Kitasatospora setae: KSE_25470
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Entry
KSE_25470 CDS
T01648
Symbol
leuA
Name
(GenBank) putative 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ksk
Kitasatospora setae
Pathway
ksk00290
Valine, leucine and isoleucine biosynthesis
ksk00620
Pyruvate metabolism
ksk01100
Metabolic pathways
ksk01110
Biosynthesis of secondary metabolites
ksk01210
2-Oxocarboxylic acid metabolism
ksk01230
Biosynthesis of amino acids
Module
ksk_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ksk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
KSE_25470 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
KSE_25470 (leuA)
Enzymes [BR:
ksk01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
KSE_25470 (leuA)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
BAJ28360
UniProt:
E4NAX9
LinkDB
All DBs
Position
complement(2835408..2837192)
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AA seq
594 aa
AA seq
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MTEQSSVARPFVDRPTPITAATVQQKPSGMPFRRYVPFGTVDLPDRTWPSKVITQAPRWL
STDLRDGNQALIDPMSPARKRKMFDLLVKMGYKEIEVGFPSSGATDFNFVRSLIDEGAIP
EDVTISVLTQAREDLIERTVESLKGAPRATVHLYNATSPLFRRVVFRAGKEEIKAIAVDG
TRLVMEYAEKILGDETVFGYEYSPEIFIDTELDYALEVCEAVMDVWQPGEGREIILNLPT
TVERSTPNVYADKIEWMSRNLSRREFVCLSTHPHNDRGTGVASAELAVMAGADRVEGCLF
GQGERTGNLDLVNVGMNLFSQGVDPMIDFSDIDEIRRTAEYCNQMPVAERHPYAGDLVFT
SFSGSHQDAIKKGFDALEADAAAAGVPVGEHTWGVPYLPIDPKDVGRSYEAVIRVNSQSG
KGGIAYVLKNDHKLDLPRRMQIEFSRIIQAKTDAEGGEVTPAAIWAVFQDEYLPTPANPW
GRISLSGSRSLTTEDGRDALSTEAVVDGTPITLTGTGNGPVSAFVNALASIGVDVRVLDY
AEHALSEGGDAQAAAYVECAVGDKVLWGVGIDGNTVLASLKALVSAVNRAAQRD
NT seq
1785 nt
NT seq
+upstream
nt +downstream
nt
atgaccgaacagtcctccgtcgcccgcccgttcgtcgaccgccccaccccgatcaccgcc
gccaccgtgcagcagaagccctcggggatgcccttccggcgctacgtgccgttcggcacc
gtcgacctgccggaccgcacctggccgagcaaggtgatcacgcaggccccgcgctggctc
tccaccgacctgcgcgacggcaaccaggcgctgatcgacccgatgtcgccggcccgcaag
cgcaagatgttcgacctgctggtgaagatgggctacaaggagatcgaggtcggcttcccc
tcctccggggccaccgacttcaacttcgtccgttcgctgatcgacgagggcgcgatcccc
gaggacgtcaccatctcggtgctgacccaggcccgcgaggacctgatcgagcgcaccgtg
gagtcgctgaagggcgcgccgcgggccaccgtgcacctgtacaacgcgacctcaccgctg
ttccgccgggtggtgttccgggcggggaaggaggagatcaaggccatcgcggtggacggc
acccgcctggtgatggagtacgccgagaagatcctgggcgacgagacggtcttcggctac
gagtactcgccggagatcttcatcgacaccgagctggactacgcgctggaggtctgcgag
gcggtgatggacgtctggcagcccggcgagggccgcgagatcatcctgaacctgccgacc
accgtcgagcgctccaccccgaacgtctacgccgacaagatcgagtggatgtcgcggaac
ctgtcgcgccgcgagttcgtctgcctgtccacccacccgcacaacgaccggggcaccggc
gtggcctccgccgagctggccgtgatggccggtgccgaccgggtcgagggctgcctgttc
gggcagggcgagcgcaccggcaacctggacctggtcaacgtcgggatgaacctgttctcc
cagggcgtcgacccgatgatcgacttctcggacatcgacgagatccgccgcaccgccgag
tactgcaaccagatgccggtggccgagcgccacccctacgcgggcgacctggtcttcacc
tccttctccggctcgcaccaggacgcgatcaagaagggcttcgacgccctggaggccgac
gcggccgccgccggcgtcccggtcggcgagcacacctggggcgtgccctacctgccgatc
gacccgaaggacgtcggccgcagctacgaggcggtcatccgggtcaactcgcagtccggc
aagggcggcatcgcctacgtcctgaagaacgaccacaagctggacctgccgcgccggatg
cagatcgagttctcgcggatcatccaggccaagaccgacgccgagggcggcgaggtcact
cccgccgccatctgggcggtcttccaggacgagtacctgccgaccccggccaacccgtgg
ggccggatctcgctgagcggctcccgcagcctgaccaccgaggacggccgcgacgcgctg
agcaccgaggccgtcgtcgacggcaccccgatcaccctgaccggcaccggcaacggcccg
gtctccgccttcgtcaacgcgctggcctcgatcggcgtggacgtccgagtactggactac
gccgagcacgcgctgagcgagggcggcgacgcgcaggccgccgcgtacgtcgagtgcgcc
gtcggcgacaaggtgctgtggggcgtgggcatcgacggcaacaccgtgctggcctcgctg
aaggccctggtcagcgccgtcaaccgggcggcccagcgcgactga
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