Klebsiella pneumoniae subsp. rhinoscleromatis SB3432: KPR_1272
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Entry
KPR_1272 CDS
T02793
Symbol
leuA
Name
(GenBank) similar to 2-isopropylmalate synthase from Pseudomonas stutzeri (sp|A4VNV6)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpr
Klebsiella pneumoniae subsp. rhinoscleromatis SB3432
Pathway
kpr00290
Valine, leucine and isoleucine biosynthesis
kpr00620
Pyruvate metabolism
kpr01100
Metabolic pathways
kpr01110
Biosynthesis of secondary metabolites
kpr01210
2-Oxocarboxylic acid metabolism
kpr01230
Biosynthesis of amino acids
Module
kpr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPR_1272 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPR_1272 (leuA)
Enzymes [BR:
kpr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPR_1272 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
CCI75502
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Position
complement(1332939..1334636)
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AA seq
565 aa
AA seq
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MTIKENTMLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSAR
KLQFWDLLLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILST
FEALRGARRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQCEQQPETRWQYE
YSPETFCFTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHF
SRRGEVCISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQ
GIDPELRFEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGD
PWQMPYLPIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQA
TDSDGKEMTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQ
GQGNGLLSAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGID
NDVARASLQALCNALSAADQAGGRK
NT seq
1698 nt
NT seq
+upstream
nt +downstream
nt
ctgaccattaaggagaacactatgctgagccatcctgctgaaaagtaccgtccctatccg
ccgatcgccctgcctgaccgccgctggccagaccggcaaatcagtcacgccccgcgctgg
ctgtcgactgacctgcgcgacggcaaccaggcgctggcggagcccatggacagcgcccgc
aaactgcagttctgggatctgctgctggagtgcggctttaaagagattgaagtcgccttc
ccttccgcctcacaaaccgatttcaactttgtccgccagctgattgacgaacagcgcatc
ccggaggatgtcaccatccaggtgctgacccaggcgcgagacccgctgatcctgagcacc
tttgaggcgctgcgcggcgcccgccgggctaccgtccacctctacaatgccaccgcgccg
ctgttccgcgagctggttttcggcatggacaaggccgaggtgatcgccctcgcgacccgc
gccacccggcttatccgtcagcagtgcgaacagcagccggagacccgctggcaatatgaa
tattcgcctgaaaccttctgcttcaccgagcccgagtttgcgcttgagatttgcgaagcg
gtggcggatgtctggcagccctgcgccgagcgaccgatgatcgtcaatctgccggcgacg
gtggaagtcaacacccccaacgtctatgccgatcagatcgagtatttttgccgccacttc
tcccgccgcggcgaggtctgcatcagcgtgcacccgcataacgatcgcggcaccggcgtc
gccagcgccgagctggcggtgatggccggcgccgatcgggtagaaggctgcctgtttggc
aacggcgaacgcaccggcaacgtctgtctggtgactttggcgatgaacctctacagccag
ggcatcgaccctgagcttcgcttcgagcagatgaaccgggtggtggaggtggtggaaaac
tgcaaccagatccccgttcacccgcgccacccgtgggcgggaagtctggcttacaccgcc
ttctccggctcccatcaggatgcgatcaaaaaagggtttgatgcccgtcagcctggcgat
ccgtggcagatgccctacctgcccattgacccgcaggatataggctgcagctatgaggcg
gtgatccgcgtcaacagccagtcggggaagagcggcagcgcctggcttatcgaacaaaat
catggtctgaaactgccccgcgggctgcagcaggacttcagccagcacgttcagcaggcc
accgatagcgacggcaaagagatgacccatcatgcgctgtggcagctgttccgcacgcgc
tacgggctgcaggcgcagccggcgctgacgctgctcgattatcagagcgccagccagcag
gatggccagctttccctgcaggcaacgctgcgtcaccacggcgaaacccgacgcctgcag
ggccagggcaacggcctgctctccgccgcagccagcgggctcagcgcgctgtttcggcag
ccgtttatgatcaaggactatcatgagcataccctcggcgcgcgcagcgacagccggtcg
gtggcctatatccgctgcgtttttccgcaaggagaaagctactggggcgtgggtatcgat
aatgacgtggcgcgcgcctcgctgcaggcgctgtgcaatgcgctcagcgccgccgatcag
gccgggggacgaaaatag
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