Klebsiella pneumoniae subsp. pneumoniae KPNIH31: KPNIH31_03740
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Entry
KPNIH31_03740 CDS
T03467
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
kpy
Klebsiella pneumoniae subsp. pneumoniae KPNIH31
Pathway
kpy00300
Lysine biosynthesis
kpy00550
Peptidoglycan biosynthesis
kpy01100
Metabolic pathways
kpy01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
kpy00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
KPNIH31_03740 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
KPNIH31_03740 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
KPNIH31_03740 (murF)
Enzymes [BR:
kpy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
KPNIH31_03740 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
YAcAr
LpxD
Motif
Other DBs
NCBI-ProteinID:
AIX82774
UniProt:
A0A2W0NX35
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Position
complement(760609..761967)
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AA seq
452 aa
AA seq
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MIRFTLSQLAAIAHGERQGSDVAIDEVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKAA
GAGALLVSRPLACDLPQVIVNDTRQAFGELAAWVRQQVPTRVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHQYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIYTGLPENGIAILNADNNDWLNWQAVIGDRKVWRFS
PNAANSDFTATNVQITSHGTEFTLQTPTGNVDVLLPLPGRHNIANALAATSLAMAVGADL
AAVKAGLAQLQAVPGRLFPIRLTESQLLLDDSYNANVGSMTAAVQVLSEMPGFRTMVVGD
MAELGAESAACHREVGEAAKAAGLDCVLSVGALSADISRASGVGEHFNDKAAVVARLREL
LAEHKIMTILVKGSRSAAMEEVVRALQETGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattcgctttacgttaagtcaacttgccgcgatcgcccatggcgaacggcagggtagc
gatgtcgctatcgacgaggtgaccaccgatacccgtaaagtgacggcgggctgcctgttt
gtggcgctgaaaggggagcgtttcgacgcccatgattttgccgaacaggcgaaagcggcg
ggcgccggcgcgctgctggtgagtcgtccgctggcctgcgatctcccgcaggtgattgtg
aacgatacccggcaggctttcggtgagttagccgcctgggtgcgtcagcaggtgccgact
cgcgtcgtcgccctgaccggctcgtccggtaaaacctcggttaaagagatgaccgcggcg
atcctcagccagtgcggcaacacactgtataccgccggcaacctgaacaacgatatcggc
gtcccgatgacgttgctgcggctgaccaaagagcatcagtacgcggtgatcgaactcggc
gccaaccaccagggcgaaatcgcctggaccgtcagcctgacgcgtccggaagcggcgctg
gtcaacaaccttgctgcggcgcacctggaaggtttcggttcgctggcgggcgtggcgaag
gcgaagggcgaaatctataccggtctgccggaaaatggcatcgccatcctcaatgccgac
aataacgactggctgaactggcaggcggtgattggcgatcgcaaagtgtggcgcttctcg
ccgaacgcggcgaacagcgatttcacggcgaccaatgtgcagatcaccagccacggcacc
gaatttacgctgcagaccccaaccggtaacgttgacgtactgctgccgctgccgggacgc
cacaacatcgctaatgcgctggccgccacttcgctggcgatggcggtaggcgccgatttg
gcggcggtgaaagccggactggcgcagctgcaggccgttccgggacgtctgttcccgatc
cggctgaccgagagccagctgctgctggatgattcctataacgctaacgttggttcgatg
accgcggcggtgcaggtgctgtcagagatgcccggctttcgcacgatggtggtcggcgat
atggcagagcttggcgcggagagcgcggcctgccatcgcgaagtcggcgaagcggcgaaa
gcggcgggtctggattgcgtcctcagcgtcggcgccttgagcgcggatatcagccgcgcc
agcggcgtgggcgaacattttaacgataaagccgccgtggtggctcgcctgcgcgagctg
ctggcggagcacaaaataatgaccattttagtgaagggttcacgtagtgccgccatggaa
gaggtagtacgcgcattacaggagactgggacatgttag
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