Kosakonia pseudosacchari: IP581_03400
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Entry
IP581_03400 CDS
T06897
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
kpse
Kosakonia pseudosacchari
Pathway
kpse00260
Glycine, serine and threonine metabolism
kpse00261
Monobactam biosynthesis
kpse00270
Cysteine and methionine metabolism
kpse00300
Lysine biosynthesis
kpse01100
Metabolic pathways
kpse01110
Biosynthesis of secondary metabolites
kpse01120
Microbial metabolism in diverse environments
kpse01230
Biosynthesis of amino acids
Module
kpse_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kpse_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
kpse_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
kpse00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
IP581_03400 (thrA)
00270 Cysteine and methionine metabolism
IP581_03400 (thrA)
00300 Lysine biosynthesis
IP581_03400 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
IP581_03400 (thrA)
Enzymes [BR:
kpse01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
IP581_03400 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
IP581_03400 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
QOV64726
LinkDB
All DBs
Position
726534..728996
Genome browser
AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
IPNISDAERIFADLLQGLADAQAGFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSINA
ALICRGEKLSIAIMAGLLEARGHKVSVIDPVEKLLAVGHYLESTVDIAESTRRIAASRIP
ADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQFQIPCLIKNTGNPQAPGTLIGATSD
EDGLPVKGISNLNNMAMFSVSGPGMKGMVGMAARVFAAMSRNGISVVLITQSSSEYSISF
CVPQSDCSRAQRAMSEEFYLELKEGLLEPLAVMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQLKRQQTWLKNKHIDLRVCGVANSKALLTNVHGLNLDNWQAELSEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRRAAEKSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELQHFSGILSGSLSFIFGKLDEGVSLSAATNLA
REMGYTEPDPRDDLSGMDVARKLLILARETGRELELSDIIIEPVLPASFDDSGDVESFMA
RLPELDDDFAARVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcagagcgttttctgcgtgtt
gccgatatcctggaaagtaatgccaggcaggggcaggtagccaccgtgctttctgcccct
gcgaaaattactaaccatctggtggcaatgatcgaaaaaacgatcggcggccaggatgcc
attccgaacattagtgacgccgagcgtatcttcgccgacctgctgcaagggctggcggat
gcgcaagctgggtttcctctcgcacaattaaaagcgtttgttgaacaagagttcgcgcag
atcaaacacgtcctgcatggtatcagcctgctcggccagtgcccggacagtatcaacgct
gcgttaatttgccgtggtgagaaactctctatcgccatcatggcagggttactggaagcg
cgtggtcacaaagttagcgttatcgatccggttgagaaattgctcgctgtcggccattac
cttgaatcaacggtcgatatcgctgaatctactcgccgtatcgccgccagccgcattcct
gcggatcatatggtgctgatggccggtttcaccgccggaaacgagaagggcgagctggtg
gtacttgggcgtaatggttccgactactctgctgccgtgctcgcggcctgcctgcgcgca
gattgttgtgaaatctggaccgatgtcgacggcgtttatacctgcgacccgcgccaggtg
cctgacgccaggctgctcaaatcgatgtcgtaccaggaagccatggagctctcctacttc
ggcgccaaagttcttcaccctcgcaccattacccccatcgctcagtttcaaattccttgc
ctgattaaaaacaccggaaacccgcaagcaccgggtacgctgattggcgcgacctctgat
gaagatggtctgccggtaaaaggcatttcgaatctgaataacatggcgatgttcagcgtc
tccggaccggggatgaaaggtatggttggcatggcggcacgcgttttcgccgcgatgtcg
cgcaacggcatttccgtcgtgttgatcactcaatcctcctcggagtacagcatcagcttc
tgtgtgccgcaatccgattgctcccgtgcccagcgcgccatgagcgaagagttctatctc
gaattgaaagaagggctgctggagccgctggcggtgatggagcgtctggcgatcatctct
gtcgtcggtgacggtatgcgcacattgcgcggaatttcggcgaagttctttgcggcgctg
gcgcgcgcgaatattaatattgtggcgattgctcagggctcctctgaacgctcgatctct
gtggtggttagcaacgacgatgccaccaccggcgtgcgcgtcacgcaccagatgctgttt
aacaccgaccaggtgatcgaagtctttgtgattggcgttggcggcgtcggcggcgcgctg
ctggaacagcttaagcgccagcaaacgtggctgaaaaacaaacatattgacctgcgcgtt
tgtggtgtggcgaactcgaaagcgctgttgactaacgttcatggcctgaacctggataac
tggcaagcggaacttagcgaagccaaagagccgtttaacctgggccgcctgattcgcctg
gtgaaagagtatcacctgctgaacccggtgattgttgactgtacttccagccaggcggtg
gccgaccagtatgcggatttcctgcgggaaggtttccacgttgtcacgccgaacaaaaaa
gccaacacctcatcgctggattattaccaccagttgcgtcgcgcagcggaaaagtcgcgg
cgtaaattcctgtacgacacgaacgttggcgcgggcttgccggtgattgaaaacctgcaa
aacctgctaaatgcgggtgacgagttgcagcatttctccggcattctttccggttccttg
tcgtttattttcggcaagctggatgaaggggtgagcctgtcggcagcaacgaatctcgcc
cgcgaaatgggctacaccgaaccggatccgcgagatgatctctccggtatggatgtggcg
cgtaagctgctgattctggcgcgcgaaaccggtcgtgaactggagttgtcggatatcatc
atcgaaccggtgttgccggcgagttttgacgattcaggcgatgtcgagagttttatggcg
cgtttgccggagctggatgatgattttgccgcgcgagtcgcaaaagcgcgcgatgaaggt
aaggtgctgcgttacgttggcaacattgaagaagatggcacttgccgggtgaaaatcgcg
gcggtcgatggcaacgatccgctgttcaaagtgaaaaacggcgagaacgcgctggcgttc
tacagccactattaccagccgctaccgctggtgctgcgcgggtatggcgcgggtaacgat
gtgacggcagcgggcgtgttcgccgacttgctgcgcaccctgtcctggaagttaggagtc
tga
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