Kitasatospora purpeofusca: ACFCLZ_11275
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Entry
ACFCLZ_11275 CDS
T11279
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kpur Kitasatospora purpeofusca
Pathway
kpur00300
Lysine biosynthesis
kpur00550
Peptidoglycan biosynthesis
kpur01100
Metabolic pathways
kpur01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kpur00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ACFCLZ_11275 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ACFCLZ_11275 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ACFCLZ_11275 (murF)
Enzymes [BR:
kpur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ACFCLZ_11275 (murF)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
XdhC_C
DUF2126
Motif
Other DBs
NCBI-ProteinID:
XHR66198
LinkDB
All DBs
Position
complement(2727187..2728587)
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AA seq
466 aa
AA seq
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MIALTLAEVAAAVGGTLAGADPDVLVTAPVEVDSRKVRPGGLFAAFVGERVDGHDYAATA
VEAGAVAVLASRPVGVPAVLVDSVVDALGKLARTVVGRSDAAVVALTGSAGKTSTKDLIA
QLLERLGDTVYPPGSLNNEIGHPMTALRVEDATRHLVLEMGARHKGDIEYLTSITPPRIG
LVLNVGTAHVGEFGSQEAIAEAKGELVEALPADGAAILNADDRLVRAMAARTKAKVVFFG
ESAEADVRAQDVRLDSTGRPSFTLSTPAGSAPVQLRLYGEHHVSNALAAAAVAMELGMTV
DDTAEALSQAGALSRWRMEVVDRADGVTVVNDAYNANPDSMRAALRALISMGGRGPERRR
TWAVLGEMRELGEDSLAEHDAIGRLAVRLDVTKLVAVGGREAACMELGARNEGSWGEESV
LVSDADAAVELLRSQLRPGDVVLVKASRSVGLEKVAEALLADGAAE
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgcactgaccctcgccgaggtggccgccgcagtcgggggaaccctggccggcgcc
gaccccgacgtcctggtgaccgccccggtcgaggtcgactcccgcaaggtccgccccggc
ggcctgttcgcggccttcgtcggcgagcgcgtggacggccacgactacgcggccaccgcg
gtcgaggccggcgccgtcgcggtgctggcctcccgcccggtcggcgtgcccgccgtgctg
gtcgacagcgtggtggacgccctcggcaagctggcccgcaccgtcgtgggccgctccgac
gccgccgtggtcgcgctgaccggctcggccggcaagaccagcaccaaggacctcatcgcc
cagctgctggagcgcctgggcgacaccgtctacccgcccggctcgctcaacaacgagatc
gggcacccgatgaccgccctgcgggtcgaggacgccacccggcacctggtgctggagatg
ggtgcccggcacaagggcgacatcgagtacctcacctcgatcaccccgccccggatcgga
ctggtgctcaacgtcggcaccgcgcacgtcggcgagttcggctcccaggaggcgatcgcc
gaggccaagggcgaactcgtcgaggccctgcccgccgacggcgcggcgatcctcaacgcg
gacgaccgcctggtgcgcgccatggccgcgcgcaccaaggccaaggtggtgttcttcggc
gagtccgcggaggccgacgtccgggcacaggacgttcgcctggactccaccggacgtcca
tccttcacgctgagcaccccggccggttccgcacccgtgcagctgcgcctgtacggtgag
caccacgtctcgaacgccctcgccgccgccgcggtggcgatggagctcgggatgaccgtc
gacgacaccgccgaagcgctgagccaggcgggtgcgctgtcccgctggcgcatggaggtc
gtcgaccgggccgatggtgtcaccgtcgtcaacgacgcctacaacgcgaaccccgactcg
atgcgggccgcgctgcgggcgctcatctcgatgggggggcgcggcccggagcgccgccgc
acctgggcggtgctcggcgagatgcgggagctcggcgaggacagcctggccgagcacgac
gccatcgggcggctcgccgtccggctggacgtcaccaagctggtggcggtcggcggacgc
gaggcggcctgcatggaactgggcgcgaggaacgaaggttcgtggggtgaggagtcggtg
ctggtgtccgacgcggacgcggcggtcgaactgctgcgcagtcagctgcggccgggggat
gtggtgctggtgaaggcctcccgttcggtggggctggagaaggtggccgaggccctcctc
gcggacggtgcggccgagtaa
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