Lacimicrobium alkaliphilum: AT746_15950
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Entry
AT746_15950 CDS
T04189
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
lal
Lacimicrobium alkaliphilum
Pathway
lal00260
Glycine, serine and threonine metabolism
lal00261
Monobactam biosynthesis
lal00270
Cysteine and methionine metabolism
lal00300
Lysine biosynthesis
lal01100
Metabolic pathways
lal01110
Biosynthesis of secondary metabolites
lal01120
Microbial metabolism in diverse environments
lal01230
Biosynthesis of amino acids
Module
lal_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
lal_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
lal00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
AT746_15950 (thrA)
00270 Cysteine and methionine metabolism
AT746_15950 (thrA)
00300 Lysine biosynthesis
AT746_15950 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
AT746_15950 (thrA)
Enzymes [BR:
lal01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
AT746_15950 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
AT746_15950 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
ThiF
UCR_Fe-S_N
Motif
Other DBs
NCBI-ProteinID:
ALS99604
UniProt:
A0A0U2ZAS8
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All DBs
Position
complement(3527562..3530015)
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AA seq
817 aa
AA seq
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MKVMKFGGSSLADAERYLRVRDIVLHTHTEKGAAVVLSAPKGVTNALSLLVEQAVAGDPW
QELFEKLNMTLTGIVKDLANELDNFDHQPLLTLIDEKLLELKQSLEGIHLLHCSPDAVTA
KLLSIGEYVSVNIFSGIISAMGVSNQIIDPVEYVLAEGDYLDSIADVAASRARFTNVPKN
GEQMLIMPGFVAANEKGEKVTLGRNGSDYSAAILAACIDAQCCEIWTDVDGVYNADPNQV
DGAVLLDKLTYQEAMELSYFGAKVLHPKTIGPIAQYHIPCLIRNTLNPSAPGTLISTEAS
DTWTSVKGISHLSDITMFNVAGPGMKGMVGMASRVFEVISNANISISLITQSSSEYSISF
CVHAKDAQRAKHLLEEAFVLELANQLLEPIEMRESVAIVTLVGDGMRKAKGLAARFFSSL
AQARVNIVAIAQGSSERSISAVIESRKAREAVKVVHQNFFSNLHTIDAFLVGCGTVGSEL
LEQIARQQQQLLGRNINLQVYGIANSKGMLLQPGGIDLKNGWRDQLAQRQQPFSLAVMEN
FVQDNSLINPVIIDCTTSTAIADQYLDMMEAGFHVVTPNKKANTAGMDFYAALREKAQST
RRQFLYETTVGAGLPVIENLQKLLYAGDELTRFEGILSGSLSYIFGKLEEGLSLSEATKI
AREKGYTEPDPRDDLSGMDVARKLLIMARESGLKLELKDIEIESILPDDFDDSGSVEEFL
SRLPQLDQLYKQQLEQNPGKVLRYVGSIEEGHCKVGIQAVDNSHPLYVVKDGENALAIHS
HYYQPIPFVIRGYGAGAAVTAAGVFADVLRTMPWKQE
NT seq
2454 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtgatgaaatttgggggctcgtccttagccgatgccgagcgctatctgagggtc
agagacattgtgctgcacacccatactgagaaaggtgcagcggtggtcctctcggcgccc
aaaggagtcaccaatgccttatcgctgctggtggagcaggctgttgccggtgacccctgg
caggagctgtttgagaagctgaatatgaccctgaccggcattgttaaggatctcgccaat
gagctggacaattttgaccatcagcccctgctcactctgattgatgaaaagctgctggag
cttaaacaaagccttgagggcattcatcttcttcattgcagccccgatgccgtaaccgcc
aagctgcttagcattggtgaatatgtcagcgtaaatattttcagtggcatcatcagcgcc
atgggcgtcagcaatcagattatcgacccggtggaatatgtgctggcagagggcgactat
cttgacagtatcgccgatgtggccgccagccgcgcccgctttactaatgtgccgaaaaac
ggcgagcagatgctgattatgcctggttttgtagcggccaatgaaaaaggtgaaaaagtt
acgctgggacgtaatggctcagattactcggcggctattctggcggcctgtatcgatgcg
cagtgctgtgagatctggactgatgtggacggggtgtataacgccgaccctaaccaggtc
gatggcgcggtactgctggataaactcacctatcaggaagccatggagctgtcttatttc
ggcgccaaggtgttgcaccccaagaccattggccctatcgctcagtatcatattccctgt
ctgatccgtaataccctgaatccttcagcaccgggcaccttgatcagtaccgaagccagt
gacacctggaccagcgttaaaggtatttcgcacctgtctgacatcactatgtttaacgtg
gcaggccctggcatgaaaggcatggtgggcatggccagcagggtgtttgaggtgatctcc
aatgccaatatttctatcagcctgatcacccagtcatcctctgagtacagcatcagcttt
tgtgtacatgcaaaagatgcccagcgtgccaagcatctgctcgaagaagcctttgtgctg
gaactggccaatcagttgctggaaccgattgaaatgcgtgagtctgtggccatcgttacg
ctggtcggtgatggcatgcgcaaagctaaggggctggctgcccgtttcttcagctctctc
gctcaggcccgggtcaacattgtggcgattgcccagggctcttcagaacgttctatttct
gcggtgattgaaagtcgcaaagccagggaggccgttaaggtggtgcatcagaattttttc
tcgaatttacatactatagatgcttttctggtgggttgtggcactgtaggcagtgaactg
cttgagcagattgcccgccagcagcaacaactgttaggccgcaatattaatctgcaggtt
tacggtatcgccaacagtaaaggcatgctgttgcaaccaggcgggattgatctgaaaaat
ggctggcgcgatcagttagcacagcgccaacaacctttttcgctggcggtgatggaaaac
tttgtgcaggataacagcctgatcaacccggtgattattgactgtaccaccagtaccgcc
attgccgatcagtatctggatatgatggaagcgggctttcatgtggtaacgccgaataaa
aaggccaacaccgcaggcatggatttttacgctgcgctcagagaaaaagcccagtccacc
cgtcgtcagtttctgtatgaaaccacggtcggtgccggattgccggttattgagaacctg
caaaagctgctttacgccggtgatgaactgacccgctttgagggtatactgtccgggtca
ctgtcctatattttcggtaagctggaagaggggttaagcctgtctgaagccaccaaaatt
gcccgggagaaaggctatactgagcccgacccccgagatgatttaagcggtatggatgta
gccaggaagctgctgattatggcccgtgaatcgggcctgaagctggagctcaaggatatt
gagattgagtccatcctgcctgatgattttgatgattccggctcggtggaggaatttctt
tcccgattaccacaacttgaccagttgtataaacagcaactggaacaaaatccgggtaaa
gtactgcgctatgtaggcagtattgaagaaggtcactgtaaagtggggattcaggcggtg
gataacagtcatccgctgtatgtggtaaaagacggtgaaaatgcgctggctattcacagc
cattattatcagcctattccttttgtgatccgcggttacggtgctggtgcggcggtgact
gccgctggggtcttcgccgatgtactgcgcactatgccctggaagcaggaataa
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