Klebsiella pneumoniae subsp. pneumoniae KPNIH27: KPNIH27_03665
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Entry
KPNIH27_03665 CDS
T03370
Symbol
carB
Name
(GenBank) carbamoyl phosphate synthase large subunit
KO
K01955
carbamoyl-phosphate synthase large subunit [EC:
6.3.5.5
]
Organism
kpz
Klebsiella pneumoniae subsp. pneumoniae KPNIH27
Pathway
kpz00220
Arginine biosynthesis
kpz00240
Pyrimidine metabolism
kpz00250
Alanine, aspartate and glutamate metabolism
kpz01100
Metabolic pathways
kpz01110
Biosynthesis of secondary metabolites
kpz01240
Biosynthesis of cofactors
Module
kpz_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
kpz00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
KPNIH27_03665 (carB)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
KPNIH27_03665 (carB)
00220 Arginine biosynthesis
KPNIH27_03665 (carB)
Enzymes [BR:
kpz01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
KPNIH27_03665 (carB)
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Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D1
CPSase_L_D3
MGS
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
ATP-grasp_4
ATPgrasp_Ter
Radical_SAM
CoA_binding_2
BamE
Motif
Other DBs
NCBI-ProteinID:
AIA40448
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All DBs
Position
772191..775415
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AA seq
1074 aa
AA seq
DB search
MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRVILVNSNPATIMTDPEM
ADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALELERQGVLAEFGVTMIGATA
DAIDKAEDRRRFDIAMKKIGLDTARSGIAHTMEEALAVAADVGFPCIIRPSFTMGGTGGG
IAYNREEFEEICERGLDLSPTNELLIDESLIGWKEYEMEVVRDKNDNCIIVCSIENFDAM
GIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIGVETGGSNVQFAVNPKNGRLIVIEM
NPRVSRSSALASKATGFPIAKVAAKLAVGYTLDELMNDITGGRTPASFEPSIDYVVTKIP
RFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQESLQKALRGLEVGATGFDPKVSLDDPEA
LTKIRRELKDAGAERIWYIADAFRAGLSVDGVFNLTNIDRWFLVQIEELVRLEEKVAEVG
INGLDADFLRTLKRKGFADARLAKLAGVREAEIRKLRDQYDLHPVYKRVDTCAAEFATDT
AYMYSTYEEECESNPSVDRDKIMVLGGGPNRIGQGIEFDYCCVHASLALREDGYETIMVN
CNPETVSTDYDTSDRLYFEPVTLEDVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVP
VIGTSPDAIDRAEDRERFQHAVDRLKLKQPANATVTAIEQAVEKAKEIGYPLVVRPSYVL
GGRAMEIVYDEQDLRRYFQTAVSVSNDAPVLLDRFLDDAIEVDVDAICDGEMVLIGGIME
HIEQAGVHSGDSACSLPAYTLSKEIQDVMREQVQKLAFELQVRGLMNVQFAVKDNEVYLI
EVNPRAARTVPFVSKATGVPLAKVAARVMAGKTLAQQGVTKEIIPPYYSVKEVVLPFNKF
PGVDPLLGPEMRSTGEVMGVGRTFAEAFAKAQLGSNSTMKKQGRALLSVREGDKERVVDL
AAKLLKFGFELDATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTAGR
QAIEDSKLIRRSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQITK
NT seq
3225 nt
NT seq
+upstream
nt +downstream
nt
atgccaaaacgtacagacataaaaagtatcctgattctgggcgcgggcccgattgttatc
ggtcaggcgtgtgagtttgactactccggcgcccaggcctgtaaagcgctgcgcgaagag
ggctaccgcgttatcctggtgaactctaacccggcgaccatcatgaccgacccggaaatg
gccgatgccacctacatcgagccgattcactgggaagtggtgcgtaaaatcatcgaaaaa
gagcgcccggatgcggtgctgccgaccatgggcggccagacggcgctgaactgcgcgctc
gagctggagcgtcagggggtcctggctgaattcggcgtgaccatgattggcgccaccgcc
gatgcgattgataaagccgaagaccgtcgccgtttcgatatcgcaatgaaaaaaatcggc
ctcgacaccgcgcgctctggtatcgcccacacgatggaagaggcgctggcggttgccgcc
gacgttggtttcccgtgcatcatccgtccgtccttcaccatgggcggcaccggcggcggt
atcgcctataaccgcgaagagttcgaagaaatctgcgaacgcggcctggatctctctccg
accaacgaactgctgatcgatgaatcgctgatcggctggaaagagtacgagatggaagtg
gtgcgcgataagaacgacaactgcatcatcgtctgctccatcgaaaacttcgacgccatg
gggatccacaccggtgactccatcaccgttgccccggcgcagaccctgaccgacaaagag
taccagatcatgcgtaacgcctcgatggcggtgctgcgtgaaatcggcgtcgaaaccggc
ggctctaacgtgcagttcgcggtcaacccgaaaaacggtcgcctgatcgttatcgaaatg
aacccgcgcgtctcccgctcctcggcgctggcctctaaggccaccggcttcccgattgct
aaagtggcagccaagctggcggtaggttatacccttgacgagctgatgaacgacatcacc
ggcggccgcaccccggcttcctttgaaccgtccatcgactacgtggtcactaaaatccca
cgctttaactttgaaaaattcgccggcgccaacgaccgtctgaccacccagatgaagtct
gtcggcgaagtgatggcgattggccgtacccagcaggaatccttgcagaaagcgctgcgc
ggtctggaagtgggcgctaccggcttcgacccgaaagtgagcctcgacgacccggaagcg
ctgaccaaaatccgccgcgagctgaaagatgccggcgctgagcgtatctggtatatcgct
gacgcgttccgcgcgggcctctcggttgacggcgtcttcaacctgaccaacatcgaccgc
tggttcctggtacagattgaagagctggtccgtctggaagagaaagtggcggaagtgggc
atcaacggcctcgacgctgacttcctgcgcaccctgaagcgtaaaggctttgccgatgcg
cgtctggcgaagctggcgggcgtgcgggaagcggaaatccgcaagctgcgcgaccagtat
gacctgcacccggtctacaagcgcgtggacacctgcgctgcggaatttgctaccgatacc
gcctacatgtactccacttatgaagaagagtgtgagtccaacccgtccgttgaccgcgat
aaaatcatggtcctcggcggcggcccgaaccgtatcggtcagggtatcgaattcgactac
tgctgcgtacacgcctcgctggcgctgcgcgaggacggttacgagaccatcatggtcaac
tgtaacccggaaaccgtctctaccgactacgacacctccgaccgtctgtattttgagccg
gtgaccctggaagacgtgctggaaatcgtgcgcatcgagaagccaaaaggcgttatcgtc
cagtacggcggccagaccccgctgaagctggctcgtgccctggaagctgccggcgtgccg
gttatcggtaccagtccggacgctatcgaccgggcggaagaccgtgagcgcttccagcac
gcggttgaccgtctgaagctgaagcagccggcgaacgccaccgtcaccgccattgagcag
gcggtagagaaagcgaaagagattggctacccgctggtggtgcgtccgtcttatgtgctc
ggcggccgggcgatggagatcgtctatgacgagcaggatctgcgccgctacttccagacc
gcggtcagcgtctccaacgacgcgccggtgctgctggatcgcttcctcgacgatgcgatt
gaagtggatgtcgatgccatctgcgatggcgaaatggtgctgattggcggcatcatggag
catatcgagcaggcaggcgtccactccggcgactccgcctgttccctgccagcctacacc
ctgagcaaagagattcaggatgtgatgcgcgagcaggtgcagaagctggccttcgagttg
caggttcgtggcctgatgaacgtccagttcgcggtgaaagataacgaagtttatctgatt
gaggtcaacccgcgtgcggcgcgtaccgtaccgttcgtctccaaagccaccggcgtcccg
ctggcgaaagtggcggcgcgcgtgatggccggtaagacactggcgcagcagggcgtgacc
aaagagatcatcccgccgtattactcggtgaaagaggtggtcctgccgttcaataaattc
ccgggcgttgacccgctgttagggccagaaatgcgctccaccggggaagtgatgggcgtc
ggccgcacctttgccgaagcgttcgccaaagcgcagctgggcagcaactcgaccatgaag
aaacagggtcgcgcgctgctctccgtccgcgaaggcgataaagagcgcgtggttgacctg
gcggcgaagctgctgaagtttggcttcgagctggatgcgactcacggtacggcgattgtg
ctgggtgaagcgggcattaacccgcgtctggtgaacaaggtgcatgaaggtcgtccgcac
attcaggaccgcatcaagaatggcgaatatacctacatcatcaacaccaccgcaggtcgc
caggcgattgaagactccaagctgattcgccgcagcgcgctgcagtacaaagtgcattac
gacaccaccctgaacggcggctttgccaccgcgatggcgctgaacgctgacgccaccgag
aaggtgatttcggtgcaggaaatgcacgcgcaaatcactaaataa
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