Lactobacillus acidophilus La-14: LA14_0259
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Entry
LA14_0259 CDS
T02647
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lad
Lactobacillus acidophilus La-14
Pathway
lad00300
Lysine biosynthesis
lad00550
Peptidoglycan biosynthesis
lad01100
Metabolic pathways
lad01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lad00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LA14_0259
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LA14_0259
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LA14_0259
Enzymes [BR:
lad01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LA14_0259
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RecA-like_ORC2
Motif
Other DBs
NCBI-ProteinID:
AGK93485
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Position
256417..257784
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AA seq
455 aa
AA seq
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MKMQMAEIAKALDKTCEGDDKTVITSVAFDSRKITNGGLFVPLEGERDGHDFVAGAISNG
ASATLWKKGHPNKPEGIAVIEVDDPLAAMQTLARYYLRKVNPTVVGITGSNGKTTTKDMI
AAVLSKRFNVHKTQANFNNEIGVPMTVLEMKPNTEILVLEMGMDRPGQLHHLSELTRPDV
AVITMIGEAHIEFFGSRDKIADAKMEITDFLREDGEFIYNGDEPLLQERAKKLDQAKATF
GFEDDDTVHATGFKSYMHHATFTINDSEQKFSIPMIGKHNVSNAMAAISVGRHFGESDEE
IASSLSNFKPTANRMEWEKGDVGEAIMSDIYNSNPTAVRAVITSFGQVEVKDGGRRIAVL
GDMLELGENSPKLHAELSDTLDPQIINEVYLYGPEMKNLYDALQGKYESEHLHYYTKDQM
DRMIDDLKNDIKSDDIVVLKGSHGMHLENVLARLR
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaaatggctgaaattgccaaagctttagataagacttgtgaaggtgacgat
aaaacagttattacttctgttgcctttgactccagaaagatcacaaatggtggattattt
gtaccacttgaaggtgaacgtgatggacatgattttgtggctggtgctattagtaatggt
gcttctgctactttgtggaaaaaggggcatccaaataaacctgaaggtattgcagtaatt
gaagttgatgatccacttgccgctatgcagacacttgctcgttattatttgcgtaaagtt
aatccaactgtagtgggaattactggttcaaatggtaagaccactactaaggatatgatc
gctgcagttttatcaaagcgtttcaacgtacataagactcaagctaattttaataatgaa
atcggcgtgccaatgaccgttcttgaaatgaagccaaatactgaaattttggttcttgaa
atgggaatggatagaccaggacaattacatcacttaagtgaattgactcgtcctgatgta
gctgtaattaccatgattggtgaagctcatattgagttcttcggtagtcgtgataagatt
gctgacgctaagatggagatcactgattttctccgtgaagatggagaatttatttataat
ggtgatgaaccattacttcaagaaagagctaagaagcttgatcaagctaaagcaactttt
ggttttgaagatgatgacacggttcatgctactggttttaagagttacatgcatcatgcg
acttttacaattaatgattcagagcagaaattctctattccaatgatcggtaagcataat
gtttctaatgctatggctgctattagtgttggacgtcattttggtgaaagtgatgaggaa
attgcgtcatcgttgtctaactttaagccaaccgctaatcgtatggaatgggaaaaaggc
gatgttggcgaagcaattatgagtgatatctataactcaaacccaactgcggtaagagct
gttattactagctttggccaagttgaggtaaaagatggcggtcgtagaattgctgttttg
ggtgatatgcttgaattaggtgagaattctccgaagcttcatgccgaattaagcgatact
ttggatccacaaattattaatgaagtatatttatacggccctgaaatgaaaaatctgtat
gatgcattacaaggcaagtatgagtcagagcatttgcattactatactaaagatcaaatg
gatcgtatgattgatgatcttaaaaatgatattaagtcggacgacattgttgtgttgaaa
ggttcacacgggatgcacctagaaaatgtcttagcccgactaagatag
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