KEGG   Lagenorhynchus albirostris (white-beaked dolphin): 132504703
Entry
132504703         CDS       T10760                                 
Symbol
MAPK3
Name
(RefSeq) mitogen-activated protein kinase 3 isoform X1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
lalb  Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb01521  EGFR tyrosine kinase inhibitor resistance
lalb01522  Endocrine resistance
lalb01524  Platinum drug resistance
lalb04010  MAPK signaling pathway
lalb04012  ErbB signaling pathway
lalb04014  Ras signaling pathway
lalb04015  Rap1 signaling pathway
lalb04022  cGMP-PKG signaling pathway
lalb04024  cAMP signaling pathway
lalb04062  Chemokine signaling pathway
lalb04066  HIF-1 signaling pathway
lalb04068  FoxO signaling pathway
lalb04071  Sphingolipid signaling pathway
lalb04072  Phospholipase D signaling pathway
lalb04114  Oocyte meiosis
lalb04140  Autophagy - animal
lalb04148  Efferocytosis
lalb04150  mTOR signaling pathway
lalb04151  PI3K-Akt signaling pathway
lalb04210  Apoptosis
lalb04218  Cellular senescence
lalb04261  Adrenergic signaling in cardiomyocytes
lalb04270  Vascular smooth muscle contraction
lalb04350  TGF-beta signaling pathway
lalb04360  Axon guidance
lalb04370  VEGF signaling pathway
lalb04371  Apelin signaling pathway
lalb04380  Osteoclast differentiation
lalb04510  Focal adhesion
lalb04520  Adherens junction
lalb04540  Gap junction
lalb04550  Signaling pathways regulating pluripotency of stem cells
lalb04611  Platelet activation
lalb04613  Neutrophil extracellular trap formation
lalb04620  Toll-like receptor signaling pathway
lalb04621  NOD-like receptor signaling pathway
lalb04625  C-type lectin receptor signaling pathway
lalb04650  Natural killer cell mediated cytotoxicity
lalb04657  IL-17 signaling pathway
lalb04658  Th1 and Th2 cell differentiation
lalb04659  Th17 cell differentiation
lalb04660  T cell receptor signaling pathway
lalb04662  B cell receptor signaling pathway
lalb04664  Fc epsilon RI signaling pathway
lalb04666  Fc gamma R-mediated phagocytosis
lalb04668  TNF signaling pathway
lalb04713  Circadian entrainment
lalb04720  Long-term potentiation
lalb04722  Neurotrophin signaling pathway
lalb04723  Retrograde endocannabinoid signaling
lalb04724  Glutamatergic synapse
lalb04725  Cholinergic synapse
lalb04726  Serotonergic synapse
lalb04730  Long-term depression
lalb04810  Regulation of actin cytoskeleton
lalb04910  Insulin signaling pathway
lalb04912  GnRH signaling pathway
lalb04914  Progesterone-mediated oocyte maturation
lalb04915  Estrogen signaling pathway
lalb04916  Melanogenesis
lalb04917  Prolactin signaling pathway
lalb04919  Thyroid hormone signaling pathway
lalb04921  Oxytocin signaling pathway
lalb04926  Relaxin signaling pathway
lalb04928  Parathyroid hormone synthesis, secretion and action
lalb04929  GnRH secretion
lalb04930  Type II diabetes mellitus
lalb04933  AGE-RAGE signaling pathway in diabetic complications
lalb04934  Cushing syndrome
lalb04935  Growth hormone synthesis, secretion and action
lalb04960  Aldosterone-regulated sodium reabsorption
lalb05010  Alzheimer disease
lalb05020  Prion disease
lalb05022  Pathways of neurodegeneration - multiple diseases
lalb05034  Alcoholism
lalb05132  Salmonella infection
lalb05133  Pertussis
lalb05135  Yersinia infection
lalb05140  Leishmaniasis
lalb05142  Chagas disease
lalb05145  Toxoplasmosis
lalb05152  Tuberculosis
lalb05160  Hepatitis C
lalb05161  Hepatitis B
lalb05163  Human cytomegalovirus infection
