Lingula anatina: 106175564 Help Entry 106175564         CDS       T04921                                  Name (RefSeq) E3 ubiquitin-protein ligase UBR4   KO K10691   E3 ubiquitin-protein ligase UBR4 [EC:2.3.2.27] Organism lak  Lingula anatina Brite KEGG Orthology (KO) [BR:lak00001]  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04121 Ubiquitin system [BR:lak04121]     106175564 Enzymes [BR:lak01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      106175564 Ubiquitin system [BR:lak04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    UBR box proteins     106175564 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  E3_UBR4_N E3_UbLigase_R4 UBR4 zf-UBR Motif Other DBs NCBI-GeneID:  106175564 NCBI-ProteinID:  XP_013413082 UniProt:  A0A1S3JRZ1 LinkDB All DBs Position Unknown AA seq 5252 aa AA seqDB search MAGSAEVDWSSCVKPLLPASNSSFIPAEIPDVVEFILKSFSDSQLLTHDEEYEGFYSSYV ALACHYLSANAGEIPKSNLSSTLTACKILLNFLLSRLQDRNENCTISQKYLMILISGLCK GTASLPKSDLLTFTAMLKSAKLPPHIRPEDKEGTEEVAASSQVELKRPRLDTGVNIFDHL TSVFDDTGQIGQGQGPVESMTSDGDMTISHIPDPTEDTRKIFAAKNCIALQQLHGGPILV EACTKLVYVARYRLRYEDAIGGTHKGFVFPGLVSEANSVKLALQSLSNDLSFILRAFSLP ILEPLTTDRLDSIVKVVMTCLYTALTVAAAGSIMNLAASAQVKGATATKEEDFDTYAVGI VQKSLEVFNTVLTTIQSSTRAGGHTLQNYKMTAAWLILHGLQHILHISPSSILDKPKEKE VSKTKTEGTAKPKEGSTGKPAVPKSQHGFGVLAVALASQAMQLMAALMEDLSMETATFTS PMSAYPGETVVQIQGSLTAWQRVERITSSVRLTGLLFNILNVAYKKGFNIKCKKSSSTFP YVRASLLKKQRQGNSESDCDNNDSDSTSSDSNTYYEDDFSCTEDSSSSSEEEDDDSEPIL GLSHWFDETPSPSDSSSNLPPPPPPPVLESSASNASKLGNKIAGEWKNFIPDKKEPDGYI NLATEVLQFLTQHFLSSHCEEVTAYIKSTMGDHQMSLLAFVIKELDRDCSRQENDLFVEF STALARFLHILIASEILSFQLQFTLLQHLGIGTMVSDPWPMTVYPRSLAVLVELILLRQK REREAGCIKSKSEAAVINIWTRFLQSLKNAILNFDNDCEKLEDINVEHLQVLLFLFHGLP LMQKKTILILLGHTIISVAHIDKWKLEEMVPLPLSRLMLIFDYMLHYFYDPPASLMDQVQ HNLFVSHTRSDSSVAVTSEKEYVAFKEVEDNYLKQASAQEMTMKPRFYNLAATGYNNQDT PKVDGLACSFLLGAAEDVLNYSVLYDACVTLLFAGSKWDKVSAGVGTVLEASAIHYHFLI CWRLLGCLPPSAQYMHSLEEGMTEDYDAPHMLHTMRWAPRMMHKNFAGWTKDSLVKQGMT TQKAEALVSSVVNTTNNVNFDVSTALQHMQNELSNTPVMDRSTIVSISDIPSLSSIYMLD TVVAKAHVALDELFTKSMAETDPRKCMEVGLGLLPAVFQLIEAYTVYIRSSLLHQIKEGG EDSSRCHGALRAYGAVLSIGSTRASKVSVLGAATMAYLPEPVRNVIEKWNSSTANEFPAI SSWRNAFANDIIPSESYIEAIQFAHVGTLSGQAEFEVNMSLKHMLQALVRFCQDLVVWCI DSSFNEDLIRVMFPLIFDSTTEYLADYVTLALERVIGPVDGEEYTSRMYLYILQKCYTLL LDMSGPECGLDEKIFHDCLKFMEMHIEKPLGKKAFQTFFTDTGDLTKVLLSASRENMSPT YSTKVLKFFNKLFQLAEKNPQDKCFEVLCSSLKKLARLDMNTLQAWLKKMIMGSPQNLED TAGVSENRHLLQSLTSYIVKENSHVGEEVAKAILNALIPMGSQLLSPSSDGMGFSELMVV MATLAGAGSGVGHTTLFKAATAWLELCKAYLTEKNVIEKLTESVASGNHQVMMESATYLL KYIGDILSALKQSSDKSGSASPHYYGDTGVQEADSDWTEDIAQEEEDSGGEDSDEESLNN KLCTFTITQKEFMNQHWYHCHTCKMVDGVGVCTICAKVCHKDHELTYAKFGSFFCDCGAK EDGSCKAMVKRVSSSDLDGSTLATTPSPFSMEAMLPSSLRQRYSSPDTGDKDRDKDRDSA KISKAREVLCKQVEAQREVLLSHVESSGTASTVLELLQAMTVPIQGHYTRVSPVGSAARA RKALEELHSLTKTVETTDQLMTATLGSQEGAFENVKINYSGEQGQQIRQLITFSLVRRIA