Klebsiella pneumoniae subsp. rhinoscleromatis SB3432: KPR_1003
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Entry
KPR_1003 CDS
T02793
Symbol
leuA
Name
(GenBank) highly similar to 2-isopropylmalate synthase from Klebsiella pneumoniae subsp. pneumoniae strain ATCC 700721 - MGH 78578 (sp|A6T4L9)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpr
Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
Pathway
kpr00290
Valine, leucine and isoleucine biosynthesis
kpr00620
Pyruvate metabolism
kpr01100
Metabolic pathways
kpr01110
Biosynthesis of secondary metabolites
kpr01210
2-Oxocarboxylic acid metabolism
kpr01230
Biosynthesis of amino acids
Module
kpr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPR_1003 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPR_1003 (leuA)
Enzymes [BR:
kpr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPR_1003 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
CCI75233
UniProt:
R4Y5S4
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Position
complement(1052440..1054011)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEY
ANIISGLYDRVPNIDKAIISVHTHDDLGIAVGNALAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYQESDYNLDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFNVQSGSSDIATASIKLVCGDEIKT
EAANGNGPVDAIYQAINRVTDYNIELVKYGLSAKGHGKDALGQVDIVVDYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgatacgaccttacgtgatggcgaacaagcgttacag
gcaagcctgagtgtcaaagagaagctgcagatcgcactggcccttgagcgaatgggggtc
gacgtaatggaagtcggtttcccggtatcctcgccgggcgattttgaatcggtgcaaacc
atcgcgcgcaccattaaaaacagccgcgtgtgcgccctggcgcgctgcgttgagaaagat
atcgacgtggcggcggaatcgttaaaagtggccgaggctttccgtattcatacctttatt
gccacctcgccgatgcatatcgccaccaaactgcgcagtacgctggatgaggttattgag
cgcgcgatctatatggtgaagcgggcacgcaactacactgacgacgttgagttctcctgt
gaagacgccggccgtacgccgattgccgatctggctcgcgtcgtggaagcggcgatcaac
gccggcgccaccaccattaatatcccggataccgtcggctataccatgccgttcgaatat
gccaacatcatcagcggcctgtatgatcgcgtgccgaatatcgacaaagcaattatttcc
gtccacacccatgatgatctgggcatcgctgtcggtaacgccctcgccgcggtccacgcc
ggtgcgcgccaggtagaaggtgcgatgaacggtatcggcgaacgcgccggcaactgcgcg
ctggaagaagtgatcatggcgatcaaagtgcgcaaagacatcatgaacgtgcacaccaac
attaatcatcatgaaatctggcgcaccagccagaccgtcagccagatctgcaatatgccg
atcccggcgaataaggccatcgtcggcaccggcgccttcgcccactcctccggcattcac
caggacggcgtgctgaagaaccgcgaaaactacgagatcatgaccccggaatctatcggc
ctgaaccaggtgcaactgaacctgacttcccgctccggccgcgcggcggtgaaacaccgg
atggaagagatgggctaccaggagagcgattacaacctggatcatctgtacgacgcattc
ctgaagctggcggacaaaaaaggccaggttttcgattacgatctggaagcgctggccttt
atcaacaagcagcaggaagagccagagcatttccgcctggattacttcaacgtccaatcc
ggatccagcgatatcgccaccgcctcgatcaaactggtctgcggggatgagatcaaaacc
gaagccgccaacggcaacggtccggtcgatgctatctaccaggcgattaaccgcgtcacc
gactacaacattgaattagtgaagtatggcttaagcgcgaaaggccacggcaaagacgcc
ctgggccaggtggatatcgtcgttgactacaatggccgccgcttccatggcgttggtctg
gcaacggatatcgtagagtcgtcagccaaagcgatggttcacgtgctgaacaacatctgg
cgcgccgccgaagtcgaaaaagaattgcaacgcaaagctcagaataaagagaacaataag
gaaaccgtgtaa
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