Lactococcus sp. NH2-7C: QJV49_09165
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Entry
QJV49_09165 CDS
T10489
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lacn Lactococcus sp. NH2-7C
Pathway
lacn00300
Lysine biosynthesis
lacn00550
Peptidoglycan biosynthesis
lacn01100
Metabolic pathways
lacn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lacn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
QJV49_09165 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
QJV49_09165 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
QJV49_09165 (murF)
Enzymes [BR:
lacn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
QJV49_09165 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF6585
Motif
Other DBs
NCBI-ProteinID:
WGV29694
UniProt:
A0AA49EV68
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Position
1807821..1809143
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AA seq
440 aa
AA seq
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MKLTIHEIAQVVGAKNDWSQLADLSVNKIEFDSRLIEKGDIFLPLKGARDGHDFIKIAFD
NGAIISFSEKEVEQAHLLVDDNLLAFQKLAKYYLEKTKVPVIAVTGSNGKTTTKDMIAAV
LSKKFKTYKTQGNHNNEIGLPYTILHMPDDTEKLVLEMGMDHPGDIDFLSELAQPELAVI
TLIGEAHLEFMGSRENIAKGKMGITAGLHGELIAPADPIINAFIPDNQKISRFGLPGEDL
FITKLVEHKEKLTFETNFLDESITIPVPGKYNATNAMLAAYVGLHYGLSEAEIKKALKEV
ELTRNRTEWKKAKNGADLLSDVYNANPTAMRLILETFQAIPKNENGRKIAVLADMLELGP
SAAQLHKDILKSIDFDKIDKVYLYGEMMKNLAEISTDKAVSYFTDLDLLTESLSADLKPT
DQVLFKGSNSMKLSEVVEKL
NT seq
1323 nt
NT seq
+upstream
nt +downstream
nt
atgaaactcacaattcacgaaatcgcccaagtcgttggcgcaaaaaatgattggtcgcaa
ctggcagatttgtcagtcaataaaattgaatttgatagccgtttgattgaaaaaggggat
atctttttgccacttaagggggcacgagatggtcatgatttcatcaaaatcgcttttgat
aatggagcaataatcagcttttcagaaaaagaagtcgaacaagctcatctcttggttgac
gataatctgcttgctttccaaaaattggcaaaatattatcttgaaaagacaaaagttcca
gtcattgcggtgacaggttcaaatggaaaaacaacaactaaagacatgattgctgctgtt
ttgtctaagaaatttaaaacatacaaaacacaagggaatcacaataatgaaatcggctta
ccttacaccattttacatatgccggacgatactgaaaaattagttttggaaatgggaatg
gatcaccctggtgatattgattttttatcagaacttgctcagcctgaacttgctgtcatt
accttaattggtgaagcgcatcttgaatttatgggaagtcgtgaaaatattgctaaaggg
aaaatggggattacggctggtttgcatggtgagctaattgcccctgctgacccaattatt
aatgcttttatcccagacaatcaaaaaattagtcgctttggtttgcccggtgaagattta
tttattacaaaattagtcgaacataaagaaaaattaacttttgaaactaattttttagat
gaatcaattactattccagttcctggtaaatataacgctacgaatgctatgttagctgct
tacgttggcttacattatgggctgtcagaagccgaaattaaaaaagctttgaaagaagta
gagctgaccagaaatcggacagagtggaaaaaagcaaaaaatggtgctgaccttttgagt
gatgtttataatgccaatccgacagcaatgcgtttgattttggaaactttccaagctatt
cccaaaaatgagaatggtcgaaagattgcagttcttgctgatatgttagaacttggaccc
agtgcagctcaactccataaagatatattgaaatctatagatttcgacaaaattgataaa
gtttatctttatggtgaaatgatgaaaaatttggcagaaatttcgactgacaaagctgtc
agctattttacagacttagatttactgacagaaagtctgtcagcagatttgaaaccaact
gaccaagttttattcaaaggttcaaatagtatgaaactttcagaggttgttgaaaaatta
taa
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