Lactobacillus acidophilus NCFM: LBA0795
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Entry
LBA0795 CDS
T00231
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
lac
Lactobacillus acidophilus NCFM
Pathway
lac00790
Folate biosynthesis
lac01100
Metabolic pathways
lac01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
lac00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LBA0795 (folC)
Enzymes [BR:
lac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LBA0795 (folC)
6.3.2.17 tetrahydrofolate synthase
LBA0795 (folC)
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Gene cluster
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
ALIX_LYPXL_bnd
Motif
Other DBs
NCBI-ProteinID:
AAV42660
UniProt:
Q5FKW4
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All DBs
Position
778896..780167
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AA seq
423 aa
AA seq
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MKFTSAQKIIDYLYSLPHLHPKNDLSFIKRLLKKLGNPQNQVKTIHITGTNGKGSTSYYL
SNLLKKAGQKTGLFVSPYVYRFNERIQLDNQDISDQDLIVVANIVQKAYEELQEEDSAFS
LVTFEYEVALAFVYFAQKKCDYAVIEVGIGGEHDKTNVIMPEASIITTIGLDHEQIIGPT
IQDIAREKSGVIKHNRPVILGNIPKNVLPILEQKAKIEDAPIYLLGKDFNVSIDQKIHYI
DSQYKLNFVLRAQVEAYDIAVAFKTFSLLNLKLSDEDIENAIDQTIIPGRYHILEQKPLV
ILDGAHNIQAMTNLLNTVHQLAQKRGGHVHALITMMKDKDLEQVFSLFNKDDDVLLTTLS
YARTAKKNDFPIDVERRYNYDRDYRSGFTKLKNKMADNDVLLVTGSFYLVSAILNWKRRK
NAR
NT seq
1272 nt
NT seq
+upstream
nt +downstream
nt
ttgaagtttactagtgctcaaaaaataattgattatctgtattctttgccacatttacat
cctaaaaatgatctatcctttatcaaaagattgttaaaaaaattaggtaatccgcaaaat
caggtaaaaacaattcatattacgggtacaaatggtaaaggttcaacttcctactattta
tcaaatctactaaaaaaggccggtcaaaagactggcctttttgtatcaccttatgtctat
cgatttaatgagcgaattcagttagataatcaagacattagtgatcaagatttgattgta
gtagctaacattgttcaaaaagcttatgaagaactgcaagaagaagattcagccttttct
ttagttacttttgaatatgaagttgctttagcttttgtatactttgcccaaaaaaagtgt
gattatgctgtaattgaagttggtattggtggtgagcatgataaaactaatgtaattatg
cccgaggcaagtattattacaacgattggtttagatcatgaacaaattattggacctaca
atccaagatattgcacgtgaaaaaagtggagttattaagcataatcgacctgtaatatta
gggaatattcctaaaaatgttttgccaattttagaacaaaaagccaagatagaagatgcg
cctatctatttattaggtaaagatttcaatgtgagcattgatcagaaaatccattatatc
gattcacagtataagttgaattttgtattacgtgcgcaagttgaagcatatgatattgca
gttgcctttaaaactttttcattattgaatttgaagttaagtgatgaagacattgaaaat
gcaattgatcaaacaattattccgggacgttatcatattttggagcaaaaaccattggtt
attttagatggtgcgcataatattcaggcgatgaccaatctgcttaatacagttcatcag
cttgctcaaaagcgtggtggacacgtacatgctctaattacaatgatgaaagataaagat
ttggagcaagtatttagtttattcaataaagacgatgatgtgttacttaccacgttgtca
tatgcgcgaactgcgaaaaaaaatgattttccaattgacgtggaaagaagatataattat
gacagagattatcggtctgggtttactaaattgaaaaataaaatggcagataatgatgta
ttacttgtcacaggttctttttatttagtaagtgcaattttaaattggaagaggcgaaag
aatgcgcgttaa
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