Klebsiella pneumoniae subsp. pneumoniae KPNIH31: KPNIH31_03795
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Entry
KPNIH31_03795 CDS
T03467
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kpy
Klebsiella pneumoniae subsp. pneumoniae KPNIH31
Pathway
kpy00290
Valine, leucine and isoleucine biosynthesis
kpy00620
Pyruvate metabolism
kpy01100
Metabolic pathways
kpy01110
Biosynthesis of secondary metabolites
kpy01210
2-Oxocarboxylic acid metabolism
kpy01230
Biosynthesis of amino acids
Module
kpy_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kpy00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KPNIH31_03795
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KPNIH31_03795
Enzymes [BR:
kpy01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KPNIH31_03795
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
IPMS_D2
Trp_syntA
Motif
Other DBs
NCBI-ProteinID:
AIX82785
UniProt:
A0A1Y0Q3J1
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All DBs
Position
773187..774758
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AA seq
523 aa
AA seq
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MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVMEVGFPVSSPGDFESVQT
IARTIKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIATSPMHIATKLRSTLDEVIE
RAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAINAGATTINIPDTVGYTMPFEY
ANIISGLYDRVPNIDKAIISVHTHDDLGIAVGNALAAVHAGARQVEGAMNGIGERAGNCA
LEEVIMAIKVRKDIMNVHTNINHHEIWRTSQTVSQICNMPIPANKAIVGTGAFAHSSGIH
QDGVLKNRENYEIMTPESIGLNQVQLNLTSRSGRAAVKHRMEEMGYQESDYNLDHLYDAF
LKLADKKGQVFDYDLEALAFINKQQEEPEHFRLDYFNVQSGSSDIATASIKLVCGDEIKT
EAANGNGPVDAIYQAINRVTDYNIELVKYGLSAKGHGKDALGQVDIVVDYNGRRFHGVGL
ATDIVESSAKAMVHVLNNIWRAAEVEKELQRKAQNKENNKETV
NT seq
1572 nt
NT seq
+upstream
nt +downstream
nt
atgagccagcaagtcattattttcgatacgaccttacgtgatggcgaacaagcgttacag
gcaagcctgagtgtcaaagagaagctgcagatcgcactggcccttgagcgaatgggggtc
gacgtaatggaagtcggtttcccggtatcctcgccgggcgattttgaatcggtgcaaacc
atcgcacgcaccattaaaaacagccgcgtgtgcgctctggcgcgctgcgttgagaaagat
atcgacgtggcggcggaatcgttaaaagtggccgaggctttccgtattcatacctttatt
gccacctcgccgatgcatatcgccaccaaactgcgcagtacgctggatgaggttattgag
cgcgcgatctatatggtgaagcgggcacgcaactacactgacgacgttgagttctcctgt
gaagacgccggccgtacgccgattgccgatctggctcgcgtcgtggaagcggcgatcaac
gccggcgccaccaccattaatatcccggataccgtcggctataccatgccgttcgaatat
gccaacatcatcagcggcctgtatgatcgcgtgccgaatatcgacaaagcaattatttcc
gtccacacccatgatgatctgggcatcgctgtcggtaacgccctcgccgcggtccacgcc
ggtgcgcgccaggtagaaggtgcgatgaacggtatcggcgaacgcgccggcaactgcgcg
ctggaagaagtgatcatggcgatcaaagtgcgcaaagacatcatgaacgtgcacaccaac
attaatcatcatgaaatctggcgcaccagccagaccgtcagccagatctgcaatatgccg
atcccggcgaacaaggccatcgtcggcaccggcgccttcgcccactcctccggcattcac
caggacggcgtgctgaagaaccgcgaaaactacgagatcatgaccccggaatctatcggc
ctgaaccaggtgcaactgaacctgacttcccgctccggccgcgcggcggtgaaacaccgg
atggaagaaatgggctaccaggagagcgattacaacctggatcatctgtacgacgcattc
ctgaagctggcggacaaaaaaggccaggtcttcgattacgatctggaagcgctggccttt
atcaacaagcagcaggaagagccagagcatttccgcctcgattacttcaacgtccaatcc
ggatccagcgatatcgccaccgcctcgatcaaactggtctgcggggatgagatcaaaacc
gaagccgccaacggcaacggtccggtcgatgctatctaccaggcgattaaccgcgtcacc
gactacaacattgaattagtgaagtatggcttaagcgcgaaaggccacggcaaagacgcc
ctgggccaggtggatatcgtcgttgactacaatggccgccgcttccatggcgttggtctg
gcaacggatatcgtagagtcgtcagccaaagcgatggttcacgtgctgaacaacatctgg
cgcgccgccgaagtcgaaaaagaattgcaacgcaaagctcagaataaagagaacaataag
gaaaccgtgtaa
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