Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_4136
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Entry
KP1_4136 CDS
T00910
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
kpu
Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)
Pathway
kpu00230
Purine metabolism
kpu01100
Metabolic pathways
kpu01110
Biosynthesis of secondary metabolites
Module
kpu_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
kpu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
KP1_4136 (purL)
Enzymes [BR:
kpu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
KP1_4136 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
BAH64677
LinkDB
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Position
complement(3968278..3972165)
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AA seq
1295 aa
AA seq
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MMEILRGSPALSAFRINKLLARFQAANLPVSAIYAEYIHFADLNAPLSADDRERLARLLQ
YGPSLSSHTPTGKLLLVTPRPGTISPWSSKATDIAHNCGLAQVVRLERGVAYYVEASTLT
EAQWATVAAELHDRMMESVFDELEAGEKLFAHHQPTPVTSVDLLGEGRQALIDANLRLGL
ALADDEIDYLQDAFTRLGRNPNDIELYMFAQANSEHCRHKIFNADWIIDGEQQPKSLFKM
IKNTFEKTPDYVLSAYKDNAAVMEGSEVGRYFADHQTGRYDFHQEPAHILMKVETHNHPT
AISPWPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLRIPGFEQPWEEDFGKPDRIV
TALDIMTEGPLGGAAFNNEFGRPALNGYFRTYEEKVTSHNGEELRGYHKPIMLAGGIGNI
RGEHVQKGEITVGAKLIVLGGPAMNIGLGGGAASSMASGQSDADLDFASVQRDNPEMERR
CQEVIDRCWQLGDANPILFIHDVGAGGLSNAMPELVSDGGRGGKFQLRDILSDEPGMSPL
EIWCNESQERYVLAVAPEQLPLFDELCRRERAPYAVIGEATAEQHLSLSDSHFNDQPIDL
PLDVLLGKTPKMTRDVQTLKAQGSALDRQPITLADAVNRVLHLPTVAEKTFLVTIGDRTV
TGMVARDQMVGPWQIPVANCAVTTASLDSYYGEAMAMGERAPVALLDFAASGRLAVGEAL
TNIAATQIGELNRVKLSANWMAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMS
MKTRWQEGSEQREMTSPLSLVISAFARVEDVRHTVTPQLSTEDNALLLIDLGKGHNALGA
TALAQVYRQLGDKPADVRDVAQLKGFWNAMQALVAQRKLLAYHDRSDGGLLVTLAEMAFT
GHCGVEADIAALGDDHLAALFNEELGAVIQVRAADREAVEAILAVNGLADCVHYLGKAVE
GDRFVLTAGGQTVFSESRTTLRMWWAETTWQMQRLRDNPACADQEHQAKANDADPGLNVK
LSFDINDDVAAPYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRT
GLGDFHALVACGGFSYGDVLGAGEGWAKSILFNERVRDEFATFFHRPQTLALGVCNGCQM
MSNLRELIPGSDLWPRFVRNQSDRFEARFSLVEVTQSPSLLLEGMVGSRMPIAVSHGEGQ
VEVRDSAHLAQLESKGLVALRFVDNFGKVTETYPANPNGSPNGITAVTSESGRATIMMPH
PERVFRTVSNSWHPENWGEDSPWMRIFRNARKQLG
NT seq
3888 nt
NT seq
+upstream
nt +downstream
nt
atgatggaaattttgcgtggttcacctgcactgtcggcattccgtattaataaactgctg
gcacgatttcaggcggccaaccttccggtaagcgccatatatgccgaatatattcatttt
gccgatctgaatgccccgctgagcgctgacgatcgcgagcgcctggcgcgattgcttcag
tatggcccgagcttgagcagccataccccgaccggtaaattactgctcgtgacccctcgc
cctggcaccatctctccctggtcttctaaagctaccgatatcgctcacaactgcggtctg
gcgcaggttgtgcgtcttgagcgcggcgtggcgtattacgttgaagcctcaaccctgacc
gaagcgcagtgggccacggtggcggcggagctgcacgaccgcatgatggagagcgtcttc
gacgagctggaagcgggcgagaagctgttcgctcaccatcagccgacgccggtcaccagc
gtcgacctgctgggcgaagggcgtcaggcgctgattgacgccaacctccgtctgggtctg
gcgctggccgacgacgaaattgactacctgcaggacgcgtttacccgcctgggacgcaac
ccgaacgatatcgagctgtatatgttcgcccaggcgaactcagagcactgtcgccacaag
attttcaacgccgactggatcatcgacggcgaacagcagccgaagtcgctgttcaaaatg
atcaaaaacacctttgaaaaaacgccagactacgtgctgtcggcttataaagataatgcc
gcggtgatggaagggtctgaagtcgggcgctatttcgccgaccatcagaccggacgctac
gacttccatcaggagccggcgcacattctgatgaaggtggaaacccataaccacccgacg
gccatctctccatggccgggcgcggcaactggctccggcggcgaaatccgcgatgaaggc
gccaccggccgcggcgcgaagccgaaagcgggcctggtgggcttctcggtttccaacctg
cgtatcccgggcttcgaacagccgtgggaagaagatttcggtaaaccggatcgcattgtc
accgccctggacatcatgaccgaaggcccgctgggcggcgcggcgtttaacaacgaattt
ggtcgtccggcgctgaacggctacttccgcacctatgaagagaaagtcaccagccacaat
ggcgaagagctgcgtggctaccacaaaccgatcatgctggccggcggtatcggcaacatc
cgcggtgagcacgtgcagaagggcgagattaccgtcggcgcgaagctgatcgtgctgggc
ggcccggcgatgaacatcggcctcggcggcggcgcggcgtcttctatggcctccggccag
tccgatgccgatctcgatttcgcctccgtacagcgtgacaacccggaaatggagcgccgc
tgtcaggaagtgatcgaccgctgctggcagttgggcgacgccaacccgatcctctttatc
cacgacgttggcgccggcggtctctccaacgctatgccggagctggtgagcgacggcggc
cgcggcggtaaattccagctgcgcgatattctcagcgatgagccagggatgagtccgctg
gagatctggtgtaacgaatcgcaggaacgttatgttctggcggtcgccccggagcagctg
ccgctgttcgacgaactgtgccgccgcgagcgcgcgccttatgccgttatcggcgaagcc
accgctgagcagcatctgagcctgagcgacagccactttaacgatcagccgatcgacctg
ccgctggacgtcctgctcggcaaaacgccgaaaatgacccgcgacgtgcagactctgaaa
gctcagggtagtgcactggatcgccaaccgattacccttgccgatgcggttaaccgcgtt
ctgcatctgccgacggtggccgagaaaaccttcctcgtcaccatcggcgaccgcaccgtg
accggtatggtcgcccgcgaccagatggttggcccgtggcagatcccggtggccaactgc
gcggtgaccaccgccagcctcgacagctactatggcgaagcgatggcgatgggcgagcgc
gccccggtcgccctgctggacttcgcggcctctggccgtctggcggtcggcgaagcgctg
accaacatcgccgccacgcagattggcgagctgaaccgcgtgaagctgtcggctaactgg
atggccgccgccggccacccgggtgaagacgctggcctgtatgaggcggtgaaagcggtg
ggcgaagagctgtgcccggcgctgggcctgaccattccggtcggtaaagactcgatgtcg
atgaaaacccgctggcaggaaggcagcgagcagcgcgagatgacctctccgctgtcgctg
gtcatctctgccttcgcccgtgtcgaagatgtccgtcataccgtcacgccgcagctttcg
acggaagataacgccctgctgctgatcgacctcggtaaagggcacaacgcgctgggcgcg
acggcgctggcgcaggtctatcgccagctcggcgacaagccggctgacgtgcgcgatgtc
gcgcaactgaaaggcttctggaatgcgatgcaggccctggtggcgcagcgtaaactgctg
gcctaccacgaccgctccgacggcggtctgcttgtcacgctggcggaaatggcctttacc
ggccactgcggcgtggaagcggatatcgccgcgctgggcgacgaccatctggccgcgctg
ttcaacgaagagctgggggcggtgattcaggtccgcgccgcagaccgtgaggcggtggaa
gccattctggcggttaacggcctggcggactgcgtgcattacctcggtaaagcggttgag
ggcgatcgcttcgtgctgaccgccggcggtcagacggtgttcagcgaaagccgcaccacg
ctgcgcatgtggtgggcggaaaccacctggcagatgcagcgtctgcgcgacaacccggcc
tgcgccgatcaggagcatcaggcgaaagccaatgatgccgacccgggcctcaatgtgaag
ctctcgtttgatattaacgacgacgtcgccgccccgtacattgccaccggcgcgcggccg
aaagtggccgtcctgcgcgagcagggggtgaactcccacgttgaaatggcggccgccttc
catcgtgccggctttgacgccatcgacgtgcatatgagcgacctgctggccggccggacc
ggtctgggcgatttccatgccctggtagcctgcggcggcttctcctacggcgacgtgttg
ggcgcgggcgagggctgggcgaagtcgattctgttcaacgagcgcgtgcgcgatgagttc
gcgaccttcttccaccgtccgcagacgctggcgctcggcgtgtgcaacggctgtcagatg
atgtccaacctgcgcgagctgatcccgggcagcgacctgtggccgcgctttgtgcgcaac
cagtctgaccgctttgaagcgcgctttagcctggtggaagtgacgcaaagcccatccctg
ctgctggaaggcatggttggctcacggatgccgattgcggtctcccacggcgaaggtcag
gtggaagtgcgcgacagcgcgcatctggcccagctggagagcaaaggtctggtggcgctg
cgcttcgtggataacttcggcaaagtgaccgaaacctatccggcgaacccgaacggttcc
ccgaacggtatcaccgcggtgaccagcgaaagcgggcgcgcgaccatcatgatgccgcac
ccggaacgcgtcttccgcaccgtaagcaactcctggcacccggagaactggggcgaggat
agcccgtggatgcgtatcttccgtaacgcgcgtaaacagctgggttaa
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