Klebsiella pneumoniae PMK1: PMK1_ndm00067
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Entry
PMK1_ndm00067 CDS
T03419
Symbol
blaNDM-1_1
Name
(GenBank) Beta-lactamase NDM-1 precursor
KO
K18780
metallo-beta-lactamase class B NDM [EC:
3.5.2.6
]
Organism
kpx
Klebsiella pneumoniae PMK1
Pathway
kpx01501
beta-Lactam resistance
Module
kpx_M00851
Carbapenem resistance
Brite
KEGG Orthology (KO) [BR:
kpx00001
]
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
PMK1_ndm00067 (blaNDM-1_1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
01504 Antimicrobial resistance genes [BR:
kpx01504
]
PMK1_ndm00067 (blaNDM-1_1)
Enzymes [BR:
kpx01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.6 beta-lactamase
PMK1_ndm00067 (blaNDM-1_1)
Antimicrobial resistance genes [BR:
kpx01504
]
Gene variants
beta-Lactamase genes
Class B [MT]
PMK1_ndm00067 (blaNDM-1_1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Lactamase_B
Lactamase_B_2
Motif
Other DBs
NCBI-ProteinID:
AIT04839
UniProt:
E9NWK5
Structure
PDB
PDBj
LinkDB
All DBs
Position
pPMK1-NDM:47947..48759
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AA seq
270 aa
AA seq
DB search
MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQRFGDLVFRQLAPNVWQ
HTSYLDMPGFGAVASNGLIVRDGGRVLVVDTAWTDDQTAQILNWIKQEINLPVALAVVTH
AHQDKMGGMDALHAAGIATYANALSNQLAPQEGMVAAQHSLTFAANGWVEPATAPNFGPL
KVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSLGNLGDADTEHYAASARAFGAAF
PKASMIVMSHSAPDSRAAITHTARMADKLR
NT seq
813 nt
NT seq
+upstream
nt +downstream
nt
atggaattgcccaatattatgcacccggtcgcgaagctgagcaccgcattagccgctgca
ttgatgctgagcgggtgcatgcccggtgaaatccgcccgacgattggccagcaaatggaa
actggcgaccaacggtttggcgatctggttttccgccagctcgcaccgaatgtctggcag
cacacttcctatctcgacatgccgggtttcggggcagtcgcttccaacggtttgatcgtc
agggatggcggccgcgtgctggtggtcgataccgcctggaccgatgaccagaccgcccag
atcctcaactggatcaagcaggagatcaacctgccggtcgcgctggcggtggtgactcac
gcgcatcaggacaagatgggcggtatggacgcgctgcatgcggcggggattgcgacttat
gccaatgcgttgtcgaaccagcttgccccgcaagaggggatggttgcggcgcaacacagc
ctgactttcgccgccaatggctgggtcgaaccagcaaccgcgcccaactttggcccgctc
aaggtattttaccccggccccggccacaccagtgacaatatcaccgttgggatcgacggc
accgacatcgcttttggtggctgcctgatcaaggacagcaaggccaagtcgctcggcaat
ctcggtgatgccgacactgagcactacgccgcgtcagcgcgcgcgtttggtgcggcgttc
cccaaggccagcatgatcgtgatgagccattccgcccccgatagccgcgccgcaatcact
catacggcccgcatggccgacaagctgcgctga
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