Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1: VK055_2572
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Entry
VK055_2572 CDS
T03418
Symbol
thrA
Name
(GenBank) thrA
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
kpt
Klebsiella pneumoniae subsp. pneumoniae ATCC 43816 KPPR1
Pathway
kpt00260
Glycine, serine and threonine metabolism
kpt00261
Monobactam biosynthesis
kpt00270
Cysteine and methionine metabolism
kpt00300
Lysine biosynthesis
kpt01100
Metabolic pathways
kpt01110
Biosynthesis of secondary metabolites
kpt01120
Microbial metabolism in diverse environments
kpt01230
Biosynthesis of amino acids
Module
kpt_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kpt_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
kpt_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
kpt00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
VK055_2572 (thrA)
00270 Cysteine and methionine metabolism
VK055_2572 (thrA)
00300 Lysine biosynthesis
VK055_2572 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
VK055_2572 (thrA)
Enzymes [BR:
kpt01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
VK055_2572 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
VK055_2572 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AIK81169
UniProt:
A0A1Y0Q3S0
LinkDB
All DBs
Position
complement(2625226..2627688)
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNIADAERIFAELLQGLADAQPAFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSVNA
ALICRGEKLSIAIMAGLLEARGHKVSVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRAMEDEFYLELKEGLLEPLAIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQIKRQQGWLKNKHIDLRVCGVANSQALLTSVHGLNLENWSAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELRHFSGILSGSLSFIFGKLDEGVSFSAATAMA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELADIIVESALPPDFDASGDVETFMA
RLPSLDDGFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcggaacggtttctgcgggtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgacggtcctgtctgccccg
gcgaagatcactaaccacctggtagcgatgattgaaaagaccattggcggccaggatgcc
ctccccaatattgccgacgccgaacgcatttttgccgaacttcttcagggccttgccgac
gcccagcccgctttcccgcttgcccagttaaaagccttcgtggagcaggaatttgctcag
attaagcatgttctgcacggcatcagcctgctgggtcagtgcccggacagcgtcaatgcc
gcgctgatctgccgcggcgaaaagctctccatcgccatcatggcgggtctgctggaagcc
cgtggacataaagtcagtgtcattaacccggtcgaaaaactgctcgccgtgggccactat
ctggaatccaccgtcgatatcgccgaatccacccgccgcattgccgccagccagatcccg
gcagaccatatgatcctgatggccgggtttaccgccggcaatgagaaaggcgagctggtg
gtgctggggcgtaacggctccgactactcggctgcggtactggccgcctgcctgcgcgct
gactgctgcgaaatctggaccgatgtcgacggagtgtacacctgcgatccgcgtcaggtg
ccggatgcgcgcctgctgaaatcgatgtcttatcaggaggcgatggagctctcctacttt
ggcgcgaaagtgctgcacccgcgcaccattgcccctatcgcccagttccaaatcccatgc
ctgattaaaaataccggcaacccgcaggcgccgggaacgcttatcggcgccagccgcgac
gaggacgatttgccggtgaaaggcatctctaacctcaacaacatggcgatgttcaacgtc
tccgggccggggatgaaagggatggtcggcatggcggcccgcgtcttcgccaccatgtcc
cgcgccggcatctcggtggtgttgatcactcaatcttcttcggagtacagcatcagtttc
tgcgtgccgcagagcgactgcgcacgtgccaaacgggcgatggaagatgagttttatctg
gagctgaaagaggggctgctggagccgctggcgattatggagcgtctggcgatcatctcc
gtggtgggcgacggaatgcgtaccctgcgcggtatctcggcgaaattctttgcggcactg
gcccgcgccaatatcaatatcgtggcgattgcccagggctcttccgagcgctcaatttcg
gtagtggtcagcaatgacgacgccaccaccggcgtgcgcgtgacccatcagatgctgttc
aacaccgaccaggtgattgaagtgtttgtcatcggcgtcggcggcgtcggcggcgcgctg
ctagagcagatcaagcgccagcaggggtggctgaagaacaaacatatcgatctgcgcgtc
tgcggtgtagccaattctcaggcgctgctgaccagcgtgcatggcctgaatctggaaaac
tggagtgcggaactggcggaggcgaaagagccgtttaatcttggccgcctgatccgcctg
gtgaaagagtaccacctgctcaatccggtgatcgtcgactgtacctccagccaggcggtc
gccgatcagtatgccgacttcctgcgcgaaggtttccatgtggtgacgccgaacaaaaag
gccaatacctcttcgctggattactatcaccagctgcgccatgcggccagcagctcgcgg
cgtaagttcctctatgacactaacgttggcgcgggcctgccggtgattgagaacctgcag
aacctgctcaacgccggcgatgagctgcgccatttctccgggatcctgtccggctccctg
tcgtttatcttcggcaagctggacgagggggtgagtttctccgcggcgacggcgatggcc
cgtgagatggggtataccgagccggatccgcgcgacgatttatccggggtggatgtggcg
cgtaaactgctgattctggcccgtgagaccgggcgtgaactggagctggcggacattatc
gtcgagtcggcgctgccgccggacttcgacgccagcggcgatgtcgagacctttatggcc
cgcctgccgtcgctggacgatggttttgcctcgcgggttgctaaggcgcgcgatgaaggt
aaagtcttgcgctacgtcggtaacatcgaagaggatggtacctgccgggtaaaaatagcc
gcggttgacggcaacgatccgctgttcaaagttaagaatggtgagaacgcgctggctttt
tatagccattattatcagccattgccgctggtgctgcgcggctatggcgccgggaacgac
gtcacggcggccggcgtattcgccgacctgctgcgcaccctgtcctggaagttaggagtt
taa
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