MCCMTSVHGKRQHLAVCHEKGKITILQLSTLLKQADSSKRKLTLTRLASAPIPFTVLSIA GNPCNEDFLAVCGLKDCHILTFTSSGSVADHLVLHPQLETGNFIIKALWLPGSQTELAVV TADFVKIYDLAVDALSPQYYYLLPSGKIRDATFMFSEDSRSLVLMSSAGYVYTQVMDEAS SAKHGPFYITNVLEIKHADLKEHQGQIAGGGASIYYSHPLQLLFFSYSQGKTFAAPLPKD ATELPILFPITFKSSSNGGSNGQGSGGSGGASGGGGGGKSNFSQPLVQWSEVPGHPGLVC CMTQVSNHPVILMVKPDVILLQEIKVLPSKAKIQDMVAIRHASSSSDQQRTTLILLCEDG SLRIYMANVDQTGFWMSPSMVPQSVLTTLKPAKKKKVTKTGRPTGNVSFPVDFFEHCQEC KDVEFGGNDILQVYNAQQVKHRLNTSGMYIASTKNGGFSIEITNTNTNNVMVSLRVLVGS QALEMAPSHLEIFGRTTQVNISRARWFDLAFTREESLTAEKKMTLFIGPSVDPAGVTMID SIKVYVKTKEAFGWPEDTEEFAEAVPAAAKVAVPSSGVSSIQATEEPVLPPIPLTCTDRL VASSLEVLDGCFATASSEEKEKERQGALDLATTLLTLPTPVTVTQHTKSLMATLFSSKVA YHNHKDQAQLSQVMHCLTAATKDLDAEAYSRLVVTARALAISRPSNLVRYADKEGSTLVG ESALEVTDLESDDHTETLTRSMELDVSESGHFVVQLVDAFWKLHAARPRNPILAPVCAPG LVHTEATVAALVEIIHAFTSCDLDNVNLAAKLYVRMLMCDDPGVSFYCKLAMIRMLRPRH KRKRVFIPSPPRCSTPGVKEEEEDKTERELPRQPPAAPRSAQPVQIAAPELEEDEEDRDE DQYEVVEHPEPMILEPPEAGIPGGPSLEAILGAHMGAHMGGMNYPPVLDIPPDADDEAMV ELAIALSLQEQGQQGGLSLQGLSLGAQRQGTDHSSHYSDTTASAPASDDEAGSTAATEGS TLRTSPAEQGGSESGGSASGSVSGEQNGFTVPVSGRSSAYGDGGQERDTAGGPRSETSSI GLPSGSMRYEVDICEPDIDNDTSHRLHHLRLMLLEKMIGYITELRNIGGVRAIPFMQVLL MLTSDLDSEEERDKAVLDSLLTALLKQMDFKNVQEVVTRTNVNEVQLIILRLLSVFMSRT RAGMKPSGEPPTLISSSTAGALLHCGSVDYCLNTLKSLHSYWKQLPPDEDTASVPGQLLK SHPTTPPPDMSPFFLRQYVKGHANDVFEAYPQLLTEMVLRLPYQIKKIADASPSLASPSF DQVWFQTLSEYMMTQQTPFVKRQVRKLLLFICGSKEKYRQLRDMHALDAYMKEVRNICEK YGMNVTKPSTHPIVIPYDTLITLIEQLKSCAEIATTRTANWQKFCHKEDTILSFLIQASI CLSDGVAPVLLQLLQCALCGTKISQLQAPPAGASAKAKKEKEKSEEGEEAPPKHDEGLSI ILVQQVNKFVDRELLIQFMRAFLLESNSTAVRWQAHALVLHIYRNSSLSQQEALLCLMWN IWPELPSYGRKTAQFVDLLGYFVLKTPQGSDRRCKEFVEKAVDVLRGQNQILANHPNASI YNMLQGLVEFDGYYLESDPCLVCNNPEVPYNNLKLAAIKVDSKFTTTTQIVKLVGSHTIS KISLKITDLKRTKMVRTLNIYYNNRSVQGIVELKNRSDLWHRAKRVTLTAGQTEAKIEFP LPIVACNLMLEYADFYDNFQASVETLQCPRCSVSVPANPGVCGNCGENVYQCHKCRAINY DEKDPFLCNSCGFCKYAKFDFTMYAKPCCAVDPIENEEDRKKAIQTINNLLEKADRVYKQ LQMNRPTLETQLIRITEHGGDRLLEEVAVTTGTAAGSSVNRCIQQLAQKYCGDCKSSFDE LSKIIQKVLASRKELVEYDRQQKEAATVALAQTGLGSHDEDGAPCEPVMRQSLRLMASGQ CYGCSSSAVEHCVTLLRALSTNPQLRQILCEEGLIKELVNYNLRRGSLLMRNDVRQLVCL LTKDNPEATDNLNNILCGRIMSAMKNYLPNMDLGSLVRHEIMLLANTIQKEDKCWEQRIS AVLKLFLLGMEIKNPTVMENVTLPCLKILQSLIKPEPPTSKKNKDKSMEALSSVRTDIPG LRAHARGWLEGEQACSYTAWKQGQPAKVPESTPKKKKEKEKEKSDEKKKEKDGHGKDADK EEKKTGRKVDKEEVRRVKVRYLMEKYGTRWKNKVKKGDMSMRQMTLPTDSWLCQAIFCPS SRSTRQTACNIVDTICVNPCRRQEMLKVLTSYLDDLGTVGESANEFLALYKRLIAPSTWK YYLAIKGLLPHIGELIAKEIDHLSVLEETTLSSDLSQGFALKALTGLLSSFVEEESIKQH YKSKLVGTVLNGYLSLRKLVVQRTKLIDETQDKLLELLEEMTTGTEEETKEFMAVCINTV KKYSLSDLRSPVFIFERLCSIIYPEENDVSEFFMSLEKDPQQEDFLQGRMLGNPYTSNEP GLGPLMRDVKNKICQDCELVALLEDDTGMELLVNNKIVSLDLPVKDVYKKIWLTNHSEDE PMRVVYRMRGLLGDATEDMVNSLDTSGDEDVDSEEVYKMAAVMAKCGGLEVMLQRMAAIR DLTTGKSLMMVLLKLFNYCVKVKVNRSQLIKPEMNAISIMLGALNLALLAEQEHGTSTTK GQTITEQILQIMEGILLEASEQTPAEYKQFSKLCGEKKQLMMLLDRINSPFVRANASVLQ GLMRLIPFLAFGEEEKMLTLVNHFKPYVNFNKFDFEHTQDEQIHLDCFCVITNAIESNAN GTKLKDMIVEHEIVKDAVEYIQVHAPQVKTLLATDTEDWKEFYSKPCLSYVLRLLAGLCK GHELTQSYVSRDLIPILHKLEQASSEEGVGTLAENLMETLKENQQALAKIGEIRQQTKGE KKRLAMAMRQKQLGALGMTTNEKGQVTVKSSVLKQMEDLKEETGLTCCICREGYRYQPTK VLAIYTFTKRVNLEDFENKQRKSQGYSTVSHFNVIHVDCHNAAVRHARGREEWESAALQN ANTKCNGLLPLWGPQVLENAFAGALARHNSYLQECTGMRDTSYTLTLHDLKLLLLKFALE KSFSDDSGGGGRQSNVHLVPYLMHMTLYVMNTTRSVPREEKNLVTFLHTPREKWVESAYE VDGPLFWSVLALTILNRDRWKEHRVMILKRLLVLAHARHLAPGGATSLADKTVKDYAVYK PMLVFFGLLNSIMLEMYKKVPQTSEGSWSTSLAEFIRRNDKPVLEAADKMVKTYEEEMLP CESFGEFCDVMGLLEEISNPEEFLAHLLSSLP NT seq 15759 nt NT seq  +upstreamnt  +downstreamnt atggcaggaagtgcagaggtagactggtcatcttgtgtaaaacctctgctacctgcgtct aattcaagttttatcccagctgaaataccagatgtagtagaattcattctaaagagtttc agtgattcccagctgttgacacacgatgaagaatatgaaggtttctattcttcctatgtg gcccttgcatgccactatctcagtgccaatgctggggaaatcccaaagagcaacctctcc agcaccctgacagcctgcaagatcctgctgaatttcttgttgtcaagactgcaggacaga aatgagaactgcaccatatcacagaagtacctgatgatcctgatatctgggctgtgcaag gggacggccagtttgcccaaatctgacctcttgacctttacagccatgttgaagtcggcc aagctgccaccgcacatcaggccggaggacaaagagggaacagaagaggttgctgcctcg tcacaagttgagttgaagcgccccagactggacactggggtgaacatctttgaccatctg acctcagtatttgatgacactggacagataggacagggccaaggtccagtggagagtatg accagtgatggcgacatgaccatctctcacatcccagatcctactgaggacaccagaaag atctttgcagccaagaactgtatcgccctacagcagttacacggagggccaatcctggta gaagcctgcaccaagctggtctacgttgccagatacaggctgaggtacgaggatgccatt ggagggactcacaaaggatttgtgttccctggacttgtcagcgaggccaactctgtgaaa ttggcccttcagtctctgtccaatgacctgtccttcatccttcgggccttctccctgccc atactggagccactgaccactgaccgactggacagcatagtgaaagtggtcatgacatgc ctgtatactgcactaaccgtggctgcagctgggagcatcatgaatttagctgcctctgcc caagtgaaaggtgccactgccaccaaggaagaagactttgacacatacgcagtgggcatt gtccagaaaagtctggaagtgtttaacaccgtgctgacaaccattcaatcctctacaagg gcaggtggacataccctacaaaactacaaaatgacagcagcgtggttgatactccatggt ctccagcacattctccatatctctcccagtagcatactggacaaacccaaggagaaggaa gtgtctaaaacaaagactgagggcacagctaaaccaaaagagggcagcactggcaagcca gctgtgcctaaaagtcagcatgggtttggtgtcctagctgtagccctggcctcacaagcc atgcagttgatggcggctctcatggaggatcttagcatggagactgcaacattcacttca cccatgtctgcctatcctggggagactgttgtccagattcagggctctttgactgcctgg cagagagtagaaaggataaccagcagcgtccgactcactggattgctctttaacatactg aatgtggcttacaaaaagggtttcaacattaagtgcaagaaaagtagcagcacctttcca tatgttagggcatccctgttgaagaagcagaggcaaggcaacagtgagtcggactgcgac aataacgacagtgacagcaccagctccgactccaacacgtactatgaggatgacttcagc tgcactgaggacagtagcagcagcagtgaggaagaagatgatgactcagagcccatcctt ggtctgagccactggtttgacgaaaccccctccccctcggactccagcagtaatctgccg ccacctcctccaccccctgtgttggagagctcggccagcaatgccagtaaactggggaac aagatagctggggagtggaagaattttatccctgacaagaaagagcctgatgggtatatc aacctggccacagaagttctgcagttccttacccagcatttcttatcctctcactgtgag gaagtcactgcttatatcaagagtaccatgggggaccaccagatgtcgctgttggcattt gttatcaaagagctggacagggactgcagcaggcaggaaaatgacctgtttgtagaattt tcgacagctttggccaggtttctgcacatactgatagcttctgagatactctcgttccag ttacagttcaccttgctccagcatctgggtataggcaccatggtttctgatccctggccc atgacagtctacccgcggagcttggctgtgctggtggaattgatcctcctaagacagaag agggagagggaggcgggctgcatcaagagtaagagtgaagccgcagtgatcaatatctgg acccgcttcttgcagagcctgaagaatgccatcttgaattttgacaatgattgtgagaaa ttagaagatatcaatgtggagcacctgcaagtgctgttgtttttgttccacgggctgcca ctgatgcagaagaagaccatcctgatattactaggacatactatcatcagtgtggcacac attgacaagtggaaactagaagaaatggttcctctgcccttgtccagactgatgctgatc tttgactatatgctccattacttctatgaccctcctgcctctctcatggaccaggtccag cacaacctgtttgtatcccacaccaggtcagacagcagtgtggctgtcacctcagagaag gagtatgtggcatttaaagaagtggaagacaactacctgaaacaagcctcagcacaagag atgaccatgaagccgaggttctacaacctggcagccactggctataacaaccaggacacg cccaaagtggacggactggcatgcagttttctcctaggagcagcagaagatgtcctgaac tacagcgtcctctatgatgcctgtgtgacattattgtttgcaggatctaagtgggacaaa gtgtctgctggggtaggaactgtattggaggcgtctgccatccactaccacttcctgatc tgctggaggcttctgggatgtctgcctccctccgcgcagtacatgcacagtctagaggaa ggcatgacagaagattacgacgcacctcacatgttacacacaatgcgctgggcgccacgc atgatgcataaaaactttgcaggatggaccaaggactcactggtcaagcagggaatgacc acccagaaagctgaggccctggtctccagcgtggtcaatactaccaataatgtcaacttc gatgtgagcactgcactgcagcacatgcaaaacgagctgtctaacacgccagtaatggac aggtccaccatagtgtccatatcagacatccccagtctgagctccatctacatgctggac actgtggtcgccaaggcacatgtggcactggatgaactcttcactaagtctatggcggag acagatcccaggaagtgtatggaggtagggttgggattgctgcctgcagtgtttcagctg atagaggcttacactgtgtacattaggtcgtccctcctgcatcagatcaaggagggtggc gaggactccagcaggtgtcatggagcactgagagcctatggggctgtccttagtattggc tccactagggccagtaaggtgtctgtcctgggggctgccaccatggcctacctgcctgaa cctgtcagaaatgtcattgagaagtggaacagcagtacagctaatgagtttcctgctatc agctcatggagaaatgcctttgccaatgacattatcccatcagagagttacattgaagct atacagtttgcccatgtgggaactttatcaggccaggcagagtttgaagtgaacatgtca ctgaagcacatgttacaagctttagtcaggttctgccaggacttggtggtatggtgcatt gactcaagcttcaatgaagacctgataagagtaatgttccctctcatctttgacagcacc acagaatatttggctgattatgtgactctggccttggagagggtgataggtcctgtggat ggggaggagtataccagcagaatgtacctgtatatcttacagaagtgttatactctgtta ctggacatgtcaggaccagaatgtggtcttgatgagaagattttccatgactgcttgaag ttcatggagatgcacatagaaaaaccactgggaaagaaagcctttcagaccttctttact gatactggagatttgaccaaagtcctgctgtctgcctccagagaaaacatgtcccctacc tacagcactaaggtgttgaagttcttcaacaaacttttccaacttgctgagaaaaaccca caagacaagtgttttgaagttctctgctcctccctgaagaaactggccaggttggacatg aacaccctgcaggcatggctaaagaaaatgatcatgggctctccacaaaacctagaagac acagctggggtgagcgagaaccgccatcttcttcaaagcctcacatcgtacatcgtaaaa gagaacagccatgttggtgaggaggtggccaaggccattctaaatgctctcattcccatg ggctctcagctcctctctccatcctcagacgggatgggtttctctgagctgatggttgtc atggcaaccctggcaggagctggcagcggagttggtcacactacactgttcaaggcagcc acagcatggctggagctgtgcaaagcctacttgactgagaagaatgtaatagagaagctg acagaaagtgtggcatctggaaatcaccaggttatgatggagagcgccacctatcttctg aagtacataggagacattctgagtgcactgaaacagtcctctgacaaaagtggctctgcc tccccacattactatggcgacactggcgtccaggaggcagacagtgactggacggaggat atagcacaggaagaggaagactctgggggtgaggactccgacgaggaatcactgaacaac aaactgtgtacttttaccattacccagaaggaattcatgaaccagcattggtaccactgt cacacttgcaagatggtagatggcgttggtgtctgcactatatgtgccaaggtgtgccac aaggaccatgaattgacctacgccaagtttggctcctttttctgtgactgtggagcaaaa gaagatggtagctgtaaggccatggtgaagagggtatcttccagtgacctagatggcagc accctcgccaccaccccctcccctttcagtatggaggccatgctccccagctcactgcgc cagcgctactcctcccccgacactggagacaaggacagagataaagacagagactcagca aagatatccaaagctagagaagtgctctgcaaacaagtggaggcccaaagggaggtcttg ctgtctcatgttgaatcatctggaactgccagtactgtgctagaactgctccaggccatg acagtccccatccaaggtcactacacccgagtgtctccagtagggagcgcagccagggca cgcaaggctctggaggaactacactcactgaccaagacagtggaaaccactgaccaactc atgactgccaccctgggctcacaagagggcgcttttgagaatgtcaagataaactacagt ggagagcagggccagcagatacggcagctgatcacattttctctagtgcgccgtatcgcc atgtgctgcatgacatctgtgcacggcaagagacagcaccttgcggtgtgccatgagaag ggcaagatcaccatactgcagctgtctaccctgttgaagcaggcggattctagcaagagg aagctgactctcactagactagcctcggcacctataccattcactgtgctttcaattgct gggaacccgtgtaatgaagattttttggcagtttgtggattaaaggactgccacatcttg acgttcaccagctcagggtcagtagctgaccacctggtcctccaccctcagctggagact ggaaacttcatcatcaaagctctctggctgccaggctctcagactgaactggctgtggtc actgcagactttgtcaagatttacgacctggctgttgacgctctcagtccccagtactac tatctcctgcccagtgggaagattcgagatgctaccttcatgttcagcgaggacagtcgc agtctggtgctgatgtcgtctgctggatacgtctacactcaggtcatggatgaggccagt agtgccaagcatggacctttttacatcactaatgtcttggaaatcaaacatgctgactta aaggagcaccagggccagatagcaggaggtggggcttccatctactactcacaccccctc cagctgttattcttcagctactcacaagggaagacatttgctgcaccgctacccaaggat gccacagaactacccatcctcttccctatcacctttaaaagcagttccaatggcggcagc aacgggcagggcagcggaggcagtggtggagccagtggcggaggaggaggaggaaagagt aacttctcccagcccttagtccagtggtctgaggtacctggccacccgggcctagtgtgc tgtatgacccaggtcagcaaccacccggtcatcctgatggtcaaacctgatgtgattttg ctgcaggagatcaaggtgctgccatctaaggccaagatccaggacatggtcgccatccgc catgcctcctccagctcagaccagcagaggaccaccctgatcctcctgtgtgaggatggc agtctgaggatctacatggccaatgtggaccagactgggttctggatgtccccctctatg gtgccccagtctgtgctgaccacactgaaacctgccaagaagaagaaggtcactaagaca ggtcgtccaacaggcaatgtatccttcccagtggacttctttgagcactgccaggagtgc aaggatgttgagtttggtggcaatgacattctacaggtgtataatgcacagcaggtgaaa cacagactgaacaccagcggcatgtatattgccagtactaagaatggaggattcagtatt gagatcaccaacacaaacaccaacaatgtgatggtatctctcagagtactggtggggagc caggctttggagatggccccctcacacctagaaatctttggacgtactacccaggtcaat ataagtagagcaaggtggtttgatttggcattcactagggaggaaagtcttactgctgag aagaagatgactctatttattggtcccagtgttgacccagcaggtgtcaccatgatagac tccatcaaggtctacgtgaagaccaaggaggcctttggctggccagaggacactgaggag tttgctgaggctgtcccggctgctgccaaggtagcagtgccctctagtggagtgagcagt attcaggccacagaggagccagtgctgccacctatacctctgacatgtacagacagactg gtcgccagttccctggaagttctagatggttgttttgccacagccagttccgaggagaag gagaaggagagacagggggccctggacctagccaccactctgcttaccctgcccaccccc gtcactgtgacccagcacactaagtcactgatggccaccctgttcagcagcaaagtggcg taccataaccacaaggaccaggctcagctatcccaggtgatgcactgtttgactgcggcc accaaggacctggatgctgaggcttactccagactggtggtgaccgccagggctctggcc atctcacggcccagtaacctggtcagatatgctgacaaggagggcagtactttggtggga gaatcggctctggaagtgaccgaccttgaatcagatgaccacacagaaaccttgaccaga agcatggagctggacgtgtccgagtctggccattttgttgtccagctggtggacgccttc tggaagcttcacgcagcaagaccccgtaatcctatcctggcaccagtttgtgccccaggc ttggtgcacactgaggccacagtggcagccctggtggagatcatccacgccttcacctcg tgtgacctggacaatgtgaacctggcggccaagttgtacgtcaggatgctgatgtgtgat gatccaggagtgagtttctactgcaagctggccatgattagaatgctgagaccaagacac aagcggaagagagtcttcattccttcccctccaaggtgcagcactcctggtgttaaagag gaagaagaggacaaaactgagcgagaacttccccgccagcctcctgctgcacccaggtct gcccagcctgtccagatagctgccccagaactggaggaggatgaggaggatagggatgag gatcagtatgaagtggtggaacatccagaacccatgatactggagccccctgaagctggc ataccaggagggccgtcactggaggccatccttggggcccatatgggggcccacatgggg ggcatgaactaccctcctgtgctggacatcccccctgatgctgatgatgaggccatggtg gaactggccatcgctcttagtctccaggaacagggtcagcagggcggtctgagtctacag gggctgagcttgggagcacagagacaaggtactgaccacagcagccattattcagacacg acggcatcagcaccggccagtgacgatgaggcaggcagtacagcggccacagaggggtca actctcaggacatccccagcagaacagggagggtcggagagtggagggagcgcaagtgga tctgtgtctggagaacagaatggtttcactgttccagtgagtggtcgtagcagtgcctat ggtgatggcggtcaggagagggacacggcagggggaccgcgcagtgagaccagcagtatt ggcttaccctcgggatccatgagatatgaggttgacatctgtgagccggatatagacaat gacactagccacagattgcaccacctgcgtctaatgctgctagaaaagatgataggatat atcacagagttgaggaacattggtggagtgagagccataccttttatgcaggtgctcctg atgttgacctctgacctggacagtgaggaggagagggacaaggcagtactggacagcctg ctcacagctctgctcaaacagatggatttcaagaatgtccaggaggttgtgaccagaaca aatgtgaacgaggttcagctgataattctccgccttctcagtgtgttcatgtccagaaca cgggcaggcatgaagccctctggggagccaccaactctgattagttccagcacagcaggt gccctgctgcattgtggttctgtggattactgcctcaacacactgaagagtttgcactcc tactggaagcaactgcctcctgatgaggacactgcctcagtaccaggacaactgttgaaa agtcaccccaccaccccgccacctgacatgtcccccttcttcctacgacagtatgtgaag gggcacgcaaacgacgtatttgaggcctacccccagctcttgacagagatggtcctcaga ctgccgtatcagatcaagaagatagcggatgccagccctagcttggcgtcaccctcattt gaccaggtttggtttcagacgctgtcggagtacatgatgacacagcagacgccatttgtg aagagacaagtgagaaagctccttctgttcatctgcgggtccaaagagaaataccgtcag ctgcgggacatgcatgctttggatgcctacatgaaggaagtgaggaacatatgtgagaaa tatggcatgaatgtcaccaagccaagcactcaccctattgtcataccatatgacacactg ataacactgattgaacagctgaagtcctgtgcagagattgccaccaccaggactgccaac tggcaaaagttctgccacaaggaggacaccatcttgtccttcctgatccaggctagtatc tgcctgagtgatggggtggcgccagtgttgctgcagctgctgcagtgtgccctctgtggt accaagataagccagctccaagccccaccagcaggagcctctgccaaagctaagaaggaa aaagagaagtcagaagagggagaagaagcgccaccaaaacatgatgaaggcctcagcatt atcttagttcaacaagtcaacaagtttgtagatcgtgaactcttgattcagtttatgaga gctttccttctggagtccaactccacagctgtgcgctggcaggctcacgccttggtactg cacatttacaggaattcctccctgagccagcaggaggcgttgctgtgtctcatgtggaat atatggccagagctgccctcgtatggcaggaaaactgcccaatttgtggacctcctgggc tactttgtcctcaagaccccacagggctcagaccggaggtgtaaagagtttgtagagaaa gccgtggatgtgttgagaggacagaaccagatcctggccaaccatcccaatgccagcata tacaatatgctgcaggggctggtggaatttgatggctactacctggagagcgacccttgt ctggtgtgtaacaaccctgaggtcccatataataatctgaagcttgctgccatcaaggtg gactccaagttcaccaccaccactcagatagtgaaactagtgggaagtcacaccatctcc aagatatcactgaagataaccgacctgaagagaaccaagatggtccgtaccttgaatatc tactacaacaacagatcagttcaggggattgtggagctgaaaaataggtctgatttgtgg cacagagccaagagagtgactcttactgcaggacagactgaagccaagattgagttccct ttgcccatcgttgcttgcaacctaatgctggagtatgccgacttctatgacaacttccag gcctcggtggagaccctgcagtgtccccgctgtagtgtatctgtaccagccaaccctggg gtctgtggaaactgtggagagaacgtctaccagtgccacaagtgcagggccataaactat gatgaaaaggacccattcttgtgtaactcctgtggcttctgcaagtatgccaagtttgac ttcaccatgtacgccaagccttgctgtgccgtggaccccattgagaatgaggaggacagg aagaaggccatccagaccatcaataacctgctggagaaggcggaccgtgtgtacaagcag ctccaaatgaacagacccaccctggagacacagctgatcaggattactgaacatggcgga gacaggctactggaggaggtagctgtaactacagggacagcagcaggctctagtgtcaac agatgtatacagcagttggcacagaagtactgcggggactgcaagtcctcctttgatgag ctgagcaagataatacagaaagtgttggcatcacgtaaagagctggtagaatatgacagg cagcaaaaagaggctgccactgttgccctggcgcagactggactggggtcacatgatgaa gatggcgccccctgtgagcctgtgatgagacaaagtctgcggctgatggcgtccggccag tgttatggatgttccagttctgctgtggagcactgcgttactctgcttagagccctcagc accaacccacaactcaggcagatactgtgtgaagagggcctgatcaaggagttggtgaac tacaacctgcgccggggctccctcctgatgagaaatgatgtccgtcagctggtctgtctg ctgaccaaggacaaccccgaagccacggacaacctgaataacatcctctgtggaagaatt atgtctgctatgaagaattacctgcccaatatggacctgggatctctggtccgccatgag atcatgttgctggcaaacaccatccagaaagaagacaaatgctgggagcagaggattagt gctgtgttgaaactgtttctgctggggatggagattaagaaccccactgtgatggagaat gtcaccctgccctgcctgaagatactacagtctctgatcaaacctgaacctcccacatcc aagaaaaacaaggataagagcatggaggccctgagcagtgtccgtactgatatcccaggg ttgagagcacatgcccgggggtggctggagggagaacaggcctgctcttacactgcctgg aaacaaggacagcctgccaaagttccagaatccactccaaaaaagaaaaaggagaaagaa aaagaaaagtcagatgaaaagaagaaagagaaggacggtcatggtaaagatgcagacaag gaggaaaagaagactggacgtaaggtggacaaggaggaggttcggagggtcaaggtgcgc taccttatggagaagtacgggacgagatggaagaataaagtcaagaaaggtgacatgtcc atgaggcagatgaccctcccaacagacagctggctatgtcaggccatcttctgtccatcc tctcgttccactcgccagacagcctgcaacatcgtagacaccatctgtgtcaacccctgc aggcgccaggagatgctgaaagtgctcactagctatctggatgacttgggcactgttgga gagagtgccaatgaattcctggccctgtacaagagactaatagctccctctacctggaaa tactacctggccattaagggactgctgccacacataggagagctgatagccaaggaaatt gaccacctgtcagtgctggaggagaccaccctcagctcagacttatcccaaggatttgct ttgaaggcactcacaggtctgctgtcctccttcgttgaagaggagagcatcaagcagcac tacaagagcaagctggtggggacggtcctcaatggctacctgtccctcaggaagctggtg gtccagaggaccaagctgatcgatgagacgcaggacaagttgctggaactcctggaagag atgaccacagggacggaggaggagaccaaggagttcatggccgtctgtatcaacacagtg aagaagtacagtctcagtgatctcaggtctcctgtcttcatctttgagaggttgtgcagt ataatatatccggaggaaaatgatgtgagtgagtttttcatgtcgctggaaaaagaccca cagcaggaggacttcctgcaggggaggatgctgggaaatccatacacgtccaatgagccg ggacttggtcctcttatgagagatgtcaaaaacaagatttgtcaagattgtgagctggtt gccctgttggaagatgacacagggatggagttactggtgaataacaagatagtcagtctg gacttgcctgtaaaggatgtctataagaagatctggctcaccaaccattctgaggatgag cccatgagggttgtctacaggatgagagggttgctgggagatgctacagaggacatggtc aactcactggacaccagtggagatgaagacgtagatagtgaagaggtttacaagatggct gcagtgatggccaagtgtggtggcttggaggttatgttgcagaggatggcagccattagg gatctaactacaggaaagagcttgatgatggtgctcttgaaactgttcaattattgtgtc aaggtcaaggtcaacagaagtcagctgatcaagccagagatgaacgccatcagcattatg ttaggagcactgaacttggctctcctagcagagcaggaacatggcactagcaccaccaag gggcaaaccattacagaacagatcctgcagatcatggagggtattttactggaggccagt gaacaaacacctgctgagtacaagcaattctccaagctgtgcggagagaagaaacagctg atgatgttgctggacagaatcaacagcccctttgtgcgcgccaatgccagcgtactgcag ggactgatgagactgattcccttcctggcctttggagaggaagagaagatgttgacactg gtgaaccatttcaagccttatgtcaattttaacaagtttgactttgagcacactcaagat gaacagattcatctggactgcttctgtgtcatcactaacgcaatcgagagtaatgccaac ggtaccaagctgaaggacatgatagtagagcacgagatcgtgaaagacgcggtggagtac atccaggtgcacgcgccacaggtcaagacactgttagcaactgataccgaggactggaaa gaattctactcaaaaccttgcctgagttatgtgctgagactgctggctgggctatgcaaa ggacacgaactgacacagtcttatgtgagcagggatctgatccccatcttgcacaagctg gagcaggcgtcctctgaggagggagttgggacactggctgaaaacctcatggagaccctg aaggaaaaccagcaggcactggctaagattggagagattcgtcagcagaccaagggagag aagaagaggttggctatggccatgagacagaaacaactgggagcattgggcatgacgacc aatgagaagggccaggttactgtgaagagctctgttctaaaacagatggaagacttgaag gaagagacaggtctgacgtgttgtatatgtagagaggggtacagatatcagcccaccaag gtgttggccatctatacgttcaccaagcgtgttaacttggaagattttgagaacaagcag aggaagagccagggatactccactgtgtctcacttcaatgtgatccatgtggactgtcat aatgcagctgtcagacatgcacgtggccgtgaggagtgggagagcgcggccctacagaat gccaacaccaagtgtaacggcctcctcccactgtgggggccgcaggttctggagaatgcc ttcgctggagccttggccaggcacaactcctatcttcaagaatgtactgggatgcgggac accagctataccctcaccttacacgacctcaagctgctgttactgaagttcgccctggag aaatccttcagtgatgacagtgggggtggcggacgccagagcaatgtgcacctcgtcccc tacctgatgcacatgactctctatgtgatgaacacgacccggtctgtgcccagagaggag aaaaacttggtcaccttcctgcacacacctagagagaagtgggtggagtctgcctatgag gtggacggtcctctgttctggtcagttttggccttgaccatcttgaaccgagaccggtgg aaggagcacagagtcatgatcctgaagaggctgctggttctggcccatgccagacacctg gcaccaggtggagccactagtctggcagacaagaccgtgaaggactatgccgtgtacaag ccgatgttggtgttctttggtttgctgaactcaataatgctggaaatgtacaagaaggtt ccgcagacgtcagaggggagttggtcgacctctctagcagagtttattcgtcgcaatgac aagcctgtgctggaggccgcagacaagatggtcaaaacctacgaagaagagatgctaccg tgcgagtcttttggagaattctgtgatgtcatgggactcttggaagaaatctccaaccct gaggagtttttggcccacttgctgtcgtctctgccttag

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