Lysobacter antibioticus 76: LA76x_0319
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Entry
LA76x_0319 CDS
T04154
Symbol
dhbF
Name
(GenBank) dimodular nonribosomal peptide synthase
KO
K02364
L-serine---[L-seryl-carrier protein] ligase [EC:
6.3.2.14
6.2.1.72
]
Organism
lab
Lysobacter antibioticus 76
Pathway
lab01053
Biosynthesis of siderophore group nonribosomal peptides
lab01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
lab00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01053 Biosynthesis of siderophore group nonribosomal peptides
LA76x_0319 (dhbF)
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins [BR:
lab01008
]
LA76x_0319 (dhbF)
Enzymes [BR:
lab01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.72 L-serine---[L-seryl-carrier protein] ligase
LA76x_0319 (dhbF)
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.14 enterobactin synthase
LA76x_0319 (dhbF)
Polyketide biosynthesis proteins [BR:
lab01008
]
Nonribosomal peptide synthetase (NRPS)
Iterative NRPS
Enterobactin synthetase
LA76x_0319 (dhbF)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AMP-binding
Condensation
Thioesterase
PP-binding
AMP-binding_C
Abhydrolase_1
Motif
Other DBs
NCBI-ProteinID:
ALN78481
UniProt:
A0A0S2F4Y1
LinkDB
All DBs
Position
complement(362196..366209)
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AA seq
1337 aa
AA seq
DB search
MRAMNESHCLALPLTTAQRGLWVGQKIASAEASMNIAEAVEICGPVDAELFLRALRQFTR
EADATRVRIVEHGGLPRQIVREEYESDFPYFDLSLEADPRAAAERWMQAELAKPVDFVHD
PLWVGALFKLADDRYCWYQRAHHTIYDGYSGGMTVRRVSELYSAYVEGREPEPCGYGSLA
ALVESEAAYRGSERFQRDRAFWREQLAALPEAVTLARRRVRNNGGLRRARGLLDDAARTR
LVEIARDCAVSLPQVLIALIAAYYHRATGAHDLVFGMPVTGRVNHALRSTPGMVANVVAI
RLAMSPQMTMPELFAQVSRVVRQALRHQQYRYEDLRRDLGLVNPDQHLAWLGINIEPFDY
GSFGGHRATGHNLHNGSAEDLTVFVYDRDDGEGLSFDLDANPTLYPAAELDEHRRRLMRL
IESVSADPSLSLGAIDVLGEQERERLLRGWNDTDAPLPDSTALDQFEQQAARTPDAVAVI
AGDTVLSYRELDESSTRLAHRLIAKGVRPGDIVAIALPRDQVLIAALLAVWKAGAAYLPL
DPEAPAERIALTLDDAAPSLLLTTANFAEAFAGRTLPLLFAHEQDEAYEIDVDAALPRAR
FDATAYLIYTSGSTGRPKGVQVTQRNLGNFLLATQRLFAPTAADRFLAQTTVAFDIACFE
LFLPLSVGARIVVTTAEVVRNPLALARLIAEHALNFVQATPSLWRMLLANPELRLDGVHA
LSTGEALPPELAQRLVAAAARVTNLYGPTETTVWASAIEITAADLADGAPPPIGKPLSNT
RAYVLDTTLSPVPTGSVGELYIGGACVAKGYLGRDDLTAERFIADPFADPLSAADARLYR
TGDLARWRDDGIIEYLGRADQQVKIRGHRVELGEIETHLRAEETVAEVAVALHTDAAGHA
LLAAYLVPATGLSLDSDGLRRRLAAKLPDHMVPSVYVELAALPLTPSGKLDRKALAPPER
NRQAVYAAPRSEIERKLVALWQQIFGLERVGIHDNFFELGGDSLTAAELVAAFPQHFGSE
LSLGALFDGSTIAGLAAYLEHSGGENDPLGALLSLRPTDRERPLFCIHPVTGFSWSYAGM
LRHLDETLPVYALQSRGLRGGGALPGSIEEIAADYIAQMRRIQPQGPYRLLGWSLGGLIG
HAIAAQLQQVGERIELLAMMDSYPFVADAHDAQSEAQQAVAVLKFLGFHHRTRDNPPQDM
RSLADLLCREYEVFSIPLVQEIMKADARLIENVTAVTRNNLMLARRYRPAPIETDVVFFN
AGLKEHVDLDGLLHYHAAAWQPFIGGRIEIHDVDCHHQSMLEPRAAAHIGRVLRERLDSP
PLPSPPPTPAALAVAYS
NT seq
4014 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgccatgaatgaatcccactgccttgccctgcccctgaccaccgcccagcgcgga
ctgtgggtcgggcagaagatcgcctcggccgaagcctccatgaacatcgccgaagccgtg
gagatttgcggcccggtcgatgccgagctgttcctgcgcgcactgcgccaattcacccgc
gaagccgatgccacccgcgtgcgcatcgtcgaacacggcggcctgccgcgccagatcgtg
cgcgaggaatacgaaagcgacttcccttatttcgacctcagcctggaagccgacccgcgc
gcggccgcggaacgctggatgcaggccgaactcgccaagccggtcgacttcgtccacgac
ccgctctgggtcggcgcgctgttcaagctcgccgacgaccgctattgctggtaccagcgc
gcccatcacacgatctacgacggctacagcggcggcatgaccgtacgccgcgtcagcgag
ttgtacagcgcctatgtcgaaggccgcgagcccgagccctgcggctacggttcgctggcg
gcgctggtcgaaagcgaagccgcctaccgcggctccgaacgtttccagcgcgaccgcgcg
ttctggcgcgagcaactggcggccctgcccgaggcggtgaccctggcgcgccgacgcgtg
cgcaacaacggcggcctgcgccgcgcgcgcggcctgctcgacgacgcggcgcgcacgcgt
ctggtcgagatcgcacgcgattgcgccgtgagcctgccgcaggtgctgatcgcgctgatc
gccgcctactaccaccgcgccaccggcgctcacgacctggtgttcggcatgccggtcacc
ggccgcgtcaatcacgccctgcgcagtacgccgggcatggtcgccaacgtggtcgcgatc
cgtttggcgatgagcccgcagatgaccatgccggaattgttcgcgcaggtctcgcgcgtg
gtcaggcaggcgttgcgccaccagcagtatcgctacgaagacctgcgccgcgacctcggc
ctggtcaaccccgaccagcacctggcctggctcggcatcaacatcgagcccttcgactac
ggcagcttcggcggccatcgtgcgaccgggcataacctgcacaacggctcggccgaagac
ttgaccgtgttcgtctacgaccgcgacgacggcgaaggcctgagcttcgacctcgacgcc
aacccgaccctgtacccggccgcagaactcgacgaacaccggcgccgcctgatgcgcttg
atcgaatcggtgtcggccgatccgtccctgagcctcggcgccatcgacgtgctcggcgag
caagagcgcgaacgcctgctgcggggctggaacgacaccgacgcaccgctgccggacagc
accgcgctcgaccagttcgaacagcaggccgcgcgcaccccggatgcggtcgcggtgatc
gccggcgacacagtgctgagctatcgcgaactcgacgagagcagcacccgcctggcccac
cgcttgatcgcgaagggcgtacgccccggcgacatcgtcgccatcgccctgccgcgcgac
caagtgctgatcgcggccctgctcgcggtgtggaaggccggtgcggcctatctgccgctg
gacccggaagcgccggccgagcgcatcgccctgaccctcgacgatgccgcgcccagcctg
ttgctgaccactgcgaacttcgccgaggccttcgccggccgcaccctgccattgctgttc
gcccacgaacaggacgaggcctacgagatcgacgtcgacgccgccctgccgcgcgcgcgc
ttcgacgccaccgcctacctgatctacacctcgggctcgaccggccggcccaagggcgtg
caagtcactcagcgcaatctcggcaatttcctgctcgcgacccagcgcctgttcgcgccg
accgcggccgatcgattcctggcccagaccacggtcgctttcgacatcgcctgcttcgag
ctgttcctgccgctcagcgtcggcgcgcgcatcgtcgtgaccaccgccgaggtggtgcgc
aatccgctcgccctggcccgcctgatcgccgagcacgcgctcaatttcgtccaggccaca
ccgtcgctgtggcgcatgctgctggccaatccggaactgcgcctggacggtgtgcacgcg
ctgtcgaccggcgaagccttgccgccggaactcgcccagcgcctggtcgccgcggccgcg
cgcgtgaccaatctgtacgggccgaccgaaaccacggtgtgggccagcgcgatcgagatc
accgcggccgacctcgccgacggcgcgccgccgccgatcggcaagccgctgtcgaacacc
cgcgcctacgtgctcgacaccacgctgagcccggtgccgaccggcagcgtcggcgagctc
tacatcggcggcgcctgcgtcgccaagggttatctggggcgcgacgacctcaccgccgag
cgcttcatcgccgatcctttcgccgacccgctcagcgccgccgacgcacgtctgtatcgc
accggcgacctcgcgcgctggcgcgacgacggcatcatcgaatacctcggccgcgccgac
cagcaggtcaagatccgcggccaccgggtcgaactgggcgagatcgaaacccatctgcgc
gccgaggaaaccgtggccgaggtcgcggtcgccctgcacaccgacgccgcgggacacgcg
ctgctcgccgcctatctggtgccggcgaccggcctgagcctcgacagcgacggcctgcgc
cgtcgtctcgccgccaagctgcccgaccacatggtgcctagcgtctacgtcgaactggcg
gcgctgccgctgacgccgagcggaaaactcgaccgcaaggcgctggcgccgccggagcgc
aaccgccaggccgtctatgccgcgccgcgcagcgagatcgaacgcaagttggtggcgctg
tggcagcagatcttcggcctcgaacgcgtcggcatccacgacaacttcttcgagctcggc
ggcgattcgctgaccgccgccgaactggtcgccgccttcccgcagcatttcggcagcgag
ctgtcgctgggcgccctgttcgacggctcgaccatcgccggcctggccgcgtatctcgag
cacagcggcggcgagaacgatccgctcggcgcgctgctgtcgctgcgcccgaccgatcgc
gagcggccgctgttctgcatccacccggtaaccggcttcagctggtcctacgccggcatg
ttgcgccacctcgacgagaccctgccggtgtacgccctgcagtcgcgcggcctgcgcggc
ggcggcgccctgcccggcagcatcgaggagatcgccgccgactacatcgcgcagatgcgc
cggatccagccgcaggggccgtaccgtttactcggctggtcgctcggcggcctgatcggg
catgccatcgccgcgcagttgcagcaggtcggcgaacgcatcgaactgctggcgatgatg
gattcgtatccgttcgtggccgacgcccacgacgcccagagcgaagcccaacaggccgtg
gccgtgctcaagttcctcggcttccaccaccgcacccgcgacaacccgccgcaggacatg
cgcagcctggccgatctgctgtgccgcgagtacgaggtgttctcgattccgctggtgcag
gaaatcatgaaggccgatgcgcgcctgatcgagaacgtcaccgcggtgacccgcaacaat
ctgatgctggcgcggcgttaccggccggcgccgatcgagaccgacgtggtgttcttcaac
gccggcctcaaggagcacgtcgatctggacggcctgctgcattaccacgccgcggcctgg
cagcccttcatcggcgggcgcatcgagatccacgacgtcgactgccatcaccagtcgatg
ctcgaaccgcgcgcggccgcccacatcggccgcgtgctgcgcgagcggctggactcgccg
cctctgccttccccgccaccgacgccggccgcgctcgcggtcgcgtactcgtaa
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