Lactobacillus acidophilus NCFM: LBA1556
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Entry
LBA1556 CDS
T00231
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
lac
Lactobacillus acidophilus NCFM
Pathway
lac00230
Purine metabolism
lac01100
Metabolic pathways
lac01110
Biosynthesis of secondary metabolites
Module
lac_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lac00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
LBA1556 (purL)
Enzymes [BR:
lac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
LBA1556 (purL)
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GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AAV43373
UniProt:
Q5FIV1
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All DBs
Position
complement(1549131..1551359)
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AA seq
742 aa
AA seq
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MKQAMTPEEIKEKKPYLDWSLSEHEYDYICDHLLHRLPNYTEIGLFSAMWSEHCSYKKSK
PVLKLFPTKGKRVVQGPGEGAGVVDIDDGQAVVFKAESHNHPTTVEPYQGAATGVGGILR
DVFSMGARPVAILDSLHFGELKDNPTMRYKMEETIKGVGDYGNCMGIPNLGGETTFDPCY
NGNILLNAMNVGIMDIKDMEHGDATGVGNAVMYVGAKTGRDGIHGATFASADFSEEHATQ
RSAVQVGDPFMEKLLMEACLELILHHREWLVGIQDMGAAGIVSSSAEMATEGKSGMDLNL
NLVPQREPNMSAYEIMLSESQERMLLCVKKGHEEDVKKIFDEYNLDAVTIGRITDDGRYV
LHHDDQVVCDIPVVTLTEKVLEEKSEEKKPQRIIDVEQSENWQPEIEDAGQTLRALLNQP
TIANDQFVTQQYDSQVRTDTIVGPGSDSGILRVRHTKKAIAMTTDTNGRFVYLDPKVGGQ
RTVLESATNIVASGALPLAITDCLNYGDPNDPEIFWELHQSCQGIADACEILETPVVSGN
VSLYNENNGKAIYPSPMIGMVGLIKNYDHVIPMHMQTAGDKIYLVGKTDDDFAGSELQKM
MTGKISGLPHAPNLPGIKDYLYKLQKLMAEGLVQSAHDLSEGGLGVSLAESVFDTDLGVN
VKLDFNKNLLFSETPGRLIVSVAPENAAKFEQEMGDAVSEIGQVTDDKQLNISLTNDQVN
EDVAKLQKIWKECIPCLMKSKA
NT seq
2229 nt
NT seq
+upstream
nt +downstream
nt
atgaaacaagcgatgacaccagaagaaatcaaagaaaagaagccttaccttgattggagc
ttatcagaacatgaatatgactatatttgtgatcatttgcttcatcgcttgcctaactat
actgaaatcggtttgttctccgcaatgtggagtgaacactgttcttacaagaaatccaag
ccagtactaaagcttttcccaactaagggtaaacgtgttgtccaaggcccaggtgaaggt
gccggcgtagttgatattgatgatggacaagcagttgtgttcaaagctgaaagtcacaac
cacccaactacagttgaaccttaccaaggtgccgcaactggtgttggcggtattttaaga
gatgttttcagtatgggagctcgtccagtcgcaatccttgattcgcttcactttggtgaa
ttaaaggataatccaacaatgcgttacaagatggaagaaactatcaagggcgtgggcgac
tatggcaactgcatgggaatccctaacttaggtggtgaaaccacctttgatccttgctat
aacggcaacattttgcttaacgcaatgaacgtcggcattatggatatcaaggatatggaa
catggggatgccacaggtgtcggcaatgcagtaatgtatgtcggtgctaaaactggtcgt
gacggtatccacggtgcaacttttgcttcagccgacttttctgaagaacatgctactcaa
cgttcagcggttcaagttggtgatccatttatggaaaagcttttgatggaagcctgcctg
gaattgattttgcatcaccgcgaatggctcgtcggtattcaagacatgggtgcagctgga
atcgtatcttcaagtgctgaaatggccactgaaggtaaatctggcatggatcttaatttg
aacttggttcctcaacgtgaacctaatatgtcagcttacgagattatgcttagcgaatcg
caagaaagaatgcttctttgcgtgaagaagggtcacgaagaagacgttaaaaagattttt
gatgaatataatcttgatgcagtgactattggtcgaattactgatgatggcagatatgtt
cttcatcatgatgatcaagtagtttgcgacattccagttgtaactttgactgaaaaggtt
cttgaagaaaaaagcgaagagaaaaagccacaaagaattattgatgtagaacaaagcgaa
aactggcaacctgagattgaagatgcaggtcaaaccttaagagctcttttgaatcaacca
actattgctaatgatcaatttgtaacacaacaatatgactcacaggttcgcacagatact
attgttggtcctggttcagatagcgggattctgcgtgttcgccatactaagaaggcaatc
gccatgacaactgataccaatggtcgttttgtctatcttgatcctaaagttggcggacaa
agaacagtccttgaaagtgccacaaacattgtagctagtggtgctttgcctttagctatt
accgactgccttaactatggtgatcctaatgatccagaaatcttctgggaattacaccaa
tcttgccaaggaattgccgatgcatgtgagatcttagaaacaccagttgtttcaggcaat
gtttctctttataacgaaaacaacggtaaggcaatttatccatcgccaatgatcggtatg
gtgggattgatcaaaaactatgatcatgtcattccaatgcatatgcaaacagcaggcgac
aagatttatctcgttggtaaaacagatgatgattttgctggttcagaattgcaaaagatg
atgacaggtaaaattagcggcttgccacatgcaccaaatttgccaggaatcaaagactac
ctatataaattgcaaaaattaatggcagaaggacttgtccaaagtgctcatgatttaagc
gaaggtggcttaggcgtatccttagctgaaagtgtatttgatactgatcttggcgtaaac
gtaaaactcgattttaataaaaatcttttgttcagtgaaactccaggacgcttgatcgtt
tccgtcgctcctgaaaatgcggcaaagtttgaacaagaaatgggcgatgcagttagcgaa
attggtcaagttacagatgacaagcaattaaatatttctcttacaaatgatcaagtaaat
gaagatgttgcgaaattgcaaaagatttggaaggagtgcatcccttgtttaatgaaatca
aaagcctaa
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