Lagenorhynchus albirostris (white-beaked dolphin): 132511392
Help
Entry
132511392 CDS
T10760
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
132511392 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lalb03032
]
132511392 (TOP2A)
03036 Chromosome and associated proteins [BR:
lalb03036
]
132511392 (TOP2A)
Enzymes [BR:
lalb01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
132511392 (TOP2A)
DNA replication proteins [BR:
lalb03032
]
Eukaryotic type
DNA Topoisomerases
132511392 (TOP2A)
Chromosome and associated proteins [BR:
lalb03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
132511392 (TOP2A)
Centrosome formation proteins
Centriole proteins
132511392 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
132511392
NCBI-ProteinID:
XP_059990551
LinkDB
All DBs
Position
20:complement(39773228..39798690)
Genome browser
AA seq
1533 aa
AA seq
DB search
MEMSPLQPVDDNMQVNKTKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVESVTQQ
MWVYDEDIGINCREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWRDNMGRAGEMELKPFSGEDYTCITFHPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPIKGFRSYVDMYLKDKVDETGNALKIIHEQVNPRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVTKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQVKSFGSTCPLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLHHRFLEEFITPIVKVSKNKQEVAFYSLPEFEEWKN
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEMSILNSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLITDYREY
HTDTTVKFVVKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIDGKIIIENKPKKELIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCRLRNEKEQELETLKRKSPSDLWKEDLAAFVEELEAVEAKEKQDEQIGLPGKGGKA
KGKKTQRAEVLPSPCGKRVIPQVTIEMKAEAEKKIKKKIKNENTEGSSREDGMEIEGLKQ
RLEKKQKIEPGTKTKKQTTLPFKPVKKAKKRNPWSDSESDIDSNESNFDVPPREKEPRRA
ATKTKFTMDLDSDEDFSDFDENTQDEDRVPSDASPPRTTTSPKHTNKELKPQKSATSVTD
LNADDAKDNVPPPPSSPAADFPAVTKTTNPVPKKNVTVKKTAAKSQSSTSTTGAKKRAAP
KGTKKDPDLDSDVSKKPNPPKTKSHRKRKPSTSDDSDSNFEKMISKAVTSKKPKEDSDDF
HLDLDSAVASRAKSGRTKKPIKYLEESDEDDLF
NT seq
4602 nt
NT seq
+upstream
nt +downstream
nt
atggagatgtcaccactgcagcctgtagatgacaatatgcaagtcaacaaaacaaagaaa
aatgaagatgctaagaaaagactgtctattgaaagaatctatcagaagaaaacacaactg
gaacatattctgctccgcccagacacctacattggctctgtggaatcagtgacccagcaa
atgtgggtttacgatgaagatattggcattaactgtagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagtcaatgctgcagacaacaaacaaagggacccc
aaaatgtcttgtattagagtcacaattgacccggagaataatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atctttggacagctcctaacttctagtaactatgatgatgaagaaaagaaagtaacgggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggaa
acagccagtagagaatacaagaaaatgttcaaacagacatggagggataacatggggaga
gctggtgagatggaactcaagccctttagtggagaagattatacatgtattaccttccac
cctgatttgtctaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtt
agaagagcatatgatattgctggatccactaaagatgtcaaggtctttctcaatggaaat
aagcttccaataaaaggattccgtagctatgtagatatgtatctgaaggataaggtagat
gaaactggcaatgcactgaaaattatccatgaacaagtaaaccccaggtgggaagtgtgt
ttaacaatgagtgaaaaaggctttcagcaaatcagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtgactaaacttgttgatgtt
gtgaagaaaaagaacaagggtggtgttgcagtaaaagcacatcaggtaaaaaatcacatg
tggatttttgtgaacgccttaattgaaaacccaaccttcgactcccagacaaaagagaac
atgactttacaagtcaagagctttggatcaacgtgcccgttgagtgaaaaattcatcaaa
gctgcaattggctgtggtattgtagaaagcatactaaactgggtgaaatttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaaaggaattcccaaa
cttgatgatgccaatgatgcaggaggccgaaactccactgagtgtacacttatcctgaca
gagggagactcagctaaaactttggctgtttcaggccttggtgtggttgggagagacaag
tacggggttttccctcttagaggaaaaatgcttaatgttcgagaagcttctcataaacag
ataatggaaaatgctgaaattaacaatataatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactctgcgttatgggaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcataac
tggccctctcttctgcaccatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaagtggcattctatagccttcctgagtttgaagaatggaagaat
tctacgccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaagaagctaaagagtactttgcagatatgaaaagacatcgtatccaattcaaatat
tcaggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagatgat
cgaaaggaatggttaactcatttcatggaagatagaaggcaacgaaagttacttggcctt
cctgaggattacttatatgggcaaactaccacatatctgacatataatgacttcataaat
aaggaacttatcctgttctcaaattctgataatgagaggtctatcccatctatggtggat
ggtttgaagccaggtcagagaaaggttttgtttacatgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtagctgagatgtcctcttatcatcatggt
gagatgtcactaatgatgaccattatcaatttggctcagaactttgtgggtagcaataat
ctgaacctcttgcagcccattggtcagtttggtaccaggctgcatggtggcaaggattct
gctagtccccgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcacacgttaaggtttttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtgctgataaatggcgctgaaggaattggtactgggtgg
tcctgcaaaatccccaacttcgatgttcgtgaagttgtgaataacatcagacgtttgatg
gatggagaagaacctttgccaatgcttccaagttacaagaacttcaagggtactattgaa
gagctggctccaaatcaatatgtgattagtggtgaaatgtctattcttaattctacaacc
attgaaatctcagagcttcccatcagaacatggacccagacatataaagaacaggttcta
gaacccatgttgaatggcactgagaagacaccccctctgataacagattatagggaatac
cacacagacaccactgtgaagtttgttgtgaagatgactgaagaaaaactggcagaggca
gagagagttggactacacaaagtcttcaaactccaaactagtctcacatgcaactctatg
gtgctttttgaccacgtaggctgtttaaagaaatacgacacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttctaggaatg
cttggcgctgaatctgctaaactgaataatcaggctcgctttatcttagagaaaatagat
ggcaaaataatcattgaaaacaagcctaagaaagaattaattaaagttctgattcaaaga
ggttatgattcggatcctgtgaaggcttggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgactctgtaacagat
tctggaccaaccttcaactaccttcttgatatgcctctttggtatctaaccaaggaaaag
aaagatgaactgtgcagactaagaaatgaaaaagagcaagagctagaaacattaaagaga
aagagtccatcagatttgtggaaagaagacttggctgcttttgttgaagagctggaggct
gttgaagcaaaggagaaacaagatgaacaaataggacttcctgggaaaggtgggaaagca
aaggggaaaaaaacacaaagggcagaagttttgccttctccatgtggaaaaagagtcatc
ccccaagtgaccatagagatgaaagcagaggcagaaaagaaaattaaaaaaaaaattaag
aatgaaaatactgaaggaagctctcgagaggatgggatggaaatagaaggcctaaaacag
agattagaaaagaaacagaaaatagaaccaggtaccaagacaaagaaacaaactacattg
ccatttaaaccagtcaagaaagccaaaaagagaaacccctggtctgattcggaatcagat
atagacagtaacgaaagtaattttgatgtccctccccgagaaaaagagccacggagagca
gcaacaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgat
gaaaacactcaagatgaagatcgtgtcccatcagatgctagtccacctaggaccacaact
tccccaaaacatactaacaaagaactgaagccacagaaaagtgccacatcagtaacggac
cttaacgctgatgatgccaaggataatgtaccacctcctccaagctctcctgctgctgat
ttcccagctgtaactaaaaccacaaaccctgttcctaaaaagaacgtgacagtgaagaag
acggcagcaaaaagtcagtcttccacctctactacaggggccaaaaaaagggctgcacca
aaaggaaccaaaaaggatccagacttggattctgatgtctctaaaaagcctaatcccccc
aaaaccaagagtcaccgcaaaaggaagccgtccacttctgatgattccgactctaatttt
gagaaaatgatttctaaagcagtcacaagcaagaaacccaaggaggacagtgatgacttc
cacctggacttagactcagctgtggcttctcgggcaaaatcgggacggacaaagaaacct
ataaagtacctcgaagaatcagatgaagatgatctgttttaa
DBGET
integrated database retrieval system
