Lysobacter antibioticus 76: LA76x_1170
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Entry
LA76x_1170 CDS
T04154
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lab
Lysobacter antibioticus 76
Pathway
lab00300
Lysine biosynthesis
lab00550
Peptidoglycan biosynthesis
lab01100
Metabolic pathways
lab01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lab00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LA76x_1170
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LA76x_1170
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LA76x_1170
Enzymes [BR:
lab01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LA76x_1170
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Thiopep_pre
Motif
Other DBs
NCBI-ProteinID:
ALN79329
UniProt:
A0A0S2F785
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All DBs
Position
1346931..1348322
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AA seq
463 aa
AA seq
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MKSLLLSEIARMTGGRLRGADAAIDLVVTDTRALPETGAALFVALKGERFDGHDHVAKLA
GSAVVGALVAREIDARVAQVVVADSERALADLAAAVQAQRSGSTVVAITGSNGKTSVKTL
TAAILERAGRTYATPGNRNNEIGLPLAVLDAPEDAQFAIYEMGAGKPGDIAYLVRVARPQ
VALVNNIAPAHLERMGSLLGIADTKAAIYDALPADGVAVINADDAFAPYFGERAAGRRVI
RFGLDASAEVTAHDVRLGTEGSTFVLVAPQGRAEIALQLVGRHNVRNALAAASLALAAGA
GFDAVVAGLNAARPVEGRLITHRLDNGAVLIDDSYNANPGSTAAAIDALAEIGGENWLVL
GDMREIGNDEIAMHVEIGRRAKASGIRRLYALGALSSAAAQAFGEGGSVHESHAALAQTL
AADLRDGVRVLVKGSHSSAMDRIVTALLSAQKPEQGKGTSHVA
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atgaagagcctgctgctgtccgaaatcgcgcgcatgaccggcggccgcctgcgcggcgcc
gatgcggcgatcgacctggtcgtcaccgacacccgcgcgctgcccgagacaggcgcggcg
ctgtttgtcgcgctcaagggcgaacgcttcgacggccacgaccatgtcgccaagctcgcc
ggcagcgcggtcgtcggcgctctggtcgcgcgcgagatcgatgcccgggtcgcccaggtg
gtggtcgccgacagcgagcgcgcgctcgccgacctcgccgccgcagtgcaggcgcagcgc
agcggcagcaccgtggtcgctatcaccggcagcaacggcaagaccagcgtcaagaccctg
accgcggcgatcctcgaacgcgccggccgtacctatgcgacgccgggcaaccgcaacaac
gagatcggcctgccgctggcggtgctcgacgcaccggaagacgcgcagttcgcgatctac
gaaatgggcgccggcaagcccggcgacatcgcttacctggtgcgcgtggcgcgcccgcaa
gtggccctggtcaacaacatcgccccggcgcatctggaacgcatgggcagcctgctcggc
atcgccgacaccaaggcggcgatctacgacgctttgccggcggacggcgtggcggtgatc
aatgccgacgacgccttcgctccgtacttcggcgaacgtgcagccgggcgccgggtgatc
cgcttcggcctggacgccagcgccgaggtcaccgcgcacgacgtccgcctcggcaccgaa
ggctcgaccttcgtactcgtcgcgccgcaggggcgggcggagatcgcgctgcagttggtc
gggcgccacaacgtgcgcaacgcgctcgccgcggcctcgctggcgctcgctgccggcgcc
ggcttcgacgcggtcgttgccggcctgaacgccgcgcgcccggtcgagggacgcctgatc
acccaccgcctcgacaacggcgcggtgttgatcgacgacagctacaacgccaaccccggc
tcgaccgcggcggcgatcgatgcgctggccgagatcggcggcgagaactggctggtgctc
ggcgacatgcgcgagatcggcaacgacgagatcgcgatgcacgtcgagatcggccgccgc
gccaaggcttccggcatccgccgtctgtacgcgctcggcgcgctcagcagcgcagcggcc
caggctttcggcgagggcggcagcgtgcatgaaagccatgccgcgctcgcgcagacgctg
gccgccgacttgcgcgacggcgtacgggtgttggtcaaaggttcgcacagcagtgcgatg
gatcggatcgtgacggcgttgctgtccgcgcagaagcccgaacaggggaaggggacgtcg
catgttgcttga
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