Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1: VK055_2482
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Entry
VK055_2482 CDS
T03418
Name
(GenBank) UDP-MurNAc-L-Ala-D-Glu-L-Lys:D-Ala-D-Ala ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kpt
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Pathway
kpt00300
Lysine biosynthesis
kpt00550
Peptidoglycan biosynthesis
kpt01100
Metabolic pathways
kpt01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kpt00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
VK055_2482
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
VK055_2482
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
VK055_2482
Enzymes [BR:
kpt01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
VK055_2482
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
YAcAr
LpxD
Motif
Other DBs
NCBI-ProteinID:
AIK81079
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All DBs
Position
complement(2520241..2521599)
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AA seq
452 aa
AA seq
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MIRFTLSQLAAIAHGERQGSDVAIDEVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKAA
GAGALLVSRPLACDLPQVIVNDTRQAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAILNADNNDWLNWQAVIGDRKVWRFS
PNAANSDFTATNVQITSHGTEFTLQTPTGNVDVLLPLPGRHNIANALAATSLAMAVGADL
AAVKAGLAQLQAVPGRLFPIRLTESQLLLDDSYNANVGSMTAAVQVLSEMPGFRTLVVGD
MAELGAESAACHREVGEAAKAAGLDCVLSVGALSADISRASGVGEHFNDKAAVVARLREL
LAEHKIMTILVKGSRSAAMEEVVRALQETGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgctttacgttaagtcaacttgccgcgatcgcccatggcgaacggcagggtagc
gatgtcgctatcgacgaggtgaccaccgatacccgtaaagtgacggcgggctgcctgttt
gtggcgctgaaaggggagcgtttcgacgcccatgattttgccgaacaggcgaaagcggcg
ggcgccggcgcgctgctggtgagtcgtccgctggcctgcgatctcccgcaggtgattgtg
aacgatacccggcaggctttcggtgagttagccgcctgggtgcgtcagcaggtgccgact
cgcgtcgtcgccctgaccggctcgtccggtaaaacctcggttaaagagatgaccgcggcg
atcctcagccagtgcggcaacacgctgtataccgccggcaacctgaacaacgatatcggc
gtcccgatgacgctgctgcggctgaccaaagagcatcagtacgcggtgatcgaactcggc
gccaaccaccagggcgaaatcgcctggaccgtcagcctgacgcgtccggaagcggcgctg
gtcaacaaccttgctgcggcgcacctggaaggtttcggttcgctggcgggcgtggcgaag
gcgaagggcgaaatctataccggtctgccggaaaatggcatcgccatcctcaatgccgac
aataacgactggctgaactggcaggcggtgattggcgatcgcaaagtgtggcgcttctcg
ccgaacgcggcgaacagcgatttcacggcgaccaacgtgcagatcaccagccacggcacc
gaatttacgctgcagaccccaaccggcaacgttgacgtactgctgccgctgccgggacgc
cacaacatcgctaatgcgctggccgccacttcgctggcgatggcggtaggcgccgatttg
gcggcggtgaaagccggactggcgcagctgcaggccgttccgggacgtctgttcccgatc
cggctgaccgagagccagctgctgctggatgattcctataacgctaacgttggttcgatg
accgcggcggtgcaggtgctgtcagagatgcccggctttcgcacgctggtggtcggcgat
atggcagagcttggcgcggagagcgcggcctgccatcgcgaagtcggcgaagcggcgaaa
gcggcgggtctggattgcgtcctcagcgtcggcgccttgagcgcggatatcagccgcgcc
agcggcgtgggcgaacattttaacgataaagccgccgtggtggctcgcctgcgcgagctg
ctggcggagcacaaaataatgaccattttagtgaagggttcacgtagtgccgccatggaa
gaggtagtacgcgcattacaggagactgggacatgttag
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