KEGG   Lagenorhynchus albirostris (white-beaked dolphin): 132511381
Entry
132511381         CDS       T10760                                 
Symbol
MAP2K6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
lalb  Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb04010  MAPK signaling pathway
lalb04015  Rap1 signaling pathway
lalb04218  Cellular senescence
lalb04380  Osteoclast differentiation
lalb04620  Toll-like receptor signaling pathway
lalb04664  Fc epsilon RI signaling pathway
lalb04668  TNF signaling pathway
lalb04750  Inflammatory mediator regulation of TRP channels
lalb04912  GnRH signaling pathway
lalb04935  Growth hormone synthesis, secretion and action
lalb04936  Alcoholic liver disease
lalb05014  Amyotrophic lateral sclerosis
lalb05022  Pathways of neurodegeneration - multiple diseases
lalb05132  Salmonella infection
lalb05135  Yersinia infection
lalb05145  Toxoplasmosis
lalb05161  Hepatitis B
lalb05163  Human cytomegalovirus infection
lalb05167  Kaposi sarcoma-associated herpesvirus infection
lalb05169  Epstein-Barr virus infection
lalb05170  Human immunodeficiency virus 1 infection
lalb05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
lalb05417  Lipid and atherosclerosis
lalb05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lalb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    132511381 (MAP2K6)
   04015 Rap1 signaling pathway
    132511381 (MAP2K6)
   04668 TNF signaling pathway
    132511381 (MAP2K6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    132511381 (MAP2K6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    132511381 (MAP2K6)
   04664 Fc epsilon RI signaling pathway
    132511381 (MAP2K6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    132511381 (MAP2K6)
   04935 Growth hormone synthesis, secretion and action
    132511381 (MAP2K6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    132511381 (MAP2K6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    132511381 (MAP2K6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    132511381 (MAP2K6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    132511381 (MAP2K6)
   05161 Hepatitis B
    132511381 (MAP2K6)
   05163 Human cytomegalovirus infection
    132511381 (MAP2K6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    132511381 (MAP2K6)
   05169 Epstein-Barr virus infection
    132511381 (MAP2K6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    132511381 (MAP2K6)
   05135 Yersinia infection
    132511381 (MAP2K6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    132511381 (MAP2K6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    132511381 (MAP2K6)
   05022 Pathways of neurodegeneration - multiple diseases
    132511381 (MAP2K6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    132511381 (MAP2K6)
   05418 Fluid shear stress and atherosclerosis
    132511381 (MAP2K6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    132511381 (MAP2K6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:lalb01001]
    132511381 (MAP2K6)
Enzymes [BR:lalb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     132511381 (MAP2K6)
Protein kinases [BR:lalb01001]
 Serine/threonine kinases: STE group
  STE7 family
   132511381 (MAP2K6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Seadorna_VP7 Pkinase_fungal Choline_kinase Haspin_kinase CLP1_P DUF4344 APH
Other DBs
NCBI-GeneID: 132511381
NCBI-ProteinID: XP_059990528
LinkDB
Position
20:complement(57728989..57861273)
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDISMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKITVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSEEFADFTSQCLKKNSK
ERPTYPELMQHPFFTLHESKATDVASFVKSILGD
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagagaaaccctggccttaaaatcccaaaagaagcattt
gaacaacctcagaccagttccacgccacctcgagatttagactccaaagcttgcatttct
attggaaatcagaactttgaggtgaaggcggatgacctggagcctatagtggagctgggc
cggggggcgtacggggtggtggagaagatgcggcatgtgcccagcgggcagatcatggcg
gtgaagcggatccgggccacggtaaatagccaggagcagaaaaggttactgatggatctg
gatatttccatgaggaccgtggactgtccttttacggtcaccttttatggcgcactcttc
cgtgagggggatgtctggatctgcatggagctcatggacacgtccctagataaattctac
aaacaagtgatcgataaaggccaaacaattccagaggacatcttagggaaaataacagtt
tctattgtaaaagcattagaacatttgcacagtaagctctctgtgattcatcgagatgtc
aagccttccaatgtgctcatcaacaccctgggccaggtgaagatgtgcgattttggaatc
agtggctaccttgttgactccgtcgctaaaactatcgatgcaggatgcaaaccgtacatg
gcccccgagagaataaacccagagctcaaccagaagggatacagcgtgaagtccgacatt
tggagtctgggcatcaccatgatcgagctggccatccttcggtttccctatgattcgtgg
ggaactccttttcagcagctcaaacaggtggtggaggagccgtcgccacaactccccgca
gacaagttctccgaagagtttgctgactttacctcacagtgcttgaagaagaattccaaa
gagaggccaacatatccagagcttatgcaacatccatttttcaccctacacgaatccaaa
gcgacagatgtggcatcttttgtaaaatcgattcttggagactaa

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