Klebsiella pneumoniae subsp. pneumoniae KPNIH29: KPNIH29_03860
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Entry
KPNIH29_03860 CDS
T03465
Symbol
thrA
Name
(GenBank) aspartate kinase
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
kpv
Klebsiella pneumoniae subsp. pneumoniae KPNIH29
Pathway
kpv00260
Glycine, serine and threonine metabolism
kpv00261
Monobactam biosynthesis
kpv00270
Cysteine and methionine metabolism
kpv00300
Lysine biosynthesis
kpv01100
Metabolic pathways
kpv01110
Biosynthesis of secondary metabolites
kpv01120
Microbial metabolism in diverse environments
kpv01230
Biosynthesis of amino acids
Module
kpv_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
kpv_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
kpv_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
kpv00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
KPNIH29_03860 (thrA)
00270 Cysteine and methionine metabolism
KPNIH29_03860 (thrA)
00300 Lysine biosynthesis
KPNIH29_03860 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
KPNIH29_03860 (thrA)
Enzymes [BR:
kpv01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
KPNIH29_03860 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
KPNIH29_03860 (thrA)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
DUF6247
Motif
Other DBs
NCBI-ProteinID:
AIX67734
UniProt:
A0A1Y0Q3S0
LinkDB
All DBs
Position
794733..797195
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AA seq
820 aa
AA seq
DB search
MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKITNHLVAMIEKTIGGQDA
LPNIADAERIFAELLQGLADAQPAFPLAQLKAFVEQEFAQIKHVLHGISLLGQCPDSVNA
ALICRGEKLSIAIMAGLLEARGHKVSVINPVEKLLAVGHYLESTVDIAESTRRIAASQIP
ADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACLRADCCEIWTDVDGVYTCDPRQV
PDARLLKSMSYQEAMELSYFGAKVLHPRTIAPIAQFQIPCLIKNTGNPQAPGTLIGASRD
EDDLPVKGISNLNNMAMFNVSGPGMKGMVGMAARVFATMSRAGISVVLITQSSSEYSISF
CVPQSDCARAKRAMEDEFYLELKEGLLEPLAIMERLAIISVVGDGMRTLRGISAKFFAAL
ARANINIVAIAQGSSERSISVVVSNDDATTGVRVTHQMLFNTDQVIEVFVIGVGGVGGAL
LEQIKRQQGWLKNKHIDLRVCGVANSQALLTSVHGLNLENWSAELAEAKEPFNLGRLIRL
VKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVVTPNKKANTSSLDYYHQLRHAASSSR
RKFLYDTNVGAGLPVIENLQNLLNAGDELRHFSGILSGSLSFIFGKLDEGVSFSAATAMA
REMGYTEPDPRDDLSGVDVARKLLILARETGRELELADIIVESALPPDFDASGDVETFMA
RLPSLDDGFASRVAKARDEGKVLRYVGNIEEDGTCRVKIAAVDGNDPLFKVKNGENALAF
YSHYYQPLPLVLRGYGAGNDVTAAGVFADLLRTLSWKLGV
NT seq
2463 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagttcggcggtacatcagtggcaaatgcggaacggtttctgcgggtt
gccgatattctggagagtaatgccaggcaggggcaggtagcgacggtcctgtctgccccg
gcgaagatcactaaccacctggtagcgatgattgaaaagaccattggcggccaggatgcc
ctccccaatattgccgacgccgaacgcatttttgccgaacttcttcagggccttgccgac
gcccagcccgctttcccgcttgcccagttaaaagccttcgtggagcaggaatttgctcag
attaagcatgttctgcacggcatcagcctgctgggtcagtgcccggacagcgtcaatgcc
gcgctgatctgccgcggcgaaaagctctccatcgccatcatggcgggtctgctggaagcc
cgtggacataaagtcagtgtcattaacccggtcgaaaaactgcttgccgtgggccactat
ctggaatccaccgtcgatatcgccgaatccacccgccgcattgccgccagccagatcccg
gcagaccatatgatcctgatggccgggtttaccgccggcaatgagaaaggcgagctggtg
gtgctggggcgtaacggctccgactactcggctgcggtactggccgcctgcctgcgcgct
gactgctgcgaaatctggaccgatgtcgacggagtgtacacctgcgatccgcgtcaggtg
ccggatgcgcgcctgctgaaatcgatgtcttatcaggaggcgatggagctctcctacttt
ggcgcgaaagtgctgcacccgcgcaccatcgcccctatcgcccagttccaaatcccatgc
ctgattaaaaataccggcaacccgcaggcgccgggaacgcttatcggcgccagccgcgac
gaggacgatttgccggtgaaaggcatctctaacctcaacaacatggcgatgttcaacgtc
tccgggccggggatgaaagggatggtcggcatggcggcccgcgtcttcgccaccatgtcc
cgcgccggcatctcggtggtgctgatcactcaatcttcttccgagtacagcatcagtttc
tgcgtgccgcagagcgactgcgcacgtgccaaacgggcgatggaagatgagttttatctg
gagctgaaagaggggctgctggagccgctggcgattatggagcgtctggcgatcatctcc
gtggtgggcgacggaatgcgtaccctgcgcggtatctcggcgaaattctttgcggcactg
gcccgcgccaatatcaatatcgtggcgattgcccagggctcttccgagcgctcaatttcg
gtagtggtcagcaatgacgacgccaccaccggcgtgcgcgtgacccatcagatgctgttc
aataccgaccaggtgattgaagtgtttgtcatcggcgtcggcggcgtcggcggcgcgctg
ctagagcagatcaagcgccagcaggggtggctgaagaacaaacatatcgatctgcgcgtc
tgcggtgtagccaattctcaggcgctgctgaccagcgtgcatggcctgaatctggaaaac
tggagtgcggaactggcggaggcgaaagagccgtttaatcttggccgcctgatccgcctg
gtgaaagagtaccacctgctcaatccggtgatcgtagactgtacctccagccaggcggtc
gccgatcagtatgccgacttcctgcgcgaaggtttccatgtggtgacgccgaacaaaaag
gccaatacctcttcgctggattactatcaccagctgcgccatgcggccagcagctcgcgg
cgtaagttcctctatgacactaacgttggcgcgggcctgccggtgattgagaacctgcag
aacctgctcaacgccggcgatgagctgcgccatttctccgggatcctgtccggctccctg
tcgtttatcttcggcaagctggacgagggggtgagtttctccgcggcgacggcgatggcc
cgtgagatggggtataccgagccggatccgcgcgacgatttatccggggtggatgtggcg
cgtaaactgctgattctggcccgtgagaccgggcgtgaactggagctggcggacattatc
gtcgagtcggcgctgccgccggacttcgacgccagcggcgatgtcgagacctttatggcc
cgcctgccgtcgctggacgatggttttgcctcgcgggttgctaaggcgcgcgatgaaggt
aaagtcttgcgctacgtcggtaacatcgaagaggatggtacctgccgggtaaaaatagcc
gcggttgacggcaacgatccgctgttcaaagttaagaatggtgagaacgcgctggctttt
tatagccattattatcagccattgccgctggtgctgcgcggctatggcgccgggaacgac
gtcacggcggccggcgtattcgccgacctgctgcgcaccctgtcctggaagttaggagtt
taa
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