Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1): KP1_4281
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Entry
KP1_4281 CDS
T00910
Name
(GenBank) putative isopropylmalate/homocitrate/citramalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpu
Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044 (serotype K1)
Pathway
kpu00290
Valine, leucine and isoleucine biosynthesis
kpu00620
Pyruvate metabolism
kpu01100
Metabolic pathways
kpu01110
Biosynthesis of secondary metabolites
kpu01210
2-Oxocarboxylic acid metabolism
kpu01230
Biosynthesis of amino acids
Module
kpu_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KP1_4281
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KP1_4281
Enzymes [BR:
kpu01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KP1_4281
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAH64809
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All DBs
Position
4110972..4112648
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AA seq
558 aa
AA seq
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MLSHPAEKYRPYPPIALPDRRWPDRQISHAPRWLSTDLRDGNQALAEPMDSARKLQFWDL
LLECGFKEIEVAFPSASQTDFNFVRQLIDEQRIPEDVTIQVLTQARDPLILRTFEALRGA
RRATVHLYNATAPLFRELVFGMDKAEVIALATRATRLIRQQCEQQPETRWQYEYSPETFC
FTEPEFALEICEAVADVWQPCAERPMIVNLPATVEVNTPNVYADQIEYFCRHFSRRGEVC
ISVHPHNDRGTGVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLAMNLYSQGIDPELR
FEQMNRVVEVVENCNQIPVHPRHPWAGSLAYTAFSGSHQDAIKKGFDARQPGDPWQMPYL
PIDPQDIGCSYEAVIRVNSQSGKSGSAWLIEQNHGLKLPRGLQQDFSQHVQQATDSDGKE
MTHHALWQLFRTRYGLQAQPALTLLDYQSASQQDGQLSLQATLRHHGETRRLQGQGNGLL
SAAASGLSALFRQPFMIKDYHEHTLGARSDSRSVAYIRCVFPQGESYWGVGIDNDVARAS
LQALCNALSAADQAGGRK
NT seq
1677 nt
NT seq
+upstream
nt +downstream
nt
atgctgagccatcctgctgaaaagtaccgtccctatccgccgatcgccctgcctgaccgc
cgctggccagaccggcaaatcagccacgccccgcgctggctgtcgactgacctgcgcgac
ggcaaccaggcgctggcggagcccatggacagcgcccgcaaactgcagttctgggatctg
ctgctggagtgcggctttaaagagattgaagtcgccttcccttccgcctcacaaaccgat
ttcaactttgtccgccagctgattgacgaacagcgcatcccggaggatgtcaccatccag
gtgctgacccaggcgcgagacccgctgatcctgcgcacctttgaggcgctgcgcggcgcc
cgccgggctaccgtccacctatacaatgccaccgcgccgctgtttcgcgagctggttttc
ggcatggacaaggccgaggtgatcgccctcgcgacccgcgccacccggcttatccgtcag
cagtgcgaacagcagccggagacccgctggcaatatgaatattcgcctgaaaccttctgc
ttcaccgagcccgagtttgcgcttgagatttgcgaagcggtggcggatgtctggcagccc
tgcgccgagcgaccgatgatcgtcaatctgccggcgacggtggaagtcaacacccccaac
gtctatgccgatcagatcgagtatttttgccgccacttctcccgccgcggcgaggtctgc
atcagcgtgcacccgcataacgatcgcggcaccggcgtcgccagcgccgagctggcggtg
atggccggcgccgatcgggtagaaggctgcctgtttggcaacggcgaacgcaccggcaac
gtctgtctggtgactttggcgatgaacctctacagccagggcatcgaccctgagcttcgc
ttcgagcagatgaaccgggtggtggaggtggtggaaaactgcaaccagatccccgttcac
ccgcgccacccgtgggcgggaagtctggcttacaccgccttctccggctcccatcaggat
gcgatcaaaaaagggtttgatgcccgtcagcctggcgatccgtggcagatgccctacctg
cccattgacccgcaggatataggctgcagctatgaggcggtgatccgcgtcaacagccag
tcggggaagagcggcagcgcctggcttatcgaacaaaatcatggtctgaaactgccccgc
gggctgcagcaggacttcagccagcacgttcagcaggccaccgatagcgacggcaaagag
atgacccaccatgcgctgtggcagctgttccgcacgcgctacgggctgcaggcgcagccg
gcgctgacgctgctcgattatcagagcgccagccagcaggatggccagctttccctgcag
gcaacgctgcgtcaccacggcgaaacccgacgcctgcagggccagggcaacggcctgctc
tccgccgcagccagcgggctcagcgcgctgtttcggcagccgtttatgatcaaggactat
catgagcataccctcggcgcgcgcagcgacagccggtcggtggcctatatccgctgcgtt
tttccgcaaggagaaagctactggggcgtgggtatcgataatgacgtggcgcgcgcctcg
ctgcaggcgctgtgcaatgcgctcagcgccgccgatcaggccgggggacgaaaatag
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