Klebsiella pneumoniae subsp. pneumoniae KPNIH31: KPNIH31_00640
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Entry
KPNIH31_00640 CDS
T03467
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
kpy
Klebsiella pneumoniae subsp. pneumoniae KPNIH31
Pathway
kpy00290
Valine, leucine and isoleucine biosynthesis
kpy00770
Pantothenate and CoA biosynthesis
kpy01100
Metabolic pathways
kpy01110
Biosynthesis of secondary metabolites
kpy01210
2-Oxocarboxylic acid metabolism
kpy01230
Biosynthesis of amino acids
Module
kpy_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
kpy_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
kpy00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPNIH31_00640
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
KPNIH31_00640
Enzymes [BR:
kpy01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
KPNIH31_00640
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
AIX82222
UniProt:
A0A235U1A4
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Position
132502..134352
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AA seq
616 aa
AA seq
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MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFTQFVPGHVHLRDLGKLV
AEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIADSVEYMVNAHCADAMVCIS
NCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDKIIKLDLVDAMIQGADPKVSDEQ
SNQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGNGSLLATHADRKELFLNAGKRIV
ELTKRYYEQDDASALPRNIASKAAFENAMTLDIAMGGSTNTVLHLLAAAQEAEIDFTMSD
IDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVLGILGELDRAGLLNREVKNVLGLTLPQT
LEQYDVMVTQDDAVKKMFRAGPAGIRTTQAFSQDCRWDTLDDDRAEGCIRSLEHAYSKDG
GLAVLYGNFAENGCIVKTAGVDDSILKFTGPAKVYESQDDAVEAILGGKVVEGDVVVIRY
EGPKGGPGMQEMLYPTSFLKSMGLGKACALITDGRFSGGTSGLSIGHVSPEAASGGNIAL
IEDGDMIAIDIPNRSIQLQLSDAEIAARREAQEARGDQAWTPKNRQRQVSFALRAYASLA
TSADKGAVRDKSKLGG
NT seq
1851 nt
NT seq
+upstream
nt +downstream
nt
atgcctaagtaccgttccgccaccaccacacatggccgcaatatggcgggcgcccgcgcg
ttgtggcgcgcaaccggaatgaccgatgccgatttcggcaaaccgattatcgccgtcgtt
aactcctttacccagtttgtccccgggcacgtgcacctgcgcgatctcggcaaactggtt
gccgagcagattgaagccgccggtggcgtggccaaagaattcaacaccatcgcagtggat
gatgggatcgctatgggccacgggggtatgctctattcactgccatcccgcgagctgatc
gccgactcggtggagtatatggttaacgcccactgcgctgatgccatggtttgtatctcc
aactgcgacaaaatcaccccggggatgctgatggcctccctgcgcctgaacattccggtg
atctttgtttccggcggcccgatggaagccgggaagaccaagttgtcagataaaatcatc
aagcttgacctggtggatgcgatgattcagggggcggatccgaaagtgtccgacgagcag
agtaatcaggtggaacgctccgcctgcccgacctgcggctcctgttccgggatgttcacg
gcgaactccatgaactgcctgaccgaagcgctgggcctgtcacagccgggcaacggctct
ctgctggcgacccacgccgatcgtaaggagctgttcctaaacgccgggaaacgtatcgtg
gagctgaccaaacgctattacgagcaggatgacgcttccgcgctgccgcgcaatatcgcc
agcaaggcggcctttgagaacgctatgacgctggatatcgccatgggcggctccaccaat
accgttctgcacctgctggcggcggcgcaggaagctgaaatcgacttcaccatgagcgat
atcgataagctctcccgcaaagtgccgcagctgtgtaaggtggcgccgagcacgcagaaa
taccatatggaagatgtgcatcgcgccggcggcgtgctgggcattctgggcgagctggac
cgcgccgggctgctgaatcgcgaggtcaaaaacgtccttggcctgacgctgccgcagacc
ctggaacagtacgatgtgatggtgacccaggacgatgcggtgaaaaaaatgttccgcgcc
ggcccggcgggcatccgtaccacccaggcgttctcgcaagactgccgctgggataccctg
gatgacgatcgcgccgaaggctgtatccgttctctggaacacgcttacagcaaggacggc
ggcctggcggtgctgtacggcaatttcgcagaaaacggttgtatcgtgaaaaccgccggc
gtggacgacagcatcctgaaatttaccggtccggcgaaagtatatgagagccaggacgat
gcggttgaggccatcctcggcggtaaagtcgtggaaggcgacgtcgtggtgatccgctac
gaagggccgaaaggcgggccggggatgcaggaaatgctttaccccaccagcttcctgaag
tcgatggggctgggcaaagcgtgcgcgctgatcaccgatggccgtttctccggcggcacc
tcagggctctctatcggtcacgtctctccggaagcggcgagcggcggcaacattgcgctc
attgaagatggcgacatgatcgcgattgatattccgaaccgcagcatccagctgcagctg
agcgatgcggaaattgcggcgcgtcgtgaagcccaggaggcgcgtggcgaccaggcgtgg
acgccgaagaatcgccagcgtcaggtctcctttgcccttcgcgcctacgccagcctggcg
accagcgccgacaaaggcgcggtacgcgataaatccaagctgggtggctaa
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