Klebsiella pneumoniae subsp. pneumoniae KPNIH30: KPNIH30_04240
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Entry
KPNIH30_04240 CDS
T03466
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpw
Klebsiella pneumoniae subsp. pneumoniae KPNIH30
Pathway
kpw00290
Valine, leucine and isoleucine biosynthesis
kpw00620
Pyruvate metabolism
kpw01100
Metabolic pathways
kpw01110
Biosynthesis of secondary metabolites
kpw01210
2-Oxocarboxylic acid metabolism
kpw01230
Biosynthesis of amino acids
Module
kpw_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpw00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPNIH30_04240
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPNIH30_04240
Enzymes [BR:
kpw01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPNIH30_04240
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
AIX77468
UniProt:
A0A422VJS4
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All DBs
Position
complement(845702..847273)
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
ITRTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEY
ANIISGLYDRVPNIDKAIISVHTHDDLGIAVGNALAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYQESDYNLDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFNVQSGSSDIATASIKLVCGDEIKT
EAANGNGPVDAIYQAINRVTDYNIELVKYGLSAKGHGKDALGQVDIVVDYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgatacgaccttacgtgatggcgaacaagcgttacag
gcaagcctgagtgtcaaagagaagctgcagatcgcactggcccttgagcgaatgggggtc
gacgtaatggaagtcggtttcccggtatcctcgccgggcgattttgaatcggtgcaaacc
atcacgcgcaccattaaaaacagccgcgtgtgcgccctggcgcgctgcgttgagaaagat
atcgacgtggcggcggaatcgttaaaagtggccgaggctttccgtattcatacctttatt
gccacctcgccgatgcatatcgccaccaaactgcgcagtacgctggatgaggttattgag
cgcgcgatctatatggtgaagcgggcacgcaactacactgacgacgttgagttctcctgt
gaagacgccggccgtacgccgattgccgatctggctcgcgtcgtggaagcggcgatcaac
gccggcgccaccaccattaatatcccggataccgtcggctataccatgccgttcgaatat
gccaacatcatcagcggcctgtatgatcgcgtgccgaatatcgacaaagcaattatttcc
gtccacacccatgatgatctgggcatcgctgtcggtaacgccctcgccgcggtccacgcc
ggtgcgcgccaggtagaaggtgcgatgaacggtatcggcgaacgcgccggcaactgcgca
ctggaagaagtgatcatggcgatcaaagtgcgcaaagacatcatgaacgtgcacaccaac
attaatcatcatgaaatctggcgcaccagccagaccgtcagccagatctgcaatatgccg
atcccggcgaacaaggccatcgtcggcaccggcgccttcgcccactcctccggcattcac
caggacggcgtgctgaagaaccgcgaaaactacgagatcatgaccccggaatctatcggc
ctgaaccaggtgcaactgaacctgacttcccgctccggccgcgcggcggtgaaacaccgg
atggaagagatgggctaccaggagagcgattacaacctggatcatctgtacgacgcattc
ctgaagctggcggacaaaaaaggccaggtcttcgattacgatctggaagcgctggccttt
atcaacaagcagcaggaagagccagagcatttccgcctggattacttcaacgtccaatcc
ggatccagcgatatcgccaccgcctcgatcaaactggtctgcggggatgagatcaaaacc
gaagccgccaacggcaacggtccggtcgatgctatctaccaggcgattaatcgcgtcacc
gactacaacattgaattagtgaagtatggcttaagcgcgaaaggccacggcaaagacgcc
ctgggccaggtggatatcgtcgttgactacaatggccgccgcttccatggcgttggtctg
gcaacggatatcgtagagtcgtcagccaaagcgatggttcacgtgctgaacaacatctgg
cgcgccgccgaagtcgaaaaagaattgcaacgcaaagctcagaataaagagaacaataag
gaaaccgtgtaa
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