Klebsiella pneumoniae Kp52.145: BN49_3622
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Entry
BN49_3622 CDS
T05281
Symbol
clbH
Name
(GenBank) highly similar to putative non-ribosomal peptide synthase from Escherichia coli F11 (tr|B3HKZ5)
KO
K26565
colibactin biosynthesis nonribosomal peptide synthase
Organism
kpnk
Klebsiella pneumoniae Kp52.145
Pathway
kpnk01054
Nonribosomal peptide structures
Brite
KEGG Orthology (KO) [BR:
kpnk00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01054 Nonribosomal peptide structures
BN49_3622 (clbH)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
kpnk01008
]
BN49_3622 (clbH)
Polyketide biosynthesis proteins [BR:
kpnk01008
]
Polyketide synthase (PKS)
PKS-NRPS hybrid
Bacterial type (modular)
Colibactin synthetase
BN49_3622 (clbH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
AMP-binding_C
PP-binding
DUF7080
Motif
Other DBs
NCBI-ProteinID:
CDO15374
LinkDB
All DBs
Position
complement(3787561..3792372)
Genome browser
AA seq
1603 aa
AA seq
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MKARVMEQQGIMRQLPTDDQTIVDYLYRIAGEYGEKTAVLMGDAALSYHDLNARSNQLAH
YLRGLGIGEDRVVAIRLPRGMAMLIAIFAIVKAGGAYLPLAYNAPRSRIENILSNSGAVC
LIGTDDGDRWPIPRVEIDSAAVSAMPTTDLRYRPHARQLAYIIYTSGSTGVPKGVATEHA
ALLNRIVWMQNAYPISSQDVLFQKTVYTFDVSVWEMFWWAMYGASVVLLPSGLESDPRTL
ARLIQRHRVSVVHFVPSMLNLFVEYLEMKQDPRLTASLRSVFSSGEKLTVHSVARFYQSV
AQGDLINLYGPTEAAIDVSHHRCLRGYDYDDIPIGQAIDGCRLYVLDDHGNPVADGEEGE
LYLAGIGLARGYLNNVALTDRCFTVHPTLRHLGKPERLYKTGDLVWRDGESQQIHYIGRN
DFQVKIRGLRVELGEIEAHAMRFPGVQQAVVVADQDDPDNQLIYAFVVSSVPLNLAALMD
ALSKNLPAYMLPNRLLAMSELPLSDNGKCCRKTLLDLARAYSASRVDLRETPAVRYLPLS
SAQSSMWFMQQLAPHTALYNNPTALLLEGELDRTRMDGAIRQLMSRHTLLRAMAETHNGQ
PVLAVPQCVSSQALLTIVPLPSVSDDNALQAMINQRAAHPMPLTSGTPLCRFELLTIDDD
RSVLLIHLHHIISDGWSKGVLLRELQAAYNGESLTPEPLLEYADYMEYQEEWRQSDAYQD
AMRYWQNTLAGTLPILDIPTDQPRQKVARYQGAFVAFALSANTCERVLAAARAQRVSLYN
YLLTAFVLLLHRNARQQEYIVGMPIAARLTKEQEHMIAPLVNVLPLRLPLDEAASFSELV
QTIRGILFAAFRHQRLEFTDIVRAVNVDRSAGHFPIYQCMFQLDNMPLASPTLNGVNVTP
LLLDTSASQVDISLSMQHIDGRITGTFEYDAGLYSADRIQHLVAQWRELLDEASSQPTQL
VRDLIRFTPREHAWLARHNATEVALPPVDNLLALVLPHCQQRPTQVALRHADDAMTYGEL
QQATMQMCTWLRAQGVKRGESVALQLPFCFELIIAQLAILSLGASYVPLDGNAPAARNAL
ILAQATPCMLLMAQPLESPHGLTIPWVLVPDWRSLLTEIPNLPVSVAPDALDCDAVVIFT
SGTTGQPKGVRLSQRNLVNLTASFISSYQVTHQDVLLPITSVASASFVGEVLPLLAAGGT
LVLAQKAQSLDSDALIALLASQRVTILSTTPSLSASLSVLAQSMGSLRLFLCGGEALEYE
QIAPLLPHMAVVNGYGLTESGICSTYFPVAKRREQETGALPIGRPIQNTQAYVVDAYNRL
VPPGACGELCFSGLGISPGYLDARQDPERFVELPEYPGVRVLKTGDRARWATDGMLFYLG
RQDRQVQIRGYRVELGDIESLLKQHPDIADAWVDVRRNAAATPLLVAFYCSVNGVALDAQ
QLRVWLSLRLPLHMLPLLYVPLSAMPLGVNGKIDPQCLPLVDLRQLEGPGEYVPPATELE
QRLAEIWQQLLGLERVGTTTNFFDLGGHSLLLVQMQQYIGQQCGQHVALVDLLRFTTIKR
LAEFLLAPDAAQGTTRDQTQLRAAKQRLAFGHTRWAATTDSHH
NT seq
4812 nt
NT seq
+upstream
nt +downstream
nt
ttgaaggccagagttatggaacagcaagggattatgagacagttgcccaccgacgaccaa
acgatagtcgactatttgtatcgtatcgccggagaatatggggaaaaaaccgctgtattg
atgggggacgcggcgctgagctatcacgatcttaatgcacgctctaaccaactggcgcat
tatctgcgtgggctggggatcggcgaggatcgtgtggtagctatccgcctgccgcgcggc
atggcaatgctgattgccattttcgctattgtaaaagctggtggtgcctatttaccgctg
gcgtacaatgcaccgcgcagccgcattgaaaatatactgagcaacagcggcgctgtttgt
ctgatcggtactgacgatggtgatcgctggccgattcctcgcgtcgaaatcgacagcgcg
gcggtcagtgccatgccaacgacggatctgcgttaccgaccacatgcgcggcaactggcg
tatattatttacacctccggttccaccggtgtccctaaaggggtggcgacggaacatgca
gcgctgctaaaccgaattgtctggatgcagaacgcttatcctatcagttctcaggacgtg
ctgttccagaagacggtgtacacctttgacgtctctgtctgggagatgttctggtgggcg
atgtacggcgcatctgtagtgctgttaccgtccggactggagagcgatccgcgaaccttg
gctcgactgattcagcgtcaccgcgtgtcggttgtgcactttgtcccttcgatgctgaac
ctgtttgtcgagtatctggagatgaaacaggatcctcgtttgaccgcctcattgcgatca
gtgttttccagcggtgagaaactcacggtccacagtgtggctcgcttttatcaatcggtg
gcgcagggtgatcttataaatctctatggcccgaccgaagcagcaatcgatgtcagtcat
caccgctgcctgcgcgggtacgactacgacgatatccctatcggtcaagcgattgacggt
tgccgactctatgtgctggatgaccatggtaatccggtagcagacggcgaagagggcgaa
ctgtatctcgctggtatcgggctggcacgtggctatctcaacaacgtggcgttaactgat
cgctgttttactgtacatccaactttgcgccatttagggaaaccggagcggctgtataaa
actggagatctggtgtggcgcgacggggaaagccaacaaattcattacattggccgtaat
gattttcaggttaaaattagagggttgcgcgttgaattgggagaaatcgaagcccatgcg
atgcgtttcccgggggtacagcaggcagtcgtggtggcggatcaggatgatcccgataat
cagttgatttacgcttttgtcgtcagtagcgtgccgctcaatttggcggccttaatggac
gcactgtccaaaaacttgcctgcctacatgctgccgaaccgtttgttggcaatgtcagag
ttaccactctccgacaatggcaagtgctgtcgtaaaacgttgctcgacttggcgcgggcg
tactcagccagtcgcgtcgatttacgtgaaactcccgccgtgcgctacctaccgttgtca
tcggctcaatcgtcgatgtggtttatgcaacaattggcgccgcatactgcactatacaat
aaccccaccgccttgctgcttgaaggagaactggatcgcacgcggatggacggcgcgatt
cgtcaattgatgagtcggcatactctgttacgtgctatggcggaaacccacaatggacaa
ccagtattggcggtgcctcagtgcgtatcgtcgcaggcgttgctgaccatagtgccactc
ccctcggtgagtgatgataacgcgctacaggcgatgatcaaccagcgtgcggcacacccc
atgcccttaacgtcaggcacaccgctgtgccggtttgaactgttgacgatcgatgacgat
cgtagcgtattgttgattcatctgcaccacatcatcagtgatggctggtcgaaaggcgtt
ttgttacgcgaattgcaggccgcatataacggtgaatcgctgacgccagaaccgttgttg
gagtatgccgactacatggagtaccaagaagagtggcgtcagagtgacgcctatcaggac
gcgatgcgttactggcaaaataccctggcggggacgttgccgattcttgatatccccacc
gatcaaccgcgtcagaaggtggcacgttaccaaggcgcgtttgttgccttcgcattgtct
gccaacacatgcgagcgagtgttggcggcggcgcgtgcgcagcgcgtgtcgttgtataac
tatctgctgaccgccttcgtcctcctgctgcatcgtaatgcgcgtcaacaggaatacatc
gttggtatgccgattgctgcgcggctgacgaaagaacaggagcatatgatcgcgccgctg
gtcaacgtactaccgctgcgcttacctcttgacgaagcggcatcgttttccgagttagta
cagacgatcagaggtattctgtttgccgctttcaggcaccagcgtctcgaatttaccgac
atagtgcgcgcagtgaatgtggatcgcagcgccggacatttcccaatatatcagtgcatg
ttccaactcgacaatatgcctctggcgagcccgacactaaacggtgtcaacgttacacca
ttattgttggataccagtgcatctcaggtggatatttcgctaagtatgcagcatatcgat
gggcgcatcaccggcactttcgaatacgacgctgggttatacagtgcggatcgtattcag
cacctggtggcgcagtggagagaactgctagatgaggccagcagccaacccacgcagtta
gtccgcgatttgattcgtttcacccctcgagagcacgcttggctggcgcggcacaacgcc
actgaagttgctctgccgcccgtagataacctgctggcgctagtgttaccgcactgccag
cagcgccctacacaggtggctttgcgccacgctgacgacgccatgacctatggcgaattg
caacaggccacgatgcagatgtgtacttggctgcgtgcgcaaggcgtaaaacgcggagaa
tctgtcgcactgcaactgcctttttgtttcgaattgattatcgcacaattggcgatcctc
tctttgggggcgagctatgtgccgctggatggtaacgcgccagcggcccgcaatgccctg
atcttggcgcaggcaacgccgtgcatgctgctgatggcgcaaccgctggaatcccctcat
gggctgacgataccttgggtgctagtgcctgactggcgtagcctgctgacagaaataccg
aacctgccagttagtgttgcgccagatgctttagattgcgatgcggtagtgatctttacc
tccggtactaccgggcaacccaaaggcgtccgactcagccaacgtaatctggtcaactta
accgcatcctttatatccagctatcaagtgacgcatcaggatgttctgctacccattacc
tcagtcgcgtctgctagctttgtcggggaggtactgccgctgctcgccgctggcggtacc
ttagtattggcgcaaaaagcgcagagtttggatagtgatgcgctcattgcgctgctggca
tctcagcgggtgactatcctgagcaccaccccatcgctttctgccagcctctctgtgctg
gctcagtcgatgggatcgctgcgcttgtttctgtgcggtggtgaagcgttagagtatgag
cagatagcgccgcttctgccgcacatggcagtggttaacggttatggcctgaccgaaagc
ggtatctgctcgacctactttcctgtcgcaaagcgtagggagcaagaaacgggagcattg
cccattggccgcccgattcagaacacccaagcttatgtggtggatgcatataatcgtttg
gtaccgccaggtgcctgtggagaactctgtttctctggtctgggcatttcgcccggctac
cttgatgcacgacaggatcccgagcgctttgtcgagttgccggaataccctggcgttcgg
gtgctgaaaactggcgatcgtgctcgttgggcaaccgacgggatgttgttctatctcggc
agacaagatcgccaagtgcagatccgtggataccgagttgaactgggcgacatcgaaagc
ctactgaaacagcatccggatattgctgatgcgtgggtcgatgtgcgacgcaatgcggcg
gcaacgccgctactagtggccttctattgcagcgtcaacggcgttgcgctggatgctcag
caattgcgcgtatggctcagcctgcggcttccgttgcatatgctgccgttgctctacgtg
ccgctgagcgccatgccgctaggtgtaaacggcaaaatcgatccccagtgcctgccgctg
gtcgatctgcggcagttggaagggccgggcgagtatgtccctccggcaaccgaactggaa
cagcgtctggcggagatctggcagcagttgcttggcctggagcgtgtcggcaccaccaca
aatttcttcgatctcggtggacactcacttctgctagtacagatgcagcaatacatcggg
cagcagtgcggtcagcacgtggcgttggttgacctgctgcgcttcactaccatcaaacgc
ttggcggaatttctgctggccccggacgcagcgcaagggaccacaagagatcagacacaa
ctgcgtgcggcgaagcagcgtttggcctttggtcacacgcgctgggcagccacaaccgac
agtcatcactga
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