALPPVDNLLALVLPHCQQRPTQVALRHADDAMTYGEL
QQATMQMCTWLRAQGVKRGESVALQLPFCFELIIAQLAILSLGASYVPLDGNAPAARNAL
ILAQATPCMLLMAQPLESPHGLTIPWVLVPDWRSLLTEIPNLPVSVAPDALDCDAVVIFT
SGTTGQPKGVRLSQRNLVNLTASFISSYQVTHQDVLLPITSVASASFVGEVLPLLAAGGT
LVLAQKAQSLDSDALIALLASQRVTILSTTPSLSASLSVLAQSMGSLRLFLCGGEALEYE
QIAPLLPHMAVVNGYGLTESGICSTYFPVAKRREQETGALPIGRPIQNTQAYVVDAYNRL
VPPGACGELCFSGLGISPGYLDARQDPERFVELPEYPGVRVLKTGDRARWATDGMLFYLG
RQDRQVQIRGYRVELGDIESLLKQHPDIADAWVDVRRNAAATPLLVAFYCSVNGVALDAQ
QLRVWLSLRLPLHMLPLLYVPLSAMPLGVNGKIDPQCLPLVDLRQLEGPGEYVPPATELE
QRLAEIWQQLLGLERVGTTTNFFDLGGHSLLLVQMQQYIGQQCGQHVALVDLLRFTTIKR
LAEFLLAPDAAQGTTRDQTQLRAAKQRLAFGHTRWAATTDSHH
NT seq 4812 nt   +upstreamnt  +downstreamnt
ttgaaggccagagttatggaacagcaagggattatgagacagttgcccaccgacgaccaa
acgatagtcgactatttgtatcgtatcgccggagaatatggggaaaaaaccgctgtattg
atgggggacgcggcgctgagctatcacgatcttaatgcacgctctaaccaactggcgcat
tatctgcgtgggctggggatcggcgaggatcgtgtggtagctatccgcctgccgcgcggc
atggcaatgctgattgccattttcgctattgtaaaagctggtggtgcctatttaccgctg
gcgtacaatgcaccgcgcagccgcattgaaaatatactgagcaacagcggcgctgtttgt
ctgatcggtactgacgatggtgatcgctggccgattcctcgcgtcgaaatcgacagcgcg
gcggtcagtgccatgccaacgacggatctgcgttaccgaccacatgcgcggcaactggcg
tatattatttacacctccggttccaccggtgtccctaaaggggtggcgacggaacatgca
gcgctgctaaaccgaattgtctggatgcagaacgcttatcctatcagttctcaggacgtg
ctgttccagaagacggtgtacacctttgacgtctctgtctgggagatgttctggtgggcg
atgtacggcgcatctgtagtgctgttaccgtccggactggagagcgatccgcgaaccttg
gctcgactgattcagcgtcaccgcgtgtcggttgtgcactttgtcccttcgatgctgaac
ctgtttgtcgagtatctggagatgaaacaggatcctcgtttgaccgcctcattgcgatca
gtgttttccagcggtgagaaactcacggtccacagtgtggctcgcttttatcaatcggtg
gcgcagggtgatcttataaatctctatggcccgaccgaagcagcaatcgatgtcagtcat
caccgctgcctgcgcgggtacgactacgacgatatccctatcggtcaagcgattgacggt
tgccgactctatgtgctggatgaccatggtaatccggtagcagacggcgaagagggcgaa
ctgtatctcgctggtatcgggctggcacgtggctatctcaacaacgtggcgttaactgat
cgctgttttactgtacatccaactttgcgccatttagggaaaccggagcggctgtataaa
actggagatctggtgtggcgcgacggggaaagccaacaaattcattacattggccgtaat
gattttcaggttaaaattagagggttgcgcgttgaattgggagaaatcgaagcccatgcg
atgcgtttcccgggggtacagcaggcagtcgtggtggcggatcaggatgatcccgataat
cagttgatttacgcttttgtcgtcagtagcgtgccgctcaatttggcggccttaatggac
gcactgtccaaaaacttgcctgcctacatgctgccgaaccgtttgttggcaatgtcagag
ttaccactctccgacaatggcaagtgctgtcgtaaaacgttgctcgacttggcgcgggcg
tactcagccagtcgcgtcgatttacgtgaaactcccgccgtgcgctacctaccgttgtca
tcggctcaatcgtcgatgtggtttatgcaacaattggcgccgcatactgcactatacaat
aaccccaccgccttgctgcttgaaggagaactggatcgcacgcggatggacggcgcgatt
cgtcaattgatgagtcggcatactctgttacgtgctatggcggaaacccacaatggacaa
ccagtattggcggtgcctcagtgcgtatcgtcgcaggcgttgctgaccatagtgccactc
ccctcggtgagtgatgataacgcgctacaggcgatgatcaaccagcgtgcggcacacccc
atgcccttaacgtcaggcacaccgctgtgccggtttgaactgttgacgatcgatgacgat
cgtagcgtattgttgattcatctgcaccacatcatcagtgatggctggtcgaaaggcgtt
ttgttacgcgaattgcaggccgcatataacggtgaatcgctgacgccagaaccgttgttg
gagtatgccgactacatggagtaccaagaagagtggcgtcagagtgacgcctatcaggac
gcgatgcgttactggcaaaataccctggcggggacgttgccgattcttgatatccccacc
gatcaaccgcgtcagaaggtggcacgttaccaaggcgcgtttgttgccttcgcattgtct
gccaacacatgcgagcgagtgttggcggcggcgcgtgcgcagcgcgtgtcgttgtataac
tatctgctgaccgccttcgtcctcctgctgcatcgtaatgcgcgtcaacaggaatacatc
gttggtatgccgattgctgcgcggctgacgaaagaacaggagcatatgatcgcgccgctg
gtcaacgtactaccgctgcgcttacctcttgacgaagcggcatcgttttccgagttagta
cagacgatcagaggtattctgtttgccgctttcaggcaccagcgtctcgaatttaccgac
atagtgcgcgcagtgaatgtggatcgcagcgccggacatttcccaatatatcagtgcatg
ttccaactcgacaatatgcctctggcgagcccgacactaaacggtgtcaacgttacacca
ttattgttggataccagtgcatctcaggtggatatttcgctaagtatgcagcatatcgat
gggcgcatcaccggcactttcgaatacgacgctgggttatacagtgcggatcgtattcag
cacctggtggcgcagtggagagaactgctagatgaggccagcagccaacccacgcagtta
gtccgcgatttgattcgtttcacccctcgagagcacgcttggctggcgcggcacaacgcc
actgaagttgctctgccgcccgtagataacctgctggcgctagtgttaccgcactgccag
cagcgccctacacaggtggctttgcgccacgctgacgacgccatgacctatggcgaattg
caacaggccacgatgcagatgtgtacttggctgcgtgcgcaaggcgtaaaacgcggagaa
tctgtcgcactgcaactgcctttttgtttcgaattgattatcgcacaattggcgatcctc
tctttgggggcgagctatgtgccgctggatggtaacgcgccagcggcccgcaatgccctg
atcttggcgcaggcaacgccgtgcatgctgctgatggcgcaaccgctggaatcccctcat
gggctgacgataccttgggtgctagtgcctgactggcgtagcctgctgacagaaataccg
aacctgccagttagtgttgcgccagatgctttagattgcgatgcggtagtgatctttacc
tccggtactaccgggcaacccaaaggcgtccgactcagccaacgtaatctggtcaactta
accgcatcctttatatccagctatcaagtgacgcatcaggatgttctgctacccattacc
tcagtcgcgtctgctagctttgtcggggaggtactgccgctgctcgccgctggcggtacc
ttagtattggcgcaaaaagcgcagagtttggatagtgatgcgctcattgcgctgctggca
tctcagcgggtgactatcctgagcaccaccccatcgctttctgccagcctctctgtgctg
gctcagtcgatgggatcgctgcgcttgtttctgtgcggtggtgaagcgttagagtatgag
cagatagcgccgcttctgccgcacatggcagtggttaacggttatggcctgaccgaaagc
ggtatctgctcgacctactttcctgtcgcaaagcgtagggagcaagaaacgggagcattg
cccattggccgcccgattcagaacacccaagcttatgtggtggatgcatataatcgtttg
gtaccgccaggtgcctgtggagaactctgtttctctggtctgggcatttcgcccggctac
cttgatgcacgacaggatcccgagcgctttgtcgagttgccggaataccctggcgttcgg
gtgctgaaaactggcgatcgtgctcgttgggcaaccgacgggatgttgttctatctcggc
agacaagatcgccaagtgcagatccgtggataccgagttgaactgggcgacatcgaaagc
ctactgaaacagcatccggatattgctgatgcgtgggtcgatgtgcgacgcaatgcggcg
gcaacgccgctactagtggccttctattgcagcgtcaacggcgttgcgctggatgctcag
caattgcgcgtatggctcagcctgcggcttccgttgcatatgctgccgttgctctacgtg
ccgctgagcgccatgccgctaggtgtaaacggcaaaatcgatccccagtgcctgccgctg
gtcgatctgcggcagttggaagggccgggcgagtatgtccctccggcaaccgaactggaa
cagcgtctggcggagatctggcagcagttgcttggcctggagcgtgtcggcaccaccaca
aatttcttcgatctcggtggacactcacttctgctagtacagatgcagcaatacatcggg
cagcagtgcggtcagcacgtggcgttggttgacctgctgcgcttcactaccatcaaacgc
ttggcggaatttctgctggccccggacgcagcgcaagggaccacaagagatcagacacaa
ctgcgtgcggcgaagcagcgtttggcctttggtcacacgcgctgggcagccacaaccgac
agtcatcactga

DBGET integrated database retrieval system