lalb05164  Influenza A
lalb05165  Human papillomavirus infection
lalb05166  Human T-cell leukemia virus 1 infection
lalb05167  Kaposi sarcoma-associated herpesvirus infection
lalb05170  Human immunodeficiency virus 1 infection
lalb05171  Coronavirus disease - COVID-19
lalb05200  Pathways in cancer
lalb05203  Viral carcinogenesis
lalb05205  Proteoglycans in cancer
lalb05206  MicroRNAs in cancer
lalb05207  Chemical carcinogenesis - receptor activation
lalb05208  Chemical carcinogenesis - reactive oxygen species
lalb05210  Colorectal cancer
lalb05211  Renal cell carcinoma
lalb05212  Pancreatic cancer
lalb05213  Endometrial cancer
lalb05214  Glioma
lalb05215  Prostate cancer
lalb05216  Thyroid cancer
lalb05218  Melanoma
lalb05219  Bladder cancer
lalb05220  Chronic myeloid leukemia
lalb05221  Acute myeloid leukemia
lalb05223  Non-small cell lung cancer
lalb05224  Breast cancer
lalb05225  Hepatocellular carcinoma
lalb05226  Gastric cancer
lalb05230  Central carbon metabolism in cancer
lalb05231  Choline metabolism in cancer
lalb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lalb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lalb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132504703 (MAPK3)
   04012 ErbB signaling pathway
    132504703 (MAPK3)
   04014 Ras signaling pathway
    132504703 (MAPK3)
   04015 Rap1 signaling pathway
    132504703 (MAPK3)
   04350 TGF-beta signaling pathway
    132504703 (MAPK3)
   04370 VEGF signaling pathway
    132504703 (MAPK3)
   04371 Apelin signaling pathway
    132504703 (MAPK3)
   04668 TNF signaling pathway
    132504703 (MAPK3)
   04066 HIF-1 signaling pathway
    132504703 (MAPK3)
   04068 FoxO signaling pathway
    132504703 (MAPK3)
   04072 Phospholipase D signaling pathway
    132504703 (MAPK3)
   04071 Sphingolipid signaling pathway
    132504703 (MAPK3)
   04024 cAMP signaling pathway
    132504703 (MAPK3)
   04022 cGMP-PKG signaling pathway
    132504703 (MAPK3)
   04151 PI3K-Akt signaling pathway
    132504703 (MAPK3)
   04150 mTOR signaling pathway
    132504703 (MAPK3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    132504703 (MAPK3)
   04148 Efferocytosis
    132504703 (MAPK3)
  09143 Cell growth and death
   04114 Oocyte meiosis
    132504703 (MAPK3)
   04210 Apoptosis
    132504703 (MAPK3)
   04218 Cellular senescence
    132504703 (MAPK3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    132504703 (MAPK3)
   04520 Adherens junction
    132504703 (MAPK3)
   04540 Gap junction
    132504703 (MAPK3)
   04550 Signaling pathways regulating pluripotency of stem cells
    132504703 (MAPK3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    132504703 (MAPK3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    132504703 (MAPK3)
   04613 Neutrophil extracellular trap formation
    132504703 (MAPK3)
   04620 Toll-like receptor signaling pathway
    132504703 (MAPK3)
   04621 NOD-like receptor signaling pathway
    132504703 (MAPK3)
   04625 C-type lectin receptor signaling pathway
    132504703 (MAPK3)
   04650 Natural killer cell mediated cytotoxicity
    132504703 (MAPK3)
   04660 T cell receptor signaling pathway
    132504703 (MAPK3)
   04658 Th1 and Th2 cell differentiation
    132504703 (MAPK3)
   04659 Th17 cell differentiation
    132504703 (MAPK3)
   04657 IL-17 signaling pathway
    132504703 (MAPK3)
   04662 B cell receptor signaling pathway
    132504703 (MAPK3)
   04664 Fc epsilon RI signaling pathway
    132504703 (MAPK3)
   04666 Fc gamma R-mediated phagocytosis
    132504703 (MAPK3)
   04062 Chemokine signaling pathway
    132504703 (MAPK3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    132504703 (MAPK3)
   04929 GnRH secretion
    132504703 (MAPK3)
   04912 GnRH signaling pathway
    132504703 (MAPK3)
   04915 Estrogen signaling pathway
    132504703 (MAPK3)
   04914 Progesterone-mediated oocyte maturation
    132504703 (MAPK3)
   04917 Prolactin signaling pathway
    132504703 (MAPK3)
   04921 Oxytocin signaling pathway
    132504703 (MAPK3)
   04926 Relaxin signaling pathway
    132504703 (MAPK3)
   04935 Growth hormone synthesis, secretion and action
    132504703 (MAPK3)
   04919 Thyroid hormone signaling pathway
    132504703 (MAPK3)
   04928 Parathyroid hormone synthesis, secretion and action
    132504703 (MAPK3)
   04916 Melanogenesis
    132504703 (MAPK3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    132504703 (MAPK3)
   04270 Vascular smooth muscle contraction
    132504703 (MAPK3)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    132504703 (MAPK3)
  09156 Nervous system
   04724 Glutamatergic synapse
    132504703 (MAPK3)
   04725 Cholinergic synapse
    132504703 (MAPK3)
   04726 Serotonergic synapse
    132504703 (MAPK3)
   04720 Long-term potentiation
    132504703 (MAPK3)
   04730 Long-term depression
    132504703 (MAPK3)
   04723 Retrograde endocannabinoid signaling
    132504703 (MAPK3)
   04722 Neurotrophin signaling pathway
    132504703 (MAPK3)
  09158 Development and regeneration
   04360 Axon guidance
    132504703 (MAPK3)
   04380 Osteoclast differentiation
    132504703 (MAPK3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    132504703 (MAPK3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    132504703 (MAPK3)
   05206 MicroRNAs in cancer
    132504703 (MAPK3)
   05205 Proteoglycans in cancer
    132504703 (MAPK3)
   05207 Chemical carcinogenesis - receptor activation
    132504703 (MAPK3)
   05208 Chemical carcinogenesis - reactive oxygen species
    132504703 (MAPK3)
   05203 Viral carcinogenesis
    132504703 (MAPK3)
   05230 Central carbon metabolism in cancer
    132504703 (MAPK3)
   05231 Choline metabolism in cancer
    132504703 (MAPK3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132504703 (MAPK3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    132504703 (MAPK3)
   05212 Pancreatic cancer
    132504703 (MAPK3)
   05225 Hepatocellular carcinoma
    132504703 (MAPK3)
   05226 Gastric cancer
    132504703 (MAPK3)
   05214 Glioma
    132504703 (MAPK3)
   05216 Thyroid cancer
    132504703 (MAPK3)
   05221 Acute myeloid leukemia
    132504703 (MAPK3)
   05220 Chronic myeloid leukemia
    132504703 (MAPK3)
   05218 Melanoma
    132504703 (MAPK3)
   05211 Renal cell carcinoma
    132504703 (MAPK3)
   05219 Bladder cancer
    132504703 (MAPK3)
   05215 Prostate cancer
    132504703 (MAPK3)
   05213 Endometrial cancer
    132504703 (MAPK3)
   05224 Breast cancer
    132504703 (MAPK3)
   05223 Non-small cell lung cancer
    132504703 (MAPK3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    132504703 (MAPK3)
   05170 Human immunodeficiency virus 1 infection
    132504703 (MAPK3)
   05161 Hepatitis B
    132504703 (MAPK3)
   05160 Hepatitis C
    132504703 (MAPK3)
   05171 Coronavirus disease - COVID-19
    132504703 (MAPK3)
   05164 Influenza A
    132504703 (MAPK3)
   05163 Human cytomegalovirus infection
    132504703 (MAPK3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132504703 (MAPK3)
   05165 Human papillomavirus infection
    132504703 (MAPK3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132504703 (MAPK3)
   05135 Yersinia infection
    132504703 (MAPK3)
   05133 Pertussis
    132504703 (MAPK3)
   05152 Tuberculosis
    132504703 (MAPK3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132504703 (MAPK3)
   05140 Leishmaniasis
    132504703 (MAPK3)
   05142 Chagas disease
    132504703 (MAPK3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    132504703 (MAPK3)
   05020 Prion disease
    132504703 (MAPK3)
   05022 Pathways of neurodegeneration - multiple diseases
    132504703 (MAPK3)
  09165 Substance dependence
   05034 Alcoholism
    132504703 (MAPK3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132504703 (MAPK3)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    132504703 (MAPK3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    132504703 (MAPK3)
   04934 Cushing syndrome
    132504703 (MAPK3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    132504703 (MAPK3)
   01524 Platinum drug resistance
    132504703 (MAPK3)
   01522 Endocrine resistance
    132504703 (MAPK3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lalb01001]
    132504703 (MAPK3)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:lalb03036]
    132504703 (MAPK3)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lalb04147]
    132504703 (MAPK3)
Enzymes [BR:lalb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     132504703 (MAPK3)
Protein kinases [BR:lalb01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   132504703 (MAPK3)
Chromosome and associated proteins [BR:lalb03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     132504703 (MAPK3)
Exosome [BR:lalb04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   132504703 (MAPK3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase FTA2 Kdo
Other DBs
NCBI-GeneID: 132504703
NCBI-ProteinID: XP_059978234
LinkDB
Position
15:71581038..71587850
AA seq 325 aa
MAWSAYDHVRKTRVAIKKISPFEHQTYCQRTLREIQILLRFRHENVIGIRDILRAPTLDA
MRDVYIVQDLMETDLYKLLKSQQLSNDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLI
NTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCI
LAEMLSNRPIFPGKHYLDQLNHILGILGSPSQEDLNCIINMKARNYLQSLPSKTKVAWAK
LFPKSDPKALDLLDRMLTFNPNKRITVEEALAHPYLEQYYDPTDEPVAEEPFTFDMELDD
LPKERLKELIFQETARFQPGVLEAP
NT seq 978 nt   +upstreamnt  +downstreamnt
atggcatggtcagcttacgaccacgtgcgcaagactcgagtggccatcaagaaaatcagc
ccctttgagcatcagacctactgccagcgtacgttgcgagagatccagatcttgctgcgc
ttccgccacgagaacgtcatcggcatccgagacattctgcgggcacccaccctggatgcc
atgagggatgtctacattgtgcaagacctgatggagacagacctgtacaagttgcttaaa
agccagcagctgagcaacgaccacatctgctacttcctctaccaaatcctgcggggcctc
aagtatatccattccgccaacgtgctccaccgggatttaaagccctccaacctgctcatc
aacaccacctgcgaccttaagatctgtgattttggtcttgcccggattgccgatcctgag
cacgaccacactggctttctgacggaatacgtggctacacgctggtaccgggccccagag
atcatgcttaactccaagggctacaccaagtccatcgacatctggtctgtgggctgcatt
ctggctgagatgctctccaaccggcccatcttcccgggcaagcactacctggaccagctc
aaccacattctgggtatcctgggctccccctcccaggaggacctgaattgtatcatcaac
atgaaggcccgaaactacctacagtctctaccctccaagaccaaggtggcctgggccaag
ctttttcccaagtcggaccccaaagctcttgacctgctggaccggatgttgacctttaac
cccaacaaacggatcacagtggaagaagcactggctcacccctacctggagcagtactac
gacccaacagatgagccagtggccgaggaacctttcaccttcgacatggagctggatgat
ctacccaaggagcggctgaaggagctcatcttccaggagacagcccgtttccagcctggg
gtgctggaggccccctaa

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