Lysobacter antibioticus 76: LA76x_4254
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Entry
LA76x_4254 CDS
T04154
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
lab
Lysobacter antibioticus 76
Pathway
lab00290
Valine, leucine and isoleucine biosynthesis
lab00620
Pyruvate metabolism
lab01100
Metabolic pathways
lab01110
Biosynthesis of secondary metabolites
lab01210
2-Oxocarboxylic acid metabolism
lab01230
Biosynthesis of amino acids
Module
lab_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
lab00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
LA76x_4254 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LA76x_4254 (leuA)
Enzymes [BR:
lab01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
LA76x_4254 (leuA)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ALN82365
UniProt:
A0A0S2FFR7
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Position
4862418..4863899
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AA seq
493 aa
AA seq
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MTASQKLRFAHALSELGVDVIEAGFPASSEADLEGTRAIVREVRGSTVATLARCHPGDIE
ACARALEGAAKPRIHVFISTSPLHRQHKLNLDKEQVIERAIAAVEQARRYVDDVEFSAED
ALRTEHDYLAQICSAAVAAGARTLNIPDTVGYTTPSEIRSLFEYLRANVRDADRAVFSAH
CHNDLGLAVANSLAAIEGGARQVECTINGIGERAGNCALEELVMALRVRNAYYNVGTRID
TRRLVPTSRLLSRITGMVVQRNKAIVGQNAFAHESGIHQHGMLKHRGTYEIMHPEDVGWA
QSQMVMGRHSGRAALSDRLQTLGFTLDEARLNAVFAGFKALAEKKREVFDADLESLVLGA
DAKAARGHRLVRAHVSTGVADGSLPTASVQLLDPDGAAVSEAAIGDGPVHALFAALARAT
GVALRIDSYNVSSVTTGDDAQGQASVTARIDGIEMTGSGTSTDIIEASALAWLDVANRIR
RTQQAPQRLTATA
NT seq
1482 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcctcgcagaagctgcgcttcgcccacgccctgtccgagctcggcgtcgacgtc
atcgaagccggcttcccggccagctccgaagccgatctggaaggcacccgcgcgatcgtg
cgcgaggtacgcggctcgaccgtcgcgaccctggcgcgctgccaccccggcgacatcgaa
gcctgtgcgcgcgcgctcgaaggcgccgccaagccgcgcatccatgtcttcatctcgacc
agcccgttgcaccgccagcacaagctcaacctggacaaggagcaggtgatcgaacgcgcg
atcgccgcggtcgaacaggcgcgtcgatacgtcgacgacgtcgaattctcggccgaggac
gcgctgcgcaccgagcacgactatctggcgcagatctgcagcgccgcggtcgccgccggc
gcgcgcaccttgaatatccccgacaccgtcggctacaccacgccgagcgaaatccgcagc
ctgttcgagtacctgcgcgcgaacgtgcgcgacgccgaccgcgccgtgttcagcgcccac
tgccacaacgacctgggcctggccgtggccaacagcctggccgcgatcgaaggcggcgcg
cgccaggtcgagtgcaccatcaacggcatcggcgaacgcgccggcaactgcgccctggaa
gagctggtgatggcgctgcgcgtgcgcaacgcttattacaacgtcggcacgcgcatcgac
acgcgccggctggtgccgacctcgcgcctgctgtcgcgcatcaccggcatggtggtccag
cgcaacaaggccatcgtcggccagaacgccttcgcccacgagtccggcatccaccagcac
ggcatgctcaagcaccggggcacctacgagatcatgcatccggaagacgtgggctgggcg
cagtcgcagatggtgatgggccgccacagcggccgcgccgcattgagcgaccgcctgcag
accctgggtttcaccctggacgaggcgcgcttgaacgcggtgttcgccggcttcaaagcc
ttggccgagaaaaagcgcgaagtgttcgacgccgacctggaatcgctggtgctcggcgcc
gacgccaaagccgcccgcggccatcgcctggtacgcgcgcacgtcagcaccggcgtcgcc
gacggcagcctgccgaccgcgagcgtgcagttgctcgatcccgacggcgccgcggtcagc
gaggcggcgatcggcgacggcccggtgcacgccttgttcgccgcgctcgcgcgcgcgacc
ggcgtagccttgcgcatcgacagctacaacgtgtcgagcgtgaccaccggcgacgacgcc
cagggccaggccagcgtgaccgcgcgcatcgacggcatcgagatgaccggctcgggcacc
agcaccgacatcatcgaggccagcgccctggcctggctcgacgtcgccaaccgcatccgt
cgcacccagcaggcgccgcagcggctgacggccacggcatga
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