Lacibacter sediminis: H4075_11915
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Entry
H4075_11915 CDS
T06746
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lacs
Lacibacter sediminis
Pathway
lacs00260
Glycine, serine and threonine metabolism
lacs00261
Monobactam biosynthesis
lacs00270
Cysteine and methionine metabolism
lacs00300
Lysine biosynthesis
lacs01100
Metabolic pathways
lacs01110
Biosynthesis of secondary metabolites
lacs01120
Microbial metabolism in diverse environments
lacs01230
Biosynthesis of amino acids
Module
lacs_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
lacs_M00527
Lysine biosynthesis, DAP aminotransferase pathway, aspartate => lysine
Brite
KEGG Orthology (KO) [BR:
lacs00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
H4075_11915 (thrA)
00270 Cysteine and methionine metabolism
H4075_11915 (thrA)
00300 Lysine biosynthesis
H4075_11915 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
H4075_11915 (thrA)
Enzymes [BR:
lacs01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
H4075_11915 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
H4075_11915 (thrA)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
ACT
ACT_7
NAD_binding_3
GDH2_N
RHH_8
Motif
Other DBs
NCBI-ProteinID:
QNA42803
UniProt:
A0A7G5XBF0
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All DBs
Position
2820101..2822542
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AA seq
813 aa
AA seq
DB search
MLVLKFGGTSMGSAEAIKQVVEIVKEKAKESSVILVVSAMSGTTDLLLNCGTKAANDDES
YKEILKQIETRHLDTVKSLIPVQQQSSVLSMVKKLCNEIEDICNGIYLLNESSLRTKDKL
VSYGELLSSTMINAAFNSNGTSAVWKDARELIRTNSNYSNAIVDFAITNQQIKDFVSSTS
QKIIVLPGFIASDADNITTTLGRGGSDYTAAILAAAVDASALEIWTDVSGMMTADPRWVP
NAKIIPSISYQEAMELSHFGAKVIYPPTIQPVLSKNIPVWVKNTFAAKDHGTVIENKSDS
TNIITGISSINSLALLSLEGSGMIGIPGFSSRLFAALANAQINVILITQGSSEHSICVGV
DVASAARAKEVVDKTFEYEIATDKVDPLQIEEKLSIVALVGDQMRHHTGISGRMFSALGR
NGINIRAIAQGSTERNISAVVATDDVRKAVNVLHEEFFETIQKQVNLFIVGTGNVGKRLL
AQLKQQQGFLEQHLRLHVNIVGLSNSRKMLINENGIDLNKWDELLQNGEVSNLDQFVQSI
IKRNLRNSVFVDVTANAVIADVYASLLEKSIAVVACNKVAASSKLNNYKKLKHLSTEFNA
PFLFETNVGAGLPIIGSLNDLMRSGDRVHRMEAVLSGTLNFVFNHYDGTRPFADVVKQAQ
DEGYTEPDPRLDLSGTDVMRKILILAREAGVQMEMEEITCNGFLPESCVKGSVADFYEAM
KKEEAHFKAIFDKAHAENCKLKFVASFNDGKASVGLQHIPPQHDLYHLYGKDNVVLFYTD
RYKEQPMVVKGAGAGAEVTASGVFADILRAAQK
NT seq
2442 nt
NT seq
+upstream
nt +downstream
nt
atgctggttttaaaatttggtggcacttcaatgggaagcgcagaggcaatcaaacaggtt
gttgagatagtaaaagaaaaagcaaaggaatcttctgtaatactggtggtgagtgcaatg
agtggcacaaccgatctcttgcttaactgcggcacaaaagctgcaaacgacgatgaatcg
tacaaggaaatcctcaagcaaattgaaacaagacaccttgatacggtaaagtcattgata
ccggtgcagcagcaaagcagcgtattgagtatggtaaagaaactttgcaatgaaattgaa
gacatctgcaacggtatttaccttttgaatgaatcttcactgcgtacaaaagataaactg
gtgagttatggcgaattgctttcgtcaaccatgatcaacgccgcatttaattcaaatggc
acaagtgctgtttggaaagatgcacgtgaactcatacgcaccaattcaaactacagcaat
gcaattgttgattttgcaattaccaatcagcagataaaagatttcgtcagcagcacatca
caaaagatcattgtgctgcctggttttattgccagcgatgcagacaatatcactacaaca
ttaggtcgtggtggttctgattacacagcagcaattcttgcagcagcagttgatgcaagt
gccctggaaatatggacagatgtaagcggtatgatgaccgcagacccccgctgggttcca
aatgcaaaaattattccttccatttcttaccaggaggcaatggagctttcacactttggt
gcaaaggtgatttatccgccaactattcaacccgtattatcgaagaatattccggtttgg
gtgaagaatacatttgcagcaaaagatcacggaactgtaattgaaaataaatctgattcg
accaatatcattaccggcatctccagtatcaattcattggctttgttaagtcttgaaggt
agtggcatgatcggcatacccggtttcagcagccgtttgtttgcggcattggcaaatgcg
cagatcaatgttattctcattacacaaggctcaagtgaacactcaatttgcgtgggtgtg
gatgttgcttctgctgcaagagcaaaagaagtagttgataaaacatttgaatacgaaatt
gcaactgataaagttgatccgttacagatcgaagaaaaattatccattgttgcattggtg
ggagatcagatgcgtcaccacaccggtatcagcggaagaatgttttctgcattaggtcgc
aatggtatcaacattcgtgcaattgcacaaggttcaactgaacgtaatatttctgcagta
gttgcaaccgacgatgtacgcaaagctgtgaacgttttacatgaagagttttttgaaaca
attcagaaacaggtaaaccttttcattgttggcacaggtaatgtaggcaaaagattattg
gcacaattaaaacaacagcaaggatttcttgaacagcatttgcgtttgcatgtgaatatt
gttgggttgagtaacagtcgtaaaatgcttatcaacgaaaatggaatcgatctcaataaa
tgggatgagctgttgcaaaatggcgaagtttcaaatcttgatcagtttgtacaatccatc
atcaaacgtaacctgcgtaattctgtttttgttgatgttacggccaatgcagttattgct
gatgtgtatgcatccttacttgaaaagagtatagcagttgttgcatgtaataaagtggca
gcatcatccaaactcaacaattataaaaagctgaaacatctttcaacagaattcaatgca
ccgtttttgtttgaaacaaatgttggtgccgggttacccattattggttcgttgaacgat
ctgatgcgcagcggggacagagtgcacagaatggaagctgtattaagtggcacactcaat
tttgtatttaatcattacgacggtacaagaccttttgcagatgtagtaaagcaggcacag
gatgaaggttacactgaacccgatccacgtttggatctgagtggtactgatgtaatgcgt
aaaatattgattcttgcacgtgaagcaggcgtgcaaatggaaatggaagaaattacatgc
aatggctttttaccggaaagttgtgtaaaaggaagcgttgctgatttttacgaagcaatg
aaaaaagaagaagcacattttaaagccatcttcgataaagcacatgcagagaattgcaaa
ttgaaatttgttgcaagttttaacgatggtaaagcaagtgtaggtttgcagcatatacca
cctcagcatgatctctatcatttgtatgggaaagataatgtagttcttttctacaccgat
cgttacaaagaacaaccgatggtggtgaaaggtgcaggtgcaggcgcagaagtaacagca
agtggtgtgtttgcagatattttaagagccgctcaaaaataa
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