Candidatus Kinetoplastidibacterium kentomonadis: CKSOR_00009
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Entry
CKSOR_00009 CDS
T05428
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
kso
Candidatus Kinetoplastidibacterium kentomonadis
Pathway
kso00290
Valine, leucine and isoleucine biosynthesis
kso00620
Pyruvate metabolism
kso01100
Metabolic pathways
kso01110
Biosynthesis of secondary metabolites
kso01210
2-Oxocarboxylic acid metabolism
kso01230
Biosynthesis of amino acids
Module
kso_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
kso00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
CKSOR_00009 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CKSOR_00009 (leuA)
Enzymes [BR:
kso01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
CKSOR_00009 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
Motif
Other DBs
NCBI-ProteinID:
AWD32156
UniProt:
A0A3Q8EXW1
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All DBs
Position
complement(12006..13679)
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AA seq
557 aa
AA seq
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MLTNPSKKYVPFRPFKKDFSERTWPSKIITKAPIWMTTDLRDGNQSLVDPMSTHQKLRFF
DQLIKIGFKEIEIGFPSASQIEFDFIRKLIEEERIPDDVTIILLTQAREDLIKRTVESAI
GAKNIMIHMYNSCAPSFRKIVFRMTRDEIKNLAIHGTELVRNYTSLYPKTEWRFEYSPEV
FSTTELDFALDISNAVIDTWKPISTNKMVLNLPSTIESNTPNIYADQIEWMHNNLSHRDK
ILLSVHPHNDRGTSVAAAELSLLAGADRIEGCLFGNGERTGNVDLITLALNLYTQGISPG
LDFSDIDEVIRCAEECNKISVHPRHPYAGDLVFTAFSGSHQDAIKKGFAQQKPDSIWEVP
YLPIDPADLGRSYDAIIRVNSQSGKGGVAYLLEQEYGLIIPRRLQIEFSKIIQKLTDETG
KEVTASTVYAIFKKEYLDQITPWKLIKHRIDGNPDSLENQKFNIKVELSYNNEIQIIEGT
GNGAISAFISSLNIPIRISDYHEHAIGTGTNTQAACYVELRVENSSTSFGVGIDKDIVTA
SFKAVLSALNRYQNKQK
NT seq
1674 nt
NT seq
+upstream
nt +downstream
nt
atgcttacaaatccatctaaaaaatatgtgccatttcgtccctttaaaaaggatttttca
gaaagaacatggcctagtaaaattattaccaaagctccaatatggatgacaactgattta
cgtgatggtaaccaatcattggtagatccaatgagtactcatcaaaaattgagatttttt
gatcagttaattaaaattggttttaaagagatcgaaataggatttccttctgcatcacaa
atagaatttgattttatacgtaaattaattgaagaagaaagaatacctgatgatgtaaca
attatacttttaactcaagcacgtgaagatttaatcaaaaggactgttgaatcagctatt
ggtgcaaaaaatattatgatccatatgtataattcttgcgccccatcttttagaaagata
gtttttcgtatgactcgtgatgaaataaaaaatttagctattcatggaacggaattagta
agaaattatactagcttatatccaaagacagaatggcgttttgaatattcaccagaagta
tttagtacaacagaattagattttgcattagacatatctaatgcagtcatagatacatgg
aaacctatatcaactaataaaatggttttaaatttaccatctactatagaatctaatact
ccaaatatatatgctgatcaaattgaatggatgcataataatttatcacatagggataaa
attttattaagtgtacatcctcataatgatagaggaacatcagtagctgctgctgaacta
tctcttttagcaggggcagatagaatagaaggctgtttatttggtaatggtgaaagaact
ggtaatgtagatttaattactttagcattaaatttatatactcaaggtatttcaccagga
ttagacttttctgatatagatgaagttatacgttgtgcagaagaatgtaataaaatttca
gtacatcctagacatccttatgctggtgatttagtatttactgctttttctggatcacat
caagatgctattaaaaaaggatttgcacaacaaaaacctgactctatttgggaagtacct
tatttaccaattgatcctgcagatttaggaagaagctatgatgcaattattagagtaaat
agtcaatctggtaaaggaggggtagcttatttattagagcaagaatatggattaattatt
cctagaagattacaaatagaattcagcaaaataatacaaaaattaacagatgaaactggc
aaagaagttacagcatcaacagtatatgcaatttttaaaaaagaatatttagatcaaatt
actccttggaaattaataaaacatcgtatagatggaaatccagatagtcttgaaaatcaa
aaatttaatatcaaagtagaactttcttataataatgaaattcaaataattgaaggaact
ggtaatggtgctatctctgcatttatttcttctttaaatataccaattagaatttctgat
tatcatgagcatgcaataggtactggtactaatacacaagcagcatgttatgtagagttg
agagttgaaaactcaagtacaagttttggtgtaggtatagataaagatattgtaacagca
tcttttaaagcagtattaagtgctttaaatagatatcaaaataaacaaaaataa
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