Klebsiella pneumoniae subsp. pneumoniae KPR0928: KPR0928_19855
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Entry
KPR0928_19855 CDS
T03371
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpq
Klebsiella pneumoniae subsp. pneumoniae KPR0928
Pathway
kpq00290
Valine, leucine and isoleucine biosynthesis
kpq00620
Pyruvate metabolism
kpq01100
Metabolic pathways
kpq01110
Biosynthesis of secondary metabolites
kpq01210
2-Oxocarboxylic acid metabolism
kpq01230
Biosynthesis of amino acids
Module
kpq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPR0928_19855
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPR0928_19855
Enzymes [BR:
kpq01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPR0928_19855
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AIE29836
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Position
4093823..4095499
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AA seq
558 aa
AA seq
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MLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSARKLQFWDL
LLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILRTFEALRGA
RRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQCEQQPETRWQYEYSPETFC
FTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHFSRRSEVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGIDPELR
FEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGDPWQMPYL
PIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQATDSDGKE
MTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQGQGNGLL
SAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGIDNDVARAS
LQALCNALSAADQAGGRK
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgctgagccatcctgctgaaaagtaccgtccctatccgccgatcgccctgcctgaccgc
cgctggccagaccggcaaatcagtcacgccccgcgctggctctcgactgacctgcgcgac
ggcaaccaggcgctggcggagcccatggacagcgcccgcaaactgcagttctgggatctg
ctgctggagtgcggctttaaagagattgaagtcgccttcccttccgcctcacaaaccgat
ttcaactttgtccgccagctgattgacgaacagcgcatcccggaggatgtcaccatccag
gtgctgacccaggcgcgagacccgctgatcctgcgcacctttgaggcgctgcgcggcgcc
cgccgggctaccgtccacctctacaatgccaccgcgccgctgttccgcgagctggttttc
ggcatggacaaggccgaggtgatcgccctcgcgacccgcgccacccggcttatccgtcag
cagtgcgaacagcagccggagacccgctggcaatatgaatattcgcctgaaaccttctgc
ttcaccgagcccgagtttgcgcttgagatttgcgaagcggtggcggatgtctggcagccc
tgcgccgagcgaccgatgatcgtcaatctgccggcgacggtggaagtcaacacccccaac
gtctatgccgatcagatcgagtatttttgccgccacttctcccgccgcagcgaggtctgc
atcagcgtgcacccgcataacgatcgcggcaccggcgtcgccagcgccgagctggcggtg
atggccggcgccgatcgggtagaaggctgcctgtttggcaacggcgaacgcaccggcaac
gtctgtctggtgactttggcgatgaacctctacagccagggcatcgaccctgagcttcgc
ttcgagcagatgaaccgggtggtggaggtggtggaaaactgcaaccagatccccgttcac
ccgcgccacccgtgggcgggaagtctggcttacaccgccttctccggctcccatcaggat
gcgatcaaaaaagggtttgatgcccgtcagcctggcgatccgtggcagatgccctacctg
cccattgacccgcaggatataggctgcagctatgaggcggtgatccgcgtcaacagccag
tcggggaagagcggcagcgcctggcttatcgaacaaaatcatggtctgaaactgccccgc
gggctgcagcaggacttcagccagcacgttcagcaggccaccgatagcgacggcaaagag
atgacccaccatgcgctgtggcagctgttccgcacgcgctacgggctgcaggcgcagccg
gcgctgacgctgctcgattatcagagcgccagccagcaggatggccagctttccctgcag
gcaacgctgcgtcaccacggcgaaacccgacgcctgcagggccagggcaacggcctgctc
tccgccgcagccagcgggctcagcgcgctgtttcggcagccgtttatgatcaaggactat
catgagcatacgctcggcgcgcgcagcgacagccggtcggtggcctatatccgctgcgtt
tttccgcaaggagaaagctactggggcgtgggtatcgataatgacgtggcgcgcgcctcg
ctgcaggcgctgtgcaatgcgctcagcgccgccgatcaggccgggggacgaaaatag